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树脂填充聚醚砜纤维吸附剂对牛血清蛋白吸附性能的研究 被引量:1
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作者 张玉忠 Borneman Z +1 位作者 Koops G-H Wessling M 《高分子学报》 SCIE CAS CSCD 北大核心 2006年第2期350-355,共6页
重点研究树脂填充聚醚砜(PES)纤维吸附剂与模型蛋白质牛血清蛋白(BSA)之间的吸附与脱附行为.结果表明,蛋白质BSA在树脂填充PES纤维吸附剂中的平衡吸附过程较好地符合朗格缪尔吸附模型,树脂Lewatit CNP80ws填充PES吸附剂的最大吸... 重点研究树脂填充聚醚砜(PES)纤维吸附剂与模型蛋白质牛血清蛋白(BSA)之间的吸附与脱附行为.结果表明,蛋白质BSA在树脂填充PES纤维吸附剂中的平衡吸附过程较好地符合朗格缪尔吸附模型,树脂Lewatit CNP80ws填充PES吸附剂的最大吸附容量约为139mg BSA/g吸附剂.表面具有开孔结构的树脂填充PES纤维吸附剂的吸附速率较快,在不同结构纤维吸附剂中BSA的扩散系数在1.82×10^-14~8.7×10^-14m^2/s范围内变化.另外,考察了BSA溶液的pH与洗脱剂等因素对吸附剂吸附与脱附性能的影响,研究结果对蛋白质的实际分离纯化具有重要的参考价值. 展开更多
关键词 纤维吸附剂 膜吸附剂 填充膜 聚醚砜 牛血清蛋白
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微结构芯片优化牙种植体穿龈部位形貌特征
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作者 包崇云 王买全 +4 位作者 R. Trukenmuller 张强 欧国敏 宫苹 C.A. van Blitterswijk 《中国口腔种植学杂志》 2009年第2期48-49,共2页
目的:通过制备精确控制微结构的材料样品,筛选影响C2C12细胞及S.a和P.g细菌粘附、增殖的关键微结构,探索优化实现软组织密封的经皮/穿龈部位材料形貌特征。方法:①微米结构芯片样品制备:采用纳米HA浆料,制备表面亚微米粗糙度HA片。用激... 目的:通过制备精确控制微结构的材料样品,筛选影响C2C12细胞及S.a和P.g细菌粘附、增殖的关键微结构,探索优化实现软组织密封的经皮/穿龈部位材料形貌特征。方法:①微米结构芯片样品制备:采用纳米HA浆料,制备表面亚微米粗糙度HA片。用激光消融法于HA片上23个大小为400μm×400μm区域(其中一个区域为对照),分别制作尺度为1μm,3μm,5μm,10μm;深度与制备尺度相当;间距10μm,20μm;形状为线条、交叉线条、圆孔和三角形的微结构,形成HA微结构芯片。再以HA微结构芯片为模版,翻制形成与HA微结构一致的PDMS微结构芯片样品。②光镜、激光共聚焦显微镜、扫描电镜研究C2C12细胞、S.a和P.g细菌在微米结构芯片粘附、增殖行为。结果:①SEM示在PDMS与HA制备成一样微结构模式的微结构芯片。②C2C12细胞在不同微米结构区域粘附、增殖数量不同,细胞更容易间距大,微结构尺度小的区域粘附与增殖,特别在亚微米凸凹晶粒及纳米界孔区域。两种细菌均主要粘附于微米结构区,沟裂越多,粘附细菌越多,沟裂宽度越大,粘附细菌越多,与微米结构的形状没有太大关系。而亚微米结构对照区域粘附较少。细胞、细菌在HA、PDMS相同的微结构区均表现出相似的粘附、增殖特性。讨论:生物材料的微结构和局部微环境的微形貌对细胞迁移、粘附、增殖、分化等行为均产生着影响,同时对微生物的粘附、增殖也产生影响。结论:①微米结构芯片可望为实现高通量筛选分析微结构对细胞及细菌行为的影响研究。2.细胞易于在亚微米结构粘附、增殖,细菌易于在微米结构而不易粘附于亚微米结构粘附、增殖,为进一步探索优化器件经皮/穿龈部位材料形貌制备提供初步理论依据。 展开更多
关键词 微结构 牙种植体 激光消融法 形貌特征 PDMS 生物材料 增殖特性 结构区 高通量筛选 局部微环境
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Current status of laparoscopic and robotic ventral mesh rectopexy for external and internal rectal prolapse 被引量:20
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作者 Jan J van Iersel Tim JC Paulides +3 位作者 Paul M Verheijen John W Lumley Ivo AMJ Broeders Esther CJ Consten 《World Journal of Gastroenterology》 SCIE CAS 2016年第21期4977-4987,共11页
External and internal rectal prolapse with their affiliated rectocele and enterocele, are associated with debilitating symptoms such as obstructed defecation, pelvic pain and faecal incontinence. Since perineal proced... External and internal rectal prolapse with their affiliated rectocele and enterocele, are associated with debilitating symptoms such as obstructed defecation, pelvic pain and faecal incontinence. Since perineal procedures are associated with a higher recurrence rate, an abdominal approach is commonly preferred. Despite the description of greater than three hundred different procedures, thus far no clear superiority of one surgical technique has been demonstrated. Ventral mesh rectopexy(VMR) is a relatively new and promising technique to correct rectal prolapse. In contrast to the abdominal procedures of past decades, VMR avoids posterolateral rectal mobilisation and thereby minimizes the risk of postoperative constipation. Because of a perceived acceptable recurrence rate, good functional results and low mesh-related morbidity in the short to medium term, VMR has been popularized in the past decade. Laparoscopic or robotic-assisted VMR is now being progressively performed internationally and several articles and guidelines propose the procedure as the treatment of choice for rectal prolapse. In this article, an outline of the current status of laparoscopic and robotic ventral mesh rectopexy for the treatment of internal and external rectal prolapse is presented. 展开更多
关键词 Laparoscopic ventral mesh rectopexy Robot Rectal prolapse External rectal prolapse Internal rectal prolapse RECTOCELE Mesh erosion Obstructed defecation Faecal incontinence Biological mesh
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Connect & Drive:design and evaluation of cooperative adaptive cruise control for congestion reduction 被引量:10
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作者 Jeroen PLOEG Alex F.A.SERRARENS Geert J.HEIJENK 《Journal of Modern Transportation》 2011年第3期207-213,共7页
