AIM: To investigate the effect of the probiotic combination Lactibiane Tolerance<sup>®</sup> (LT) on epithelial barrier function in vitro and in vivo.
The unsteady oscillatory flow of an incompressible second grade fluid in a cylindrical tube with large wall suction is studied analytically. Flow in the tube is due to uniform suction at the permeable walls, and the o...The unsteady oscillatory flow of an incompressible second grade fluid in a cylindrical tube with large wall suction is studied analytically. Flow in the tube is due to uniform suction at the permeable walls, and the oscillations in the velocity field are due to small amplitude time harmonic pressure waves. The physical quantities of interest are the velocity field, the amplitude of oscillation, and the penetration depth of the oscillatory wave. The analytical solution of the governing boundary value problem is obtained, and the effects of second grade fluid parameters are analyzed and discussed.展开更多
We present new,geological,metamorphic,geochemical and geochronological data on the East Anatolian-Lesser Caucasus ophiolites.These data are used in combination with a synthesis of previous data and numerical modelling...We present new,geological,metamorphic,geochemical and geochronological data on the East Anatolian-Lesser Caucasus ophiolites.These data are used in combination with a synthesis of previous data and numerical modelling to unravel the tectonic emplacement of ophiolites in this region.All these data allow the reconstruction of a large obducted ophiolite nappe,thrusted for>100 km and up to 250 km on the Anatolian-Armenian block.The ophiolite petrology shows three distinct magmatic series,highlighted by new isotopic and trace element data:(1)The main Early Jurassic Tholeiites(ophiolite s.s.)bear LILEenriched,subduction-modified,MORB chemical composition.Geology and petrology of the Tholeiite series substantiates a slow-spreading oceanic environment in a time spanning from the Late Triassic to the Middle-Late Jurassic.Serpentinites,gabbros and plagiogranites were exhumed by normal faults,and covered by radiolarites,while minor volumes of pillow-lava flows infilled the rift grabens.Tendency towards a subduction-modified geochemical signature suggests emplacement in a marginal basin above a subduction zone.(2)Late Early Cretaceous alkaline lavas conformably emplaced on top of the ophiolite.They have an OIB affinity.These lavas are featured by large pillow lavas interbedded a carbonate matrix.They show evidence for a large-scale OIB plume activity,which occurred prior to ophiolite obduction.(3)Early-Late Cretaceous calc-alkaline lavas and dykes.These magmatic rocks are found on top of the obducted nappe,above the post-obduction erosion level.This series shows similar Sr-Nd isotopic features as the Alkaline series,though having a clear supra-subduction affinity.They are thus interpreted to be the remelting product of a mantle previously contaminated by the OIB plume.Correlation of data from the Lesser Caucasus to western Anatolia shows a progression from back-arc to arc and fore-arc,which highlight a dissymmetry in the obducted oceanic lithosphere from East to West.The metamorphic P-T-t paths of the obduction sole lithologies define a southward propagation of the ophiolite:(1)P-T-t data from the northern Sevan-Akera suture zone(Armenia)highlight the presence and exhumation of eclogites(1.85±0.02 GPa and 590±5℃)and blueschists below the ophiolite,which are dated at ca.94 Ma by Ar-Ar on phengite.(2)Neighbouring Amasia(Armenia)garnet amphibolites indicate metamorphic peak conditions of 0.65±0.05 GPa and 600±20 C with a U-Pb on rutile age of 90.2±5.2 Ma and Ar-Ar on amphibole and phengite ages of 90.8±3.0 Ma and 90.8±1.2 Ma,respectively.These data are consistent with palaeontological dating of sediment deposits directly under(Cenomanian,i.e.>93.9 Ma)or sealing(Coniacian-Santonian,i.e.,≤89.8 Ma),the obduction.