Objective To investigate the prevalence of nonalcoholic fatty liver disease （NAFLD） in different university categories and its association with lifestyle/dietary habits. Methods A cross-sectional study was carried o...Objective To investigate the prevalence of nonalcoholic fatty liver disease （NAFLD） in different university categories and its association with lifestyle/dietary habits. Methods A cross-sectional study was carried out on 9 378 faculty members and staff who participated in an annual health checkup at three universities selected by random cluster sampling. Demographic, anthropometric, biochemical indices and abdominal ultrasound measurements were collected. A nested case-control study was conducted with 200 NAFLD cases and 200 controls matched by gender, age （±3 years）, and university. Results The overall prevalence of NAFLD was 10.3% （13.7% in males and 6.8% in females）. The prevalence was significantly higher in the science and engineering university {22.1%） than in the comprehensive universities with （6.4%） and without （10.9%） medical colleges. Obesity/overweight, hyperlipidemia, diabetes mellitus, and family history of NAFLD were independently associated with higher risk of NAFLD, as were frequent consumption of desserts and salty/spicy foods. Using nutritional supplements was a protective factor against NAFLD. Intake of coarse cereals, potatoes, vegetables, fruits, and milk was significantly lower, and intake of red meat, viscera, candies and pastries, cooking oil, and total energy was significantly higher in participants with NAFLD than in controls. Conclusion Science and engineering university faculty and staff are key targets for NAFLD prevention. NAFLD is closely associated with age, gender, university type, metabolic diseases, and lifestyle/dietary habits.展开更多
基金supported by the Fundamental Research Funds for the Central Universities of the Ministry of Education(2010SCU21002)the Key Technology R&D Program of Sichuan Province(09ZC1270-16)
文摘Objective To investigate the prevalence of nonalcoholic fatty liver disease （NAFLD） in different university categories and its association with lifestyle/dietary habits. Methods A cross-sectional study was carried out on 9 378 faculty members and staff who participated in an annual health checkup at three universities selected by random cluster sampling. Demographic, anthropometric, biochemical indices and abdominal ultrasound measurements were collected. A nested case-control study was conducted with 200 NAFLD cases and 200 controls matched by gender, age （±3 years）, and university. Results The overall prevalence of NAFLD was 10.3% （13.7% in males and 6.8% in females）. The prevalence was significantly higher in the science and engineering university {22.1%） than in the comprehensive universities with （6.4%） and without （10.9%） medical colleges. Obesity/overweight, hyperlipidemia, diabetes mellitus, and family history of NAFLD were independently associated with higher risk of NAFLD, as were frequent consumption of desserts and salty/spicy foods. Using nutritional supplements was a protective factor against NAFLD. Intake of coarse cereals, potatoes, vegetables, fruits, and milk was significantly lower, and intake of red meat, viscera, candies and pastries, cooking oil, and total energy was significantly higher in participants with NAFLD than in controls. Conclusion Science and engineering university faculty and staff are key targets for NAFLD prevention. NAFLD is closely associated with age, gender, university type, metabolic diseases, and lifestyle/dietary habits.
