The Bikou volcanic terrane is predominated by subalkaline tholeiitic lavas. Rock samples display lower initial ratios of Sr and Nd, 0.701248-0.704413 and 0.511080-0.512341 respectively. 207Pb and 208Pb are significant...The Bikou volcanic terrane is predominated by subalkaline tholeiitic lavas. Rock samples display lower initial ratios of Sr and Nd, 0.701248-0.704413 and 0.511080-0.512341 respectively. 207Pb and 208Pb are significantly enriched in the lavas. Most samples have positive εNd, which indicates that the magma was derived from EM-type mantle source, while a few samples with negative εNd indicate that there was contamination in the magma evolution. Magma differentiation is demonstrated by variations of LREE and LILE from depletion to enrichment. Additionally, normalized REE patterns and trace elements showed that lavas from the Bikou volcanic terrane have similar characteristics to those of basalts in arc settings caused by subduction and collision. Analyses showed that the Bikou volcanic terrane is a volcanic arc. New evidence proved that the Hengdan Group, north of the Bikou arc, is a turbidite terrane filling a forearc basin. Consequently, the Bikou volcanic terrane and the Hengdan turbidite terrane construct an arc-basin system. New SHRIMP ages showed that this arc-basin system developed on the northern margin of the Yangtze craton in the Neoproterozoic (846-776 Ma), and this arc-basin system is in agreement with the tectonic processes of Rodinia in the Neoproterzoic.展开更多
AIM: To assess whether the molecular markers of malignant tumors could improve the understanding of tumor characteristics, and to observe the characteristics of expression of cell cycle markers Ki-67 and cyclin A in e...AIM: To assess whether the molecular markers of malignant tumors could improve the understanding of tumor characteristics, and to observe the characteristics of expression of cell cycle markers Ki-67 and cyclin A in esophageal carcinoma and to analyze the relationship between proliferative activity of cancer cells and clinicopathological factors. METHODS: Seventy of surgically resected esophageal squamous cell carcinoma (SCC) were examined by immun-ohistochemistry utilizing commercially available antibodies. Nuclear staining was regarded as a positive result. At least 50 fields in each tumor and non-tumor section were evaluated at a medium power (×200) to determine the proportion of tumor cells and the staining intensity of nuclei in the entire sections. RESULTS: Ki-67 and cyclin A were only expressed in base cells of normal esophageal mucosa. The positive immuno-staining of nuclei of SCC was significantly higher than that in normal esophageal mucosa (t = 13.32 and t = 7.52, respectively, P<0.01). The distribution of positively stained was more diffuse and stronger in poorly differentiated SCC. Both Ki-67 and cyclin A expressions were related to histological grades of tumors (t = 3.5675 and t = 3.916; t = 2.13, respectively, P<0.05) but not to the sex and age of the patients, tumor size, lymphatic invasion, location, or stage grouping. CONCLUSION: The proliferative activity of cancer cells may be understood by immunohistochemistry of Ki-67 and cyclin A in Chinese patients with esophageal SCC. These cell cycle markers may serve as an indicator of cancer cell proliferation rate. The overexpression of cell cycle markers Ki-67 and cyclin A suggests the poor SCC differentiation in patients with esophageal carcinoma.展开更多
The dissolved ionic constituents of groundwaters are, in part, a record of the minerals and rocks in aquifers through which the water has flowed. The chemical composition and association of these major ions in groundw...The dissolved ionic constituents of groundwaters are, in part, a record of the minerals and rocks in aquifers through which the water has flowed. The chemical composition and association of these major ions in groundwaters have been used to trace groundwater flow paths and sources. In general, the chemical composition of water in carbonate\|rock aquifers is dominated by calcium, magnesium, and bicarbonate, whereas sodium, chloride, and sulfate can be dominant ions in the water that comes from volcanic aquifers or clay minerals. Since the \{1990’s\}, we have dealt with the geochemistry of groundwaters from more than 100 springs and wells in southern Nevada and eastern California, USA for major solutes and trace elements. This paper compiles the hydrochemical data of major ions of these groundwaters. Based on major ion geochemistry, groundwaters from southern Nevada and eastern California can be classified as carbonate aquifer water, volcanic aquifer water, and mixing water (either mixing of carbonate and volcanic aquifer waters or mixing with local recharges). Piper and Stiff diagrams of major ions have graphically shown the general chemical characteristics, classifications, and mixing relationships of groundwaters from southern Nevada and eastern California.展开更多
