Different leaf(evergreen vs.deciduous habit)and xylem(diffuse-vs.ring-porous wood)traits represent contrasting strategies to face seasonal changes in water availability and temperature.However,how contrasting leaf and...Different leaf(evergreen vs.deciduous habit)and xylem(diffuse-vs.ring-porous wood)traits represent contrasting strategies to face seasonal changes in water availability and temperature.However,how contrasting leaf and xylem habits of coexisting tree species affect stem wood formation and tree-ring development remains poorly understood.Here,we investigated the spatio-temporal patterns of wood formation in two deciduous oaks(Quercus faginea and Quercus petraea)and two evergreen oaks(Quercus ilex and Quercus suber)coexisting in seasonally dry Mediterranean forests along an aridity gradient in Spain.We hypothesized that growth responses to drought and intra-and inter-annual growth patterns would differ between functional groups.We simulated intra-and interannual growth using a modified version of the Vaganov-Shashkin(VS)process-based,growth model.The VS model simulations were used to estimate growth changes under a high emission scenario(RCP 8.5)for the current distribution of the study oak species and to forecast their future performance under warm(4.8℃)conditions in the Iberian Peninsula.Our simulations indicate that climate warming would induce a shortening of the ringgrowth season and a reduction of radial growth in evergreen and deciduous Mediterranean oaks,particularly in dry sites from southern and eastern Iberia currently occupied by Q.ilex and Q.faginea.Evergreen oaks may better recover after dry periods than deciduous oaks by resuming growth after the summer drought.Low soil water availability in spring would be more detrimental to growth of deciduous oaks.Process-based growth models should be refined and validated to better forecast changes in tree growth as a function of climate.展开更多
There is an increasing interest in restoring degraded forests,which occupy half of the forest areas.Among the forms of restoration,passive restoration,which involves the elimination of degrading factors and the free e...There is an increasing interest in restoring degraded forests,which occupy half of the forest areas.Among the forms of restoration,passive restoration,which involves the elimination of degrading factors and the free evolution of natural dynamics by applying minimal or no management,is gaining attention.Natural dynamics is difficult to predict due to the influence of multiple interacting factors such as climatic and edaphic conditions,composition and abundance of species,and the successional character of these species.Here,we study the natural dynamics of a mixed forest located in central Spain,which maintained an open forest structure,due to intensive use,until grazing and cutting were banned in the 1960s.The most frequent woody species in this forest are Fagus sylvatica,Quercus petraea,Quercus pyrenaica,Ilex aquifolium,Sorbus aucuparia,Sorbus aria and Prunus avium,with contrasting shade and drought tolerance.These species are common in temperate European deciduous forest and are found here near their southern distribution limit,except for Q.pyrenaica.In order to analyze forest dynamics and composition,three inventories were carried out in 1994,2005 and 2015.Our results show that,despite the Mediterranean influence,the natural dynamics of this forest has been mainly determined by different levels of shade tolerance.After the abandonment of grazing and cutting,Q.pyrenaica expanded rapidly due to its lower shade tolerance,whereas after canopy closure and forest densification,shade-tolerant species gained ground,particularly F.sylvatica,despite its lower drought and late-frost tolerance.If the current dynamics continue,F.sylvatica will overtake the rest of the species,which will be relegated to sites with shallow soils and steep slopes.Simultaneously,all the multi-centennial beech trees,which are undergoing a rapid mortality and decline process,will disappear.展开更多
This paper proposes a methodology for the quantitative robustness evaluation of PID controllers employed in a DC motor. The robustness analysis is performed employing a 2~3 factorial experimental design for a fraction...This paper proposes a methodology for the quantitative robustness evaluation of PID controllers employed in a DC motor. The robustness analysis is performed employing a 2~3 factorial experimental design for a fractional order proportional integral and derivative controller(FOPID), integer order proportional integral and derivative controller(IOPID)and the Skogestad internal model control controller(SIMC). The factors assumed in experiment are the presence of random noise,external disturbances in the system input and variable load. As output variables, the experimental design employs the system step response and the controller action. Practical implementation of FOPID and IOPID controllers uses the MATLAB stateflow toolbox and a NI data acquisition system. Results of the robustness analysis show that the FOPID controller has a better performance and robust stability against the experiment factors.展开更多
Communication based train control systems(CBTC) must work even in the worst situation—train crossing.This paper models the propagation characteristics in one of the most common and pivotal scenarios—train crossing i...Communication based train control systems(CBTC) must work even in the worst situation—train crossing.This paper models the propagation characteristics in one of the most common and pivotal scenarios—train crossing in subway tunnels which is rarely mentioned in previous publications.Firsdy,measurements for train crossing scenario at 2.4 GHz in a real subway line in Madrid have been made.The field measurement is the most reliable way to reveal the propagation characteristics involving shadowing effect and fast fading.Moreover,to precisely describe the fast fading distribution and eliminate the inevitable weak points of traditional fitting way,a best numerical approximation method using Legendre orthogonal polynomials has been proposed.Comparisons show that this method works better and is of greater physical significance.Finally,a complete statistical model is given and all the coefficients can be applied by system designers for the link and system level simulations.展开更多