Road throughput can be increased by driving at small inter-vehicle time gaps. The amplification of velocity disturbances in upstream direction, however, poses limitations to the minimum feasible time gap. This effect ... Road throughput can be increased by driving at small inter-vehicle time gaps. The amplification of velocity disturbances in upstream direction, however, poses limitations to the minimum feasible time gap. This effect is covered by the notion of string stability. String-stable behavior is thus considered an essential requirement for the design of automatic distance control systems, which are needed to allow for safe driving at time gaps well below 1 s. Using wireless inter-vehicle communications to provide real-time information of the preceding vehicle, in addition to the information obtained by common Adaptive Cruise Control (ACC) sensors, appears to significantly decrease the feasible time gap, which is shown by practical experiments with a test fleet consisting of six passenger vehicles. The large-scale deployment of this system, known as Cooperative ACC (CACC), however, poses challenges with respect to the reliability of the wireless communication system. A solution for this scalability problem can be found in decreasing the transmission power and/or beaconing rate, or adapting the communications protocol. Although the main CACC objective is to increase road throughput, the first commercial application of CACC is foreseen to be in truck platooning, since short distance following is expected to yield significant fuel savings in this case. 展开更多
关键词 cooperative adaptive cruise control (CACC) string stability cooperative driving traffic congestion fuel efficiency
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INVESTIGATIONS ON VINYLENE CARBONATE Ⅰ. PREPARATION AND PROPERTIES OF POLY-(VINYLENEC ARBONATE)
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作者 黄家贤 陈国华 +2 位作者 EDDY TIJSMA LEEN VAN DER DOES ADRIAAN BANTJES 《Chinese Journal of Polymer Science》 SCIE CAS CSCD 1990年第3期197-203,共7页
Bulk polymerization of vinylene carbonate using t-butylperoxypivalate at 40℃gave colourless, high molecular weight poly(vinylene carbonate) (PVCA). Solutions of PVCA in acetone and DMF are not stable at 25℃and this ... Bulk polymerization of vinylene carbonate using t-butylperoxypivalate at 40℃gave colourless, high molecular weight poly(vinylene carbonate) (PVCA). Solutions of PVCA in acetone and DMF are not stable at 25℃and this degradation was studied. From measurements in DMF with unfractionated PVCA a Mark-Houwink equation was obtained: 展开更多
关键词 Vinylene carbonate POLYMERIZATION High Molecular Weight DEGRADATION Mark-Houwink Equation.
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Precision in harsh environments 被引量:3
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作者 Paddy French Gijs Krijnen Fred Roozeboom 《Microsystems & Nanoengineering》 EI 2016年第1期61-72,共12页
Microsystems are increasingly being applied in harsh and/or inaccessible environments,but many markets expect the same level of functionality for long periods of time.Harsh environments cover areas that can be subject... Microsystems are increasingly being applied in harsh and/or inaccessible environments,but many markets expect the same level of functionality for long periods of time.Harsh environments cover areas that can be subjected to high temperature,(bio)-chemical and mechanical disturbances,electromagnetic noise,radiation,or high vacuum.In the field of actuators,the devices must maintain stringent accuracy specifications for displacement,force,and response times,among others.These new requirements present additional challenges in the compensation for or elimination of cross-sensitivities.Many state-of-the-art precision devices lose their precision and reliability when exposed to harsh environments.It is also important that advanced sensor and actuator systems maintain maximum autonomy such that the devices can operate independently with low maintenance.The next-generation microsystems will be deployed in remote and/or inaccessible and harsh environments that present many challenges to sensor design,materials,device functionality,and packaging.All of these aspects of integrated sensors and actuator microsystems require a multidisciplinary approach to overcome these challenges.The main areas of importance are in the fields of materials science,micro/nano-fabrication technology,device design,circuitry and systems,(first-level)packaging,and measurement strategy.This study examines the challenges presented by harsh environments and investigates the required approaches.Examples of successful devices are also given. 展开更多
关键词 atomic layer deposition harsh environments micro/nano-fabrication technology PACKAGING SENSORS
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