Biobanking facilities are well established in high-income settings,where substantial funding has been invested in infrastructure.In contrast,such facilities are much less developed in resource-restricted settings.Howe...Biobanking facilities are well established in high-income settings,where substantial funding has been invested in infrastructure.In contrast,such facilities are much less developed in resource-restricted settings.However,low-and middle-income countries(LMICs)still face a disproportionately high infectious diseases burden.Thus,the further development of infrastructure facilities,including biobanks is warranted as an important component of this unfolding clinical research environment.This perspective manuscript summarises the challenges and enablers for biobanking in LMICs,with a particular focus on infectious diseases,incorporating some of the lessons learned from the recent coronavirus disease 2019(COVID-19)pandemic.展开更多
1Introduction Synchronous models,a modelling paradigm proposed along with the development of synchronous programming languages[1]in,the 198os,are well-adapted for modelling and specifying reactive systemsa.type of sys...1Introduction Synchronous models,a modelling paradigm proposed along with the development of synchronous programming languages[1]in,the 198os,are well-adapted for modelling and specifying reactive systemsa.type of systems that consecutively interact with their environment at a particular environment-determined rate.In a synchronous model,system behaviours are interpreted as a sequence of reactions.展开更多
文摘Biobanking facilities are well established in high-income settings,where substantial funding has been invested in infrastructure.In contrast,such facilities are much less developed in resource-restricted settings.However,low-and middle-income countries(LMICs)still face a disproportionately high infectious diseases burden.Thus,the further development of infrastructure facilities,including biobanks is warranted as an important component of this unfolding clinical research environment.This perspective manuscript summarises the challenges and enablers for biobanking in LMICs,with a particular focus on infectious diseases,incorporating some of the lessons learned from the recent coronavirus disease 2019(COVID-19)pandemic.
基金supported by the Youth Project of National Natural Science Foundation of China(62102329)the Project of Natural Science Foundation of Chongqing(cste202jeyj-bsho204)the Capacity Development Grant of Southwest University(SWU116007)the Key Projects of National Natural Science Foundation of China(61732019,62032019)。
文摘1Introduction Synchronous models,a modelling paradigm proposed along with the development of synchronous programming languages[1]in,the 198os,are well-adapted for modelling and specifying reactive systemsa.type of systems that consecutively interact with their environment at a particular environment-determined rate.In a synchronous model,system behaviours are interpreted as a sequence of reactions.