Response to vernalization and photoperiod are the main determinants controlling the time to flowering in temperate cereals. While the individual genes that determine a plant's response to these environmental signa...Response to vernalization and photoperiod are the main determinants controlling the time to flowering in temperate cereals. While the individual genes that determine a plant's response to these environmental signals are well characterized, the combinatorial effect on flowering time of allelic variants for multiple genes remains unresolved. This study investigated the genetic control of flowering-time in a biparental population of spring barley, derived from a wide cross between a late-flowering European and an early-flowering North-American cultivar. While the major flowering time genes are not segregating in the Beka ×Logan cross, large variation in flowering was observed. We identified five QTL, with both parents found to contribute early alleles. The catalog of QTL discovered aligns with several candidate genes affecting flowering time in barley. The combination of particular alleles at HvCEN, HvELF3 and HvFT1 in Logan are responsible for the earliness of this cultivar. Interestingly, earliness for flowering could be further enhanced, with Beka found to contribute three early alleles, including a QTL colocating with a HvFD-like gene, suggesting that there are diverse aspects of the flowering-time pathway that have been manipulated in these two cultivars. Epistatic interactions between flowering-time QTL or candidate genes were observed in field data and confirmed under controlled conditions. The results of this study link photoperiod-dependent flowering-time genes with earliness per se genes into a single model, thus providing a unique framework that can be used by geneticists and breeders to optimize flowering time in barley.展开更多
Background Genotype-by-sequencing has been proposed as an alternative to SNP genotyping arrays in genomic selection to obtain a high density of markers along the genome.It requires a low sequencing depth to be cost ef...Background Genotype-by-sequencing has been proposed as an alternative to SNP genotyping arrays in genomic selection to obtain a high density of markers along the genome.It requires a low sequencing depth to be cost effective,which may increase the error at the genotype assigment.Third generation nanopore sequencing technology offers low cost sequencing and the possibility to detect genome methylation,which provides added value to genotype-by-sequencing.The aim of this study was to evaluate the performance of genotype-by-low pass nanopore sequencing for estimating the direct genomic value in dairy cattle,and the possibility to obtain methylation marks simultaneously.Results Latest nanopore chemistry(LSK14 and Q20)achieved a modal base calling accuracy of 99.55%,whereas previous kit(LSK109)achieved slightly lower accuracy(99.1%).The direct genomic value accuracy from genotype-by-low pass sequencing ranged between 0.79 and 0.99,depending on the trait(milk,fat or protein yield),with a sequencing depth as low as 2×and using the latest chemistry(LSK114).Lower sequencing depth led to biased estimates,yet with high rank correlations.The LSK109 and Q20 achieved lower accuracies(0.57-0.93).More than one million high reliable methylated sites were obtained,even at low sequencing depth,located mainly in distal intergenic(87%)and promoter(5%)regions.Conclusions This study showed that the latest nanopore technology in useful in a LowPass sequencing framework to estimate direct genomic values with high reliability.It may provide advantages in populations with no available SNP chip,or when a large density of markers with a wide range of allele frequencies is needed.In addition,low pass sequencing provided nucleotide methylation status of>1 million nucleotides at≥10×,which is an added value for epigenetic studies.展开更多
Future components to enhance the basic,native security of 5G networks are either complex mechanisms whose impact in the requiring 5G communications are not considered,or lightweight solutions adapted to ultrareliable ...Future components to enhance the basic,native security of 5G networks are either complex mechanisms whose impact in the requiring 5G communications are not considered,or lightweight solutions adapted to ultrareliable low-latency communications(URLLC)but whose security properties remain under discussion.Although different 5G network slices may have different requirements,in general,both visions seem to fall short at provisioning secure URLLC in the future.In this work we address this challenge,by introducing cost-security functions as a method to evaluate the performance and adequacy of most developed and employed non-native enhanced security mechanisms in 5G networks.We categorize those new security components into different groups according to their purpose and deployment scope.We propose to analyze them in the context of existing 5G architectures using two different approaches.First,using model checking techniques,we will evaluate the probability of an attacker to be successful against each security solution.Second,using analytical models,we will analyze the impact of these security mechanisms in terms of delay,throughput consumption,and reliability.Finally,we will combine both approaches using stochastic cost-security functions and the PRISM model checker to create a global picture.Our results are first evidence of how a 5G network that covers and strengthened all security areas through enhanced,dedicated non-native mechanisms could only guarantee secure URLLC with a probability of∼55%.展开更多
Since 2014,"Bring Your Own Data"workshops(BYODs)have been organised to inform people about the process and benefits of making resources Findable,Accessible,Interoperable,and Reusable(FAIR,and the FAIRificati...Since 2014,"Bring Your Own Data"workshops(BYODs)have been organised to inform people about the process and benefits of making resources Findable,Accessible,Interoperable,and Reusable(FAIR,and the FAIRification process).The BYOD workshops'content and format differ depending on their goal,context,and the background and needs of participants.Data-focused BYODs educate domain experts on how to make their data FAIR to find new answers to research questions.Management-focused BYODs promote the benefits of making data FAIR and instruct project managers and policy-makers on the characteristics of FAIRification projects.Software-focused BYODs gather software developers and experts on FAIR to implement or improve software resources that are used to support FAIRification.Overall,these BYODs intend to foster collaboration between different types of stakeholders involved in data management,curation,and reuse(e.g.domain experts,trainers,developers,data owners,data analysts,FAIR experts).The BYODs also serve as an opportunity to learn what kind of support for FAIRification is needed from different communities and to develop teaching materials based on practical examples and experience.In this paper,we detail the three different structures of the BYODs and describe examples of early BYODs related to plant breeding data,and rare disease registries and biobanks,which have shaped the structure of the workshops.We discuss the latest insights into making BYODs more productive by leveraging our almost ten years of training experience in these workshops,including successes and encountered challenges.Finally,we examine how the participants'feedback has motivated the research on FAIR,including the development of workflows and software.展开更多