Objective: To describe the profiles and changing tendency of infant mortality born to teenage mother in the state of Nevada, 1980-2000, and explore the risk factors of infant mortality. Methods: The Nevada Linked Birt...Objective: To describe the profiles and changing tendency of infant mortality born to teenage mother in the state of Nevada, 1980-2000, and explore the risk factors of infant mortality. Methods: The Nevada Linked Birth/Infant Death data sets in 1980-2000 was analyzed. Total of 421964 live births were registered, which included 55419 live births born to teenage mother aged 10-20 years old. Multivariate binary logistic regression model was used to explore the risk factors of infant mortality and estimate the strength of association. Results: Infant mortality rate (IMR) born to teenage mother varied from 5.69 to 14.72 per 1000 live births in 1980-2000, mean IMR was 9.51 per 1000 live births during these 21 years, which were higher than IMRs born to 20 years or older mothers every year. IMRs in two groups seem to have an overall decline by year during this period. The infant mortality rate born to black teenage mother reached to 16.07 per 1000 live births, which was the highest one and significantly higher than those born to white, native American, Asian and other race mothers. Infant mortality rate generally appeared to decline by the increase of mothers age and 16 years old should be an important cut point. This study showed that Congenital anomalies: Club foot, Abnormal conditions of newborn: Meconium aspiration syndrome, Congenital anomaly: Heart malformation, Method of delivery: Repeat Csection, Abnormal conditions of newborn: Assisted ventilation <30min, Birth weight group, Tobacco use, The time mother prenatal care began were significantly positively associated with infant mortality born to teenage mothers, their odds ratios were 24.25, 10.68, 10.23, 4.73, 2.49, 2.00, 1.99 and 1.19 respectively. The clinical gestation estimates was significantly negatively associated with infant mortality as odds ratio of 0.79. Conclusion: Infant mortality born to teenage mother is one of important public problem in Nevada, there are different risk factors related to infant death born to teenage and adult mother. Teenage pregnancy and its outcome should be paid more attention to study.展开更多
Caffeoyl-Coenzyme A 3-O-Methyltransferase (CCoAOMT) is a key enzyme in lignin biosynthesis pathway. Three rice CCoAOMT genes were identified and designated as OsCOA1, OsCOA20 and OsCOA26. OsCOA1 contains four exons an...Caffeoyl-Coenzyme A 3-O-Methyltransferase (CCoAOMT) is a key enzyme in lignin biosynthesis pathway. Three rice CCoAOMT genes were identified and designated as OsCOA1, OsCOA20 and OsCOA26. OsCOA1 contains four exons and three introns, while the other two have three exons and two introns. The deduced amino acid sequences of these rice genes share a high identity (75.43%) with other plant CCoAOMT proteins and contain the CCoAOMT specific motifs. Phylogenetic analysis indicates that OsCOA1 has the closest evolutionary relationship to maize CCoAOMT. In contrast, OsCOA20 and OsCOA26 belong to another clade. Northern blot analyses and in situ hybridization studies in- dicate that the three rice CCoAOMT genes are highly ex- pressed in developing sclerenchyma cells and vessel bundles of young leaves, suggesting that they are probably involved in constitutive lignification.展开更多
基金supports from the National Natural Science Foundation of China(grants 40172071 and 40211120151 to Yan Quanren)the Ministry of Science and Technology of the People’s Republic of China(grant 2202CB412608 to Wang Zongqi)+2 种基金the China Geological Survey(grant DKD2001002 to Wang Zongqi)the University of Nevada Las Vegas(to Hanson)and the Geological Society of America(to Druschke)are gratefully appreciated.
文摘The Bikou volcanic terrane is predominated by subalkaline tholeiitic lavas. Rock samples display lower initial ratios of Sr and Nd, 0.701248-0.704413 and 0.511080-0.512341 respectively. 207Pb and 208Pb are significantly enriched in the lavas. Most samples have positive εNd, which indicates that the magma was derived from EM-type mantle source, while a few samples with negative εNd indicate that there was contamination in the magma evolution. Magma differentiation is demonstrated by variations of LREE and LILE from depletion to enrichment. Additionally, normalized REE patterns and trace elements showed that lavas from the Bikou volcanic terrane have similar characteristics to those of basalts in arc settings caused by subduction and collision. Analyses showed that the Bikou volcanic terrane is a volcanic arc. New evidence proved that the Hengdan Group, north of the Bikou arc, is a turbidite terrane filling a forearc basin. Consequently, the Bikou volcanic terrane and the Hengdan turbidite terrane construct an arc-basin system. New SHRIMP ages showed that this arc-basin system developed on the northern margin of the Yangtze craton in the Neoproterozoic (846-776 Ma), and this arc-basin system is in agreement with the tectonic processes of Rodinia in the Neoproterzoic.