(3)At Hinis(NE Turkey)PT-t conditions on amphibolites(0.66±0.06 GPa and 660±20℃,with a U-Pb titanite age of80.0±3.2 Ma)agree with previous P-T-t data on granulites,and highlight a rapid exhumation below a top-to-the-North detachment sealed by the Early Maastrichtian unconformity(ca.70.6 Ma).Amphibolites are cross-cut by monzonites dated by U-Pb on titanite at 78.3±3.7 Ma.We propose that the HT-MP metamorphism was coeval with the monzonites,about 10 Ma after the obduction,and was triggered by the onset of subduction South of the Anatolides and by reactivation or acceleration of the subduction below the Pontides-Eurasian margin.Numerical modelling accounts for the obduction of an"old"~80 Myr oceanic lithosphere due to a significant heating of oceanic lithosphere through mantle upwelling,which increased the oceanic lithosphere buoyancy.The long-distance transport of a currently thin section of ophiolites(<1 km)onto the Anatolian continental margin is ascribed to a combination of northward mantle extensional thinning of the obducted oceanic lithosphere by the Hinis detachment at ca.80 Ma,and southward gravitational propagation of the ophiolite nappe onto its foreland basin.展开更多
Analytical solutions for the peristaltic flow of a magneto hydrodynamic （MHD） Sisko fluid in a channel, under the effects of strong and weak magnetic fields, are presented. The governing nonlinear problem, for the s...Analytical solutions for the peristaltic flow of a magneto hydrodynamic （MHD） Sisko fluid in a channel, under the effects of strong and weak magnetic fields, are presented. The governing nonlinear problem, for the strong magnetic field, is solved using the matched asymptotic expansion. The solution for the weak magnetic field is obtained using a regular perturbation method. The main observation is the existence of a Hartman boundary layer for the strong magnetic field at the location of the two plates of the channel. The thickness of the Hartmann boundary layer is determined analytically. The effects of a strong magnetic field and the shear thinning parameter of the Sisko fluid on the velocity profile are presented graphically.展开更多
Purpose： This study aimed to investigate whether workload intensity modulates exercise-induced effect on reaction time （RT） performances, and more specifically to clarify whether cognitive control that plays a cruc...Purpose： This study aimed to investigate whether workload intensity modulates exercise-induced effect on reaction time （RT） performances, and more specifically to clarify whether cognitive control that plays a crucial role in rapid decision making is altered. Methods： Fourteen participants performed a Simon Task while cycling 20 min at a light （first ventilatory threshold, VT~ - 20%）, moderate （VTI）, or very hard （VTj ＋ 20%） level of exercise. Results： After 15 min of cycling, RTs are faster than during the first 5 min of exercise. This benefit does not fluctuate with the intensity of exercise and enlarges as RT lengthens. Despite a numerical difference suggesting a greater facilitation during moderate exercise （-16 ms） than during a light exercise （-10 ms）, the benefit is not statistically different. Interestingly, we did not observe any signs of worsening on RT or on accuracy during very hard exercise. Conclusion： Cognitive control is extremely robust and appears not to be affected by the intensity of exercise. The selective inhibition and the between-trials adjustments are effective from the beginning to the end of exercise, regardless of the workload output.展开更多
基金Supported by PiLeJe,37,quai-de-Grenelle,batiment Pollux,75738 Paris cedex 15
文摘AIM: To investigate the effect of the probiotic combination Lactibiane Tolerance<sup>®</sup> (LT) on epithelial barrier function in vitro and in vivo.
文摘The unsteady oscillatory flow of an incompressible second grade fluid in a cylindrical tube with large wall suction is studied analytically. Flow in the tube is due to uniform suction at the permeable walls, and the oscillations in the velocity field are due to small amplitude time harmonic pressure waves. The physical quantities of interest are the velocity field, the amplitude of oscillation, and the penetration depth of the oscillatory wave. The analytical solution of the governing boundary value problem is obtained, and the effects of second grade fluid parameters are analyzed and discussed.