Within this work,we perform a sensitivity analysis to determine the influence of the material input parameters on the pressure in an isotropic porous solid cylinder.We provide a step-by-step guide to obtain the analyt...Within this work,we perform a sensitivity analysis to determine the influence of the material input parameters on the pressure in an isotropic porous solid cylinder.We provide a step-by-step guide to obtain the analytical solution for a porous isotropic elastic cylinder in terms of the pressure,stresses,and elastic displacement.We obtain the solution by performing a Laplace transform on the governing equations,which are those of Biot's poroelasticity in cylindrical polar coordinates.We enforce radial boundary conditions and obtain the solution in the Laplace transformed domain before reverting back to the time domain.The sensitivity analysis is then carried out,considering only the derived pressure solution.This analysis finds that the time t,Biot's modulus M,and Poisson's ratio ν have the highest influence on the pressure whereas the initial value of pressure P_(0) plays a very little role.展开更多
Early-stage fire-warning systems(EFWSs)have attracted significant attention owing to their superiority in detecting fire situations occurring in the pre-combustion process.Substantial progress on EFWSs has been achiev...Early-stage fire-warning systems(EFWSs)have attracted significant attention owing to their superiority in detecting fire situations occurring in the pre-combustion process.Substantial progress on EFWSs has been achieved recently,and they have presented a considerable possibility for more evacuation time to control constant unintentional fire hazards in our daily life.This review mainly makes a comprehensive summary of the current EFWSs,including the working mechanisms and their performance.According to the different working mechanisms,fire alarms can be classified into graphene oxide-based fire alarms,semiconductor-based fire alarms,thermoelectric-based fire alarms,and fire alarms on other working mechanisms.Finally,the challenge and prospect for EFWSs are briefly provided by comparing the art of state of fire alarms.This work can propose a more comprehensive understanding of EFWSs and a guideline for the cutting-edge development direction of EFWSs for readers.展开更多
Cinchona officinalis (Rubiaceae) is an endemic species of the Loja Valley in southern Ecuador with medicinal uses. Because of over-exploitation in the nine- teenth century and more recent disturbances to its ecosyst...Cinchona officinalis (Rubiaceae) is an endemic species of the Loja Valley in southern Ecuador with medicinal uses. Because of over-exploitation in the nine- teenth century and more recent disturbances to its ecosystem, C. officinalis populations are threatened. Currently, natural regeneration of the populations is low, despite its high plant regeneration and seed formation capacity. In the present study, an efficient protocol for germination, shoot proliferation and plantlets regeneration was developed for this species. Phenolic content and germination rate of C. officinalis seeds were compared with a control species, C. pubescens. Nodal segments from seedlings of C. officinalis were cultured on Gamborg medium supplemented with different combinations of plant growth regulators. Because the phenol content is high in C. officinalis, the phenolic should be removed with hydrogen peroxide or water washes to stimulate germination. Shoots and callus developed from nodal segments within 45 days using most of the tested combinations of plant growth regulators. The best rates of shoot proliferation, callus formation and adventitious buds were obtained in medium supplemented with 5.0 mg L^-1 6-benzyl-aminopurine and 3.0 mg L^-1 indole- 3-butyfic acid.展开更多
This work investigates the effect of solid solution on ductility and on the activation of individual deformation mechanisms at moderate temperatures and at quasi-static strain rates in Mg-Zn and Mg-Al alloys. With tha...This work investigates the effect of solid solution on ductility and on the activation of individual deformation mechanisms at moderate temperatures and at quasi-static strain rates in Mg-Zn and Mg-Al alloys. With that aim, four solid solution Mg-Zn and Mg-Al binary alloy ingots containing 1 and 2 wt.% solute atoms were subjected to hot rolling and subsequent annealing to generate polycrystals with similar average grain size and basal-type texture for each composition. The activity of the different slip systems after tensile testing at 150°C and at 250°C was evaluated in pure Mg and in the alloys by EBSD-assisted slip trace analysis. In addition, segregation of Zn and Al atoms at grain boundaries during the thermo-mechanical processing was characterized by HAADF-STEM and EDX. It was found that while the addition of Al and Zn atoms to pure Mg does not lead to major changes in the mechanical strength at the investigated temperatures, it does enhance ductility significantly, especially at 250℃. Our results show that this increase in ductility cannot be attributed to a higher activation of non-basal systems in the alloys, as reported earlier, as the incidence of non-basal systems is indeed considerably higher in pure Mg. This work suggests, on the contrary, that the ductility increase may be attributed to the presence of a more homogenous basal activity in the alloys due to a lower degree of orientation clustering, to grain boundary solute segregation, and to a higher slip diffusivity at grain interiors.展开更多
Proton generation,transport and interaction with hollow cone targets are investigated by means of two-dimensional PIC simulations.A scaled-down hollow cone with gold walls,a carbon tip and a curved hydrogen foil insid...Proton generation,transport and interaction with hollow cone targets are investigated by means of two-dimensional PIC simulations.A scaled-down hollow cone with gold walls,a carbon tip and a curved hydrogen foil inside the cone has been considered.Proton acceleration is driven by a 10^(20) W·cm^(-2) and 1 ps laser pulse focused on the hydrogen foil.Simulations show an important surface current at the cone walls which generates a magnetic field.This magnetic field is dragged by the quasi-neutral plasma formed by fast protons and co-moving electrons when they propagate towards the cone tip.As a result,a tens of kT B z field is set up at the cone tip,which is strong enough to deflect the protons and increase the beam divergence substantially.We propose using heavy materials at the cone tip and increasing the laser intensity in order to mitigate magnetic field generation and proton beam divergence.展开更多