基金Supported by the Key Medical Talent Foundation of Jiangsu Province, China, No. 2001-34 and 2002-15
文摘AIM: To assess whether the molecular markers of malignant tumors could improve the understanding of tumor characteristics, and to observe the characteristics of expression of cell cycle markers Ki-67 and cyclin A in esophageal carcinoma and to analyze the relationship between proliferative activity of cancer cells and clinicopathological factors. METHODS: Seventy of surgically resected esophageal squamous cell carcinoma (SCC) were examined by immun-ohistochemistry utilizing commercially available antibodies. Nuclear staining was regarded as a positive result. At least 50 fields in each tumor and non-tumor section were evaluated at a medium power (×200) to determine the proportion of tumor cells and the staining intensity of nuclei in the entire sections. RESULTS: Ki-67 and cyclin A were only expressed in base cells of normal esophageal mucosa. The positive immuno-staining of nuclei of SCC was significantly higher than that in normal esophageal mucosa (t = 13.32 and t = 7.52, respectively, P<0.01). The distribution of positively stained was more diffuse and stronger in poorly differentiated SCC. Both Ki-67 and cyclin A expressions were related to histological grades of tumors (t = 3.5675 and t = 3.916; t = 2.13, respectively, P<0.05) but not to the sex and age of the patients, tumor size, lymphatic invasion, location, or stage grouping. CONCLUSION: The proliferative activity of cancer cells may be understood by immunohistochemistry of Ki-67 and cyclin A in Chinese patients with esophageal SCC. These cell cycle markers may serve as an indicator of cancer cell proliferation rate. The overexpression of cell cycle markers Ki-67 and cyclin A suggests the poor SCC differentiation in patients with esophageal carcinoma.
文摘The dissolved ionic constituents of groundwaters are, in part, a record of the minerals and rocks in aquifers through which the water has flowed. The chemical composition and association of these major ions in groundwaters have been used to trace groundwater flow paths and sources. In general, the chemical composition of water in carbonate\|rock aquifers is dominated by calcium, magnesium, and bicarbonate, whereas sodium, chloride, and sulfate can be dominant ions in the water that comes from volcanic aquifers or clay minerals. Since the \{1990’s\}, we have dealt with the geochemistry of groundwaters from more than 100 springs and wells in southern Nevada and eastern California, USA for major solutes and trace elements. This paper compiles the hydrochemical data of major ions of these groundwaters. Based on major ion geochemistry, groundwaters from southern Nevada and eastern California can be classified as carbonate aquifer water, volcanic aquifer water, and mixing water (either mixing of carbonate and volcanic aquifer waters or mixing with local recharges). Piper and Stiff diagrams of major ions have graphically shown the general chemical characteristics, classifications, and mixing relationships of groundwaters from southern Nevada and eastern California.
文摘Objective: To describe the profiles and changing tendency of infant mortality born to teenage mother in the state of Nevada, 1980-2000, and explore the risk factors of infant mortality. Methods: The Nevada Linked Birth/Infant Death data sets in 1980-2000 was analyzed. Total of 421964 live births were registered, which included 55419 live births born to teenage mother aged 10-20 years old. Multivariate binary logistic regression model was used to explore the risk factors of infant mortality and estimate the strength of association. Results: Infant mortality rate (IMR) born to teenage mother varied from 5.69 to 14.72 per 1000 live births in 1980-2000, mean IMR was 9.51 per 1000 live births during these 21 years, which were higher than IMRs born to 20 years or older mothers every year. IMRs in two groups seem to have an overall decline by year during this period. The infant mortality rate born to black teenage mother reached to 16.07 per 1000 live births, which was the highest one and significantly higher than those born to white, native American, Asian and other race mothers. Infant mortality rate generally appeared to decline by the increase of mothers age and 16 years old should be an important cut point. This study showed that Congenital anomalies: Club foot, Abnormal conditions of newborn: Meconium aspiration syndrome, Congenital anomaly: Heart malformation, Method of delivery: Repeat Csection, Abnormal conditions of newborn: Assisted ventilation <30min, Birth weight group, Tobacco use, The time mother prenatal care began were significantly positively associated with infant mortality born to teenage mothers, their odds ratios were 24.25, 10.68, 10.23, 4.73, 2.49, 2.00, 1.99 and 1.19 respectively. The clinical gestation estimates was significantly negatively associated with infant mortality as odds ratio of 0.79. Conclusion: Infant mortality born to teenage mother is one of important public problem in Nevada, there are different risk factors related to infant death born to teenage and adult mother. Teenage pregnancy and its outcome should be paid more attention to study.
文摘Caffeoyl-Coenzyme A 3-O-Methyltransferase (CCoAOMT) is a key enzyme in lignin biosynthesis pathway. Three rice CCoAOMT genes were identified and designated as OsCOA1, OsCOA20 and OsCOA26. OsCOA1 contains four exons and three introns, while the other two have three exons and two introns. The deduced amino acid sequences of these rice genes share a high identity (75.43%) with other plant CCoAOMT proteins and contain the CCoAOMT specific motifs. Phylogenetic analysis indicates that OsCOA1 has the closest evolutionary relationship to maize CCoAOMT. In contrast, OsCOA20 and OsCOA26 belong to another clade. Northern blot analyses and in situ hybridization studies in- dicate that the three rice CCoAOMT genes are highly ex- pressed in developing sclerenchyma cells and vessel bundles of young leaves, suggesting that they are probably involved in constitutive lignification.