基金supported by the MEBE (Middle East Basin Evolution) and DARIUS programs jointly supported by a consortium including oil companies,UMPC and the INSU,CNRS.G.Topuz acknowledges TüBITAK grant (#114Y226) for support in field works
文摘We present new,geological,metamorphic,geochemical and geochronological data on the East Anatolian-Lesser Caucasus ophiolites.These data are used in combination with a synthesis of previous data and numerical modelling to unravel the tectonic emplacement of ophiolites in this region.All these data allow the reconstruction of a large obducted ophiolite nappe,thrusted for>100 km and up to 250 km on the Anatolian-Armenian block.The ophiolite petrology shows three distinct magmatic series,highlighted by new isotopic and trace element data:(1)The main Early Jurassic Tholeiites(ophiolite s.s.)bear LILEenriched,subduction-modified,MORB chemical composition.Geology and petrology of the Tholeiite series substantiates a slow-spreading oceanic environment in a time spanning from the Late Triassic to the Middle-Late Jurassic.Serpentinites,gabbros and plagiogranites were exhumed by normal faults,and covered by radiolarites,while minor volumes of pillow-lava flows infilled the rift grabens.Tendency towards a subduction-modified geochemical signature suggests emplacement in a marginal basin above a subduction zone.(2)Late Early Cretaceous alkaline lavas conformably emplaced on top of the ophiolite.They have an OIB affinity.These lavas are featured by large pillow lavas interbedded a carbonate matrix.They show evidence for a large-scale OIB plume activity,which occurred prior to ophiolite obduction.(3)Early-Late Cretaceous calc-alkaline lavas and dykes.These magmatic rocks are found on top of the obducted nappe,above the post-obduction erosion level.This series shows similar Sr-Nd isotopic features as the Alkaline series,though having a clear supra-subduction affinity.They are thus interpreted to be the remelting product of a mantle previously contaminated by the OIB plume.Correlation of data from the Lesser Caucasus to western Anatolia shows a progression from back-arc to arc and fore-arc,which highlight a dissymmetry in the obducted oceanic lithosphere from East to West.The metamorphic P-T-t paths of the obduction sole lithologies define a southward propagation of the ophiolite:(1)P-T-t data from the northern Sevan-Akera suture zone(Armenia)highlight the presence and exhumation of eclogites(1.85±0.02 GPa and 590±5℃)and blueschists below the ophiolite,which are dated at ca.94 Ma by Ar-Ar on phengite.(2)Neighbouring Amasia(Armenia)garnet amphibolites indicate metamorphic peak conditions of 0.65±0.05 GPa and 600±20 C with a U-Pb on rutile age of 90.2±5.2 Ma and Ar-Ar on amphibole and phengite ages of 90.8±3.0 Ma and 90.8±1.2 Ma,respectively.These data are consistent with palaeontological dating of sediment deposits directly under(Cenomanian,i.e.>93.9 Ma)or sealing(Coniacian-Santonian,i.e.,≤89.8 Ma),the obduction.(3)At Hinis(NE Turkey)PT-t conditions on amphibolites(0.66±0.06 GPa and 660±20℃,with a U-Pb titanite age of80.0±3.2 Ma)agree with previous P-T-t data on granulites,and highlight a rapid exhumation below a top-to-the-North detachment sealed by the Early Maastrichtian unconformity(ca.70.6 Ma).Amphibolites are cross-cut by monzonites dated by U-Pb on titanite at 78.3±3.7 Ma.We propose that the HT-MP metamorphism was coeval with the monzonites,about 10 Ma after the obduction,and was triggered by the onset of subduction South of the Anatolides and by reactivation or acceleration of the subduction below the Pontides-Eurasian margin.Numerical modelling accounts for the obduction of an"old"~80 Myr oceanic lithosphere due to a significant heating of oceanic lithosphere through mantle upwelling,which increased the oceanic lithosphere buoyancy.The long-distance transport of a currently thin section of ophiolites(<1 km)onto the Anatolian continental margin is ascribed to a combination of northward mantle extensional thinning of the obducted oceanic lithosphere by the Hinis detachment at ca.80 Ma,and southward gravitational propagation of the ophiolite nappe onto its foreland basin.
文摘Analytical solutions for the peristaltic flow of a magneto hydrodynamic （MHD） Sisko fluid in a channel, under the effects of strong and weak magnetic fields, are presented. The governing nonlinear problem, for the strong magnetic field, is solved using the matched asymptotic expansion. The solution for the weak magnetic field is obtained using a regular perturbation method. The main observation is the existence of a Hartman boundary layer for the strong magnetic field at the location of the two plates of the channel. The thickness of the Hartmann boundary layer is determined analytically. The effects of a strong magnetic field and the shear thinning parameter of the Sisko fluid on the velocity profile are presented graphically.
基金supported by a grant from the French Research Agency (ANR 2013-069)
文摘Purpose： This study aimed to investigate whether workload intensity modulates exercise-induced effect on reaction time （RT） performances, and more specifically to clarify whether cognitive control that plays a crucial role in rapid decision making is altered. Methods： Fourteen participants performed a Simon Task while cycling 20 min at a light （first ventilatory threshold, VT~ - 20%）, moderate （VTI）, or very hard （VTj ＋ 20%） level of exercise. Results： After 15 min of cycling, RTs are faster than during the first 5 min of exercise. This benefit does not fluctuate with the intensity of exercise and enlarges as RT lengthens. Despite a numerical difference suggesting a greater facilitation during moderate exercise （-16 ms） than during a light exercise （-10 ms）, the benefit is not statistically different. Interestingly, we did not observe any signs of worsening on RT or on accuracy during very hard exercise. Conclusion： Cognitive control is extremely robust and appears not to be affected by the intensity of exercise. The selective inhibition and the between-trials adjustments are effective from the beginning to the end of exercise, regardless of the workload output.