We present the first simulation results of a multi-shell target ignition driven by Z-pinch dynamic hohlraum radiation pulse.The radiation pulse is produced with a special Z-pinch dynamic hohlraum configuration,where t...We present the first simulation results of a multi-shell target ignition driven by Z-pinch dynamic hohlraum radiation pulse.The radiation pulse is produced with a special Z-pinch dynamic hohlraum configuration,where the hohlraum is composed of a single metal liner,a low-Z plastic foam,and a high-Z metallic foam.The implosion dynamics of a hohlraum and a multi-shell target are investigated separately by the one-dimensional code MULTI-IFE.When the peak drive current is 50 MA,simulations suggest that an x-ray pulse with nearly constant radiation temperature(-310 eV)and a duration about 9 ns can be obtained.A small multi-shell target with a radius of 1.35 mm driven by this radiation pulse is able to achieve volumetric ignition with an energy gain(G)about 6.19,where G is the ratio of the yield to the absorbed radiation.Through this research,we better understand the effects of non-uniformities and hydrodynamics instabilities in Z-pinch dynamic hohlraum.展开更多
Background: Increased peak oxygen consumption(VO2 peak) can reduce cardiovascular risks associated with obesity. Our aim was to analyze the effect of a weight loss program on cardiovascular fitness in overweight(W) an...Background: Increased peak oxygen consumption(VO2 peak) can reduce cardiovascular risks associated with obesity. Our aim was to analyze the effect of a weight loss program on cardiovascular fitness in overweight(W) and obese(O) subjects.Methods: One hundred and sixty-seven subjects(77 males and 90 females), aged 18–50 years, performed a modified Bruce protocol before(pre)and after(post) a weight loss program of 24 weeks. This program combined physical training(strength, S; endurance, E; combined strength + endurance, SE; or physical activity recommendation, PA) 3 times per week, with a 25%–30% caloric restriction diet.Results: VO2 peak improved in overweight and obese males(pre and post values in L/min, respectively; W = 3.2 ± 0.6 vs. 3.7 ± 0.5, p < 0.001;O = 3.6 ± 0.6 vs. 3.8 ± 0.6, p = 0.013) as well as in overweight females(2.0 ± 0.3 vs. 2.3 ± 0.4, p < 0.001). VO2 peak in the first ventilatory threshold(VT1) increased for all 4 interventions in males(p < 0.05), except for S in the obese group(1.6 ± 0.2 vs. 1.7 ± 0.3, p = 0.141). In females, it increased in E(0.9 ± 0.2 vs. 1.4 ± 0.3, p < 0.001), SE(0.9 ± 0.2 vs. 1.2 ± 0.4, p = 0.003), and PA(0.9 ± 0.1 vs. 1.2 ± 0.2, p = 0.006) in overweight groups. Time-to-exhaustion improved in all subjects except for females in PA group(15.7 ± 0.3 min vs. 15.9 ± 0.3 min, p = 0.495).Conclusion: Our results suggest that all methods, including the recommendation of physical activity, can improve cardiovascular fitness in overweight subjects and obese males.展开更多
A series of liner-like Z-pinch loads with a novel configuration have been investigated experimentally for the first time on Qiangguang-I facility in China.The metallic layer is sputtered on the inner surface of the cy...A series of liner-like Z-pinch loads with a novel configuration have been investigated experimentally for the first time on Qiangguang-I facility in China.The metallic layer is sputtered on the inner surface of the cylindrical SiO 2 substrate tube.In the preliminary experiment,the electric current flowed through the metallic load during the prepulse.However,the currents also flowed through the outer surface of the SiO 2 substrate during the main pulse.After the dielectric length had been increased in the formal experiment,most of the current flowed through the metallic load until radial radiation peak was measured by radiation monitor.As the line mass of the metallic load increases,the peak time of radial radiation also increases.Axial ultravi-olet frames indicate that the radiations are nearly azi-muthally uniform at first,but the uniformity becomes worse after radial radiation peak.The clearly separated boundary between the metal plasmas and the substrate has not been observed in the experiment.Experimental results are discussed and compared with simulation using the one-dimension radiation hydrodynamics code MULTI-IFE.展开更多
基金This study was funded by projects“Vulnerabilidad y resiliencia de bosques maduros de Quercus mediterraneos en espacios protegidos bajo diferentes escenarios climaticos y de gestion(QuMature)”(Ref.PRCV00594,Fundacion Biodiversidad)TED 2021-129770 B-C21(Spanish Ministry of Science and Innovation)FC was supported by the Portuguese R&D unit CFE(FCT/UIDB/04004/2020).
文摘Different leaf(evergreen vs.deciduous habit)and xylem(diffuse-vs.ring-porous wood)traits represent contrasting strategies to face seasonal changes in water availability and temperature.However,how contrasting leaf and xylem habits of coexisting tree species affect stem wood formation and tree-ring development remains poorly understood.Here,we investigated the spatio-temporal patterns of wood formation in two deciduous oaks(Quercus faginea and Quercus petraea)and two evergreen oaks(Quercus ilex and Quercus suber)coexisting in seasonally dry Mediterranean forests along an aridity gradient in Spain.We hypothesized that growth responses to drought and intra-and inter-annual growth patterns would differ between functional groups.We simulated intra-and interannual growth using a modified version of the Vaganov-Shashkin(VS)process-based,growth model.The VS model simulations were used to estimate growth changes under a high emission scenario(RCP 8.5)for the current distribution of the study oak species and to forecast their future performance under warm(4.8℃)conditions in the Iberian Peninsula.Our simulations indicate that climate warming would induce a shortening of the ringgrowth season and a reduction of radial growth in evergreen and deciduous Mediterranean oaks,particularly in dry sites from southern and eastern Iberia currently occupied by Q.ilex and Q.faginea.Evergreen oaks may better recover after dry periods than deciduous oaks by resuming growth after the summer drought.Low soil water availability in spring would be more detrimental to growth of deciduous oaks.Process-based growth models should be refined and validated to better forecast changes in tree growth as a function of climate.
基金support by project SUPERB H2020(Systemic solutions for upscaling of urgent ecosystem restoration for forest related biodiversity and ecosystem services)support by project P2013/MAE-2760(Autonomous Community of Madrid)+3 种基金support by project PID2019-107256RB-I00(Spanish Ministry of Science and Innovation)project FAGUS by the Comunidad de Madrid through the call Research Grants for Young Investigators from Universidad Polit ecnica de Madridsupport by projects 9OHUU0-10-3L226X(Autonomous Community of Madrid)RTI2018-094202-BC21 and RTI2018-094202-A-C22(Spanish Ministry of Science and Innovation)。
文摘There is an increasing interest in restoring degraded forests,which occupy half of the forest areas.Among the forms of restoration,passive restoration,which involves the elimination of degrading factors and the free evolution of natural dynamics by applying minimal or no management,is gaining attention.Natural dynamics is difficult to predict due to the influence of multiple interacting factors such as climatic and edaphic conditions,composition and abundance of species,and the successional character of these species.Here,we study the natural dynamics of a mixed forest located in central Spain,which maintained an open forest structure,due to intensive use,until grazing and cutting were banned in the 1960s.The most frequent woody species in this forest are Fagus sylvatica,Quercus petraea,Quercus pyrenaica,Ilex aquifolium,Sorbus aucuparia,Sorbus aria and Prunus avium,with contrasting shade and drought tolerance.These species are common in temperate European deciduous forest and are found here near their southern distribution limit,except for Q.pyrenaica.In order to analyze forest dynamics and composition,three inventories were carried out in 1994,2005 and 2015.Our results show that,despite the Mediterranean influence,the natural dynamics of this forest has been mainly determined by different levels of shade tolerance.After the abandonment of grazing and cutting,Q.pyrenaica expanded rapidly due to its lower shade tolerance,whereas after canopy closure and forest densification,shade-tolerant species gained ground,particularly F.sylvatica,despite its lower drought and late-frost tolerance.If the current dynamics continue,F.sylvatica will overtake the rest of the species,which will be relegated to sites with shallow soils and steep slopes.Simultaneously,all the multi-centennial beech trees,which are undergoing a rapid mortality and decline process,will disappear.
文摘This paper proposes a methodology for the quantitative robustness evaluation of PID controllers employed in a DC motor. The robustness analysis is performed employing a 2~3 factorial experimental design for a fractional order proportional integral and derivative controller(FOPID), integer order proportional integral and derivative controller(IOPID)and the Skogestad internal model control controller(SIMC). The factors assumed in experiment are the presence of random noise,external disturbances in the system input and variable load. As output variables, the experimental design employs the system step response and the controller action. Practical implementation of FOPID and IOPID controllers uses the MATLAB stateflow toolbox and a NI data acquisition system. Results of the robustness analysis show that the FOPID controller has a better performance and robust stability against the experiment factors.
基金Supported by the National Natural Science Foundation of China(No.60830001)Program for New Century Excellent Talents in University(No.NCET-09-0206)+2 种基金the Key Project of State Key Lab.of Rail Traffic Control and Safety(No.RCS2008ZZ006)Program for Changjiang Scholars and Innovative Research Team in University(No.IRT0949)the Project of State Key Lab.of Rail Traffic Control and Safety(No.RCS2008ZT005)
文摘Communication based train control systems(CBTC) must work even in the worst situation—train crossing.This paper models the propagation characteristics in one of the most common and pivotal scenarios—train crossing in subway tunnels which is rarely mentioned in previous publications.Firsdy,measurements for train crossing scenario at 2.4 GHz in a real subway line in Madrid have been made.The field measurement is the most reliable way to reveal the propagation characteristics involving shadowing effect and fast fading.Moreover,to precisely describe the fast fading distribution and eliminate the inevitable weak points of traditional fitting way,a best numerical approximation method using Legendre orthogonal polynomials has been proposed.Comparisons show that this method works better and is of greater physical significance.Finally,a complete statistical model is given and all the coefficients can be applied by system designers for the link and system level simulations.
基金supported by the Spanish Ministry of Economy and Competitiveness(grant numbers AGL2010-21929 and AGL2013-48756-R)the Spanish Ministry of Economy and Competitiveness,the Agencia Estatal de Investigación,and the European Regional Development Fund(grant number AGL2016–80967-R)Government of Aragon(Research Group A08_20R)。
文摘Response to vernalization and photoperiod are the main determinants controlling the time to flowering in temperate cereals. While the individual genes that determine a plant's response to these environmental signals are well characterized, the combinatorial effect on flowering time of allelic variants for multiple genes remains unresolved. This study investigated the genetic control of flowering-time in a biparental population of spring barley, derived from a wide cross between a late-flowering European and an early-flowering North-American cultivar. While the major flowering time genes are not segregating in the Beka ×Logan cross, large variation in flowering was observed. We identified five QTL, with both parents found to contribute early alleles. The catalog of QTL discovered aligns with several candidate genes affecting flowering time in barley. The combination of particular alleles at HvCEN, HvELF3 and HvFT1 in Logan are responsible for the earliness of this cultivar. Interestingly, earliness for flowering could be further enhanced, with Beka found to contribute three early alleles, including a QTL colocating with a HvFD-like gene, suggesting that there are diverse aspects of the flowering-time pathway that have been manipulated in these two cultivars. Epistatic interactions between flowering-time QTL or candidate genes were observed in field data and confirmed under controlled conditions. The results of this study link photoperiod-dependent flowering-time genes with earliness per se genes into a single model, thus providing a unique framework that can be used by geneticists and breeders to optimize flowering time in barley.
文摘Background Genotype-by-sequencing has been proposed as an alternative to SNP genotyping arrays in genomic selection to obtain a high density of markers along the genome.It requires a low sequencing depth to be cost effective,which may increase the error at the genotype assigment.Third generation nanopore sequencing technology offers low cost sequencing and the possibility to detect genome methylation,which provides added value to genotype-by-sequencing.The aim of this study was to evaluate the performance of genotype-by-low pass nanopore sequencing for estimating the direct genomic value in dairy cattle,and the possibility to obtain methylation marks simultaneously.Results Latest nanopore chemistry(LSK14 and Q20)achieved a modal base calling accuracy of 99.55%,whereas previous kit(LSK109)achieved slightly lower accuracy(99.1%).The direct genomic value accuracy from genotype-by-low pass sequencing ranged between 0.79 and 0.99,depending on the trait(milk,fat or protein yield),with a sequencing depth as low as 2×and using the latest chemistry(LSK114).Lower sequencing depth led to biased estimates,yet with high rank correlations.The LSK109 and Q20 achieved lower accuracies(0.57-0.93).More than one million high reliable methylated sites were obtained,even at low sequencing depth,located mainly in distal intergenic(87%)and promoter(5%)regions.Conclusions This study showed that the latest nanopore technology in useful in a LowPass sequencing framework to estimate direct genomic values with high reliability.It may provide advantages in populations with no available SNP chip,or when a large density of markers with a wide range of allele frequencies is needed.In addition,low pass sequencing provided nucleotide methylation status of>1 million nucleotides at≥10×,which is an added value for epigenetic studies.
基金The publication is produced within the framework of Ramon Alcarria y Borja Bordel’s research projects on the occasion of their stay at Argonne Labs(Jose Castillejo’s 2021 grant)supported by the Ministry of Science,Innovation andUniversities through the COGNOS project.
文摘Future components to enhance the basic,native security of 5G networks are either complex mechanisms whose impact in the requiring 5G communications are not considered,or lightweight solutions adapted to ultrareliable low-latency communications(URLLC)but whose security properties remain under discussion.Although different 5G network slices may have different requirements,in general,both visions seem to fall short at provisioning secure URLLC in the future.In this work we address this challenge,by introducing cost-security functions as a method to evaluate the performance and adequacy of most developed and employed non-native enhanced security mechanisms in 5G networks.We categorize those new security components into different groups according to their purpose and deployment scope.We propose to analyze them in the context of existing 5G architectures using two different approaches.First,using model checking techniques,we will evaluate the probability of an attacker to be successful against each security solution.Second,using analytical models,we will analyze the impact of these security mechanisms in terms of delay,throughput consumption,and reliability.Finally,we will combine both approaches using stochastic cost-security functions and the PRISM model checker to create a global picture.Our results are first evidence of how a 5G network that covers and strengthened all security areas through enhanced,dedicated non-native mechanisms could only guarantee secure URLLC with a probability of∼55%.
基金support from the RD-Connect project(funded from the European Community's Seventh Framework Program under grant agreement n°305444"RD-CONNECT")ELIXIR and ELIXIR-EXCELERATE(Grant number EU H2020#676559)+1 种基金the Istituto Superiore di Sanita(ISS),the Leiden University Medical Center(LUMC)the University Medical Center Groningen,and the Dutch Techcentre for Life Sciences(DTL)between 2014 and 2018.From 2019 to 2023,the RD-BYOD has been funded by the European Joint Programme Rare Diseases(EJP RD)and its partners(European Union Horizon 2020 Research and Innovation Programme under Grant Agreement n°825575),and we are grateful for their continued support.
文摘Since 2014,"Bring Your Own Data"workshops(BYODs)have been organised to inform people about the process and benefits of making resources Findable,Accessible,Interoperable,and Reusable(FAIR,and the FAIRification process).The BYOD workshops'content and format differ depending on their goal,context,and the background and needs of participants.Data-focused BYODs educate domain experts on how to make their data FAIR to find new answers to research questions.Management-focused BYODs promote the benefits of making data FAIR and instruct project managers and policy-makers on the characteristics of FAIRification projects.Software-focused BYODs gather software developers and experts on FAIR to implement or improve software resources that are used to support FAIRification.Overall,these BYODs intend to foster collaboration between different types of stakeholders involved in data management,curation,and reuse(e.g.domain experts,trainers,developers,data owners,data analysts,FAIR experts).The BYODs also serve as an opportunity to learn what kind of support for FAIRification is needed from different communities and to develop teaching materials based on practical examples and experience.In this paper,we detail the three different structures of the BYODs and describe examples of early BYODs related to plant breeding data,and rare disease registries and biobanks,which have shaped the structure of the workshops.We discuss the latest insights into making BYODs more productive by leveraging our almost ten years of training experience in these workshops,including successes and encountered challenges.Finally,we examine how the participants'feedback has motivated the research on FAIR,including the development of workflows and software.
基金Project supported by the Engineering and Physical Sciences Research Council of U. K.(Nos. EP/S030875/1, EP/T017899/1, and EP/T517896/1)。
文摘Within this work,we perform a sensitivity analysis to determine the influence of the material input parameters on the pressure in an isotropic porous solid cylinder.We provide a step-by-step guide to obtain the analytical solution for a porous isotropic elastic cylinder in terms of the pressure,stresses,and elastic displacement.We obtain the solution by performing a Laplace transform on the governing equations,which are those of Biot's poroelasticity in cylindrical polar coordinates.We enforce radial boundary conditions and obtain the solution in the Laplace transformed domain before reverting back to the time domain.The sensitivity analysis is then carried out,considering only the derived pressure solution.This analysis finds that the time t,Biot's modulus M,and Poisson's ratio ν have the highest influence on the pressure whereas the initial value of pressure P_(0) plays a very little role.
基金open project(No.47549P0)of the State Key Laboratory of Scientific and Engineering Computing,Chinese Academy of SciencesNational Natural Science Foundation of China(Grant No.10872037)+2 种基金Natural Science Research Project of Henan Province(Grant No.2009A110017)Ministerio de Educación y Ciencia(Spain)(grant MTM2005-05573)Sabbatical Program(SAB2006-0070)of the Spanish Ministry of Education and Science
基金This work was partially supported by the China Scholarship Council under the Grant CSC(201908110272)BIOFIRESAFE Project funded by Ministerio De Ciencia E Innovacion,Spain,with the project numbers:PID2020-117274RB-I00BIOFIRESAFE and PEJ-2018 MINECO.
文摘Early-stage fire-warning systems(EFWSs)have attracted significant attention owing to their superiority in detecting fire situations occurring in the pre-combustion process.Substantial progress on EFWSs has been achieved recently,and they have presented a considerable possibility for more evacuation time to control constant unintentional fire hazards in our daily life.This review mainly makes a comprehensive summary of the current EFWSs,including the working mechanisms and their performance.According to the different working mechanisms,fire alarms can be classified into graphene oxide-based fire alarms,semiconductor-based fire alarms,thermoelectric-based fire alarms,and fire alarms on other working mechanisms.Finally,the challenge and prospect for EFWSs are briefly provided by comparing the art of state of fire alarms.This work can propose a more comprehensive understanding of EFWSs and a guideline for the cutting-edge development direction of EFWSs for readers.
基金the project‘‘PROY_IECOLOGIA_0036’’financed by the third internal call for projects of the Universidad Tcnica Particular de Loja(UTPL)
文摘Cinchona officinalis (Rubiaceae) is an endemic species of the Loja Valley in southern Ecuador with medicinal uses. Because of over-exploitation in the nine- teenth century and more recent disturbances to its ecosystem, C. officinalis populations are threatened. Currently, natural regeneration of the populations is low, despite its high plant regeneration and seed formation capacity. In the present study, an efficient protocol for germination, shoot proliferation and plantlets regeneration was developed for this species. Phenolic content and germination rate of C. officinalis seeds were compared with a control species, C. pubescens. Nodal segments from seedlings of C. officinalis were cultured on Gamborg medium supplemented with different combinations of plant growth regulators. Because the phenol content is high in C. officinalis, the phenolic should be removed with hydrogen peroxide or water washes to stimulate germination. Shoots and callus developed from nodal segments within 45 days using most of the tested combinations of plant growth regulators. The best rates of shoot proliferation, callus formation and adventitious buds were obtained in medium supplemented with 5.0 mg L^-1 6-benzyl-aminopurine and 3.0 mg L^-1 indole- 3-butyfic acid.
基金funding from the Madrid region under programme S2018/NMT4381-MAT4.0-CM projectFunding from projects PID2019111285RB-I00 and PID2020-118626RB-I00 awarded by the Spanish Ministry of Science, Innovation and Universitiesfinancial support from the China Scholarship Council (Grant no 201706050154)
文摘This work investigates the effect of solid solution on ductility and on the activation of individual deformation mechanisms at moderate temperatures and at quasi-static strain rates in Mg-Zn and Mg-Al alloys. With that aim, four solid solution Mg-Zn and Mg-Al binary alloy ingots containing 1 and 2 wt.% solute atoms were subjected to hot rolling and subsequent annealing to generate polycrystals with similar average grain size and basal-type texture for each composition. The activity of the different slip systems after tensile testing at 150°C and at 250°C was evaluated in pure Mg and in the alloys by EBSD-assisted slip trace analysis. In addition, segregation of Zn and Al atoms at grain boundaries during the thermo-mechanical processing was characterized by HAADF-STEM and EDX. It was found that while the addition of Al and Zn atoms to pure Mg does not lead to major changes in the mechanical strength at the investigated temperatures, it does enhance ductility significantly, especially at 250℃. Our results show that this increase in ductility cannot be attributed to a higher activation of non-basal systems in the alloys, as reported earlier, as the incidence of non-basal systems is indeed considerably higher in pure Mg. This work suggests, on the contrary, that the ductility increase may be attributed to the presence of a more homogenous basal activity in the alloys due to a lower degree of orientation clustering, to grain boundary solute segregation, and to a higher slip diffusivity at grain interiors.
基金This work has been partially supported by the grant numberENE2014-54960-R of the Spanish Ministry of Economy andCompetitivenessthe COST Action MP1208 and the Co-ordinated Research Project of IAEA F13016.
文摘Proton generation,transport and interaction with hollow cone targets are investigated by means of two-dimensional PIC simulations.A scaled-down hollow cone with gold walls,a carbon tip and a curved hydrogen foil inside the cone has been considered.Proton acceleration is driven by a 10^(20) W·cm^(-2) and 1 ps laser pulse focused on the hydrogen foil.Simulations show an important surface current at the cone walls which generates a magnetic field.This magnetic field is dragged by the quasi-neutral plasma formed by fast protons and co-moving electrons when they propagate towards the cone tip.As a result,a tens of kT B z field is set up at the cone tip,which is strong enough to deflect the protons and increase the beam divergence substantially.We propose using heavy materials at the cone tip and increasing the laser intensity in order to mitigate magnetic field generation and proton beam divergence.
基金Project supported by the Science Challenge Project (Grant No. TZ2018001)the Strategic Priority Research Program of the Chinese Academy of Sciences(Grant Nos. XDA25051200 and XDA25050200)+4 种基金the National Natural Science Foundation of China (Grant Nos. 11705282 and 11775305)Hunan Graduate Scientific Research Innovation Project (Grant No. CX20190001)supported by the spanish “Ministerio de Ciencia Innovación y Universidades”project RTI2018-098801-B-100the Spanish “Ministerio de Economía y Competitividad” Project ENE2014-54960-Rthe EURO fusion Consortium project AWP15-ENR-01/CEA-02
文摘We present the first simulation results of a multi-shell target ignition driven by Z-pinch dynamic hohlraum radiation pulse.The radiation pulse is produced with a special Z-pinch dynamic hohlraum configuration,where the hohlraum is composed of a single metal liner,a low-Z plastic foam,and a high-Z metallic foam.The implosion dynamics of a hohlraum and a multi-shell target are investigated separately by the one-dimensional code MULTI-IFE.When the peak drive current is 50 MA,simulations suggest that an x-ray pulse with nearly constant radiation temperature(-310 eV)and a duration about 9 ns can be obtained.A small multi-shell target with a radius of 1.35 mm driven by this radiation pulse is able to achieve volumetric ignition with an energy gain(G)about 6.19,where G is the ratio of the yield to the absorbed radiation.Through this research,we better understand the effects of non-uniformities and hydrodynamics instabilities in Z-pinch dynamic hohlraum.
基金financial support of the Ministerio de Ciencia e Innovación, Convocatoria deAyudas I + D 2008, Proyectos de Investigación Fundamental No Orientada, del VI Plan de Investigación Nacional 2008– 2011 (contract: DEP2008-06354-C04-01)EAC is funded by a predoctoral grant from the Coordination for the Improvement of Higher Education Personnel (CAPES)
文摘Background: Increased peak oxygen consumption(VO2 peak) can reduce cardiovascular risks associated with obesity. Our aim was to analyze the effect of a weight loss program on cardiovascular fitness in overweight(W) and obese(O) subjects.Methods: One hundred and sixty-seven subjects(77 males and 90 females), aged 18–50 years, performed a modified Bruce protocol before(pre)and after(post) a weight loss program of 24 weeks. This program combined physical training(strength, S; endurance, E; combined strength + endurance, SE; or physical activity recommendation, PA) 3 times per week, with a 25%–30% caloric restriction diet.Results: VO2 peak improved in overweight and obese males(pre and post values in L/min, respectively; W = 3.2 ± 0.6 vs. 3.7 ± 0.5, p < 0.001;O = 3.6 ± 0.6 vs. 3.8 ± 0.6, p = 0.013) as well as in overweight females(2.0 ± 0.3 vs. 2.3 ± 0.4, p < 0.001). VO2 peak in the first ventilatory threshold(VT1) increased for all 4 interventions in males(p < 0.05), except for S in the obese group(1.6 ± 0.2 vs. 1.7 ± 0.3, p = 0.141). In females, it increased in E(0.9 ± 0.2 vs. 1.4 ± 0.3, p < 0.001), SE(0.9 ± 0.2 vs. 1.2 ± 0.4, p = 0.003), and PA(0.9 ± 0.1 vs. 1.2 ± 0.2, p = 0.006) in overweight groups. Time-to-exhaustion improved in all subjects except for females in PA group(15.7 ± 0.3 min vs. 15.9 ± 0.3 min, p = 0.495).Conclusion: Our results suggest that all methods, including the recommendation of physical activity, can improve cardiovascular fitness in overweight subjects and obese males.
基金supported by National Natural Science Foundation of China(No.11805175).
文摘A series of liner-like Z-pinch loads with a novel configuration have been investigated experimentally for the first time on Qiangguang-I facility in China.The metallic layer is sputtered on the inner surface of the cylindrical SiO 2 substrate tube.In the preliminary experiment,the electric current flowed through the metallic load during the prepulse.However,the currents also flowed through the outer surface of the SiO 2 substrate during the main pulse.After the dielectric length had been increased in the formal experiment,most of the current flowed through the metallic load until radial radiation peak was measured by radiation monitor.As the line mass of the metallic load increases,the peak time of radial radiation also increases.Axial ultravi-olet frames indicate that the radiations are nearly azi-muthally uniform at first,but the uniformity becomes worse after radial radiation peak.The clearly separated boundary between the metal plasmas and the substrate has not been observed in the experiment.Experimental results are discussed and compared with simulation using the one-dimension radiation hydrodynamics code MULTI-IFE.