Characteristics of Multi-Objective Linear Programming Problem and Multi-Objective Linear Fractional Programming Problem Taking Maximum Value of Multi-Objective Functions

In this paper, a new statistical averaging technique is proposed for finding an optimal solution to a multi-objective linear fractional programming problem (MOLFPP) and multi-objective linear programming problem (MOLPP) by using new arithmetic averaging method and new geometric averaging method. It is significantly noticeable same characteristics among all the technique while taking maximum or minimum among all optimized values for multi-objective functions using simplex algorithm. The characteristics provided from the problems are verified by the numerical examples.

Deep-BERT:Transfer Learning for Classifying Multilingual Offensive Texts on Social Media

Offensive messages on social media,have recently been frequently used to harass and criticize people.In recent studies,many promising algorithms have been developed to identify offensive texts.Most algorithms analyze text in a unidirectional manner,where a bidirectional method can maximize performance results and capture semantic and contextual information in sentences.In addition,there are many separate models for identifying offensive texts based on monolin-gual and multilingual,but there are a few models that can detect both monolingual and multilingual-based offensive texts.In this study,a detection system has been developed for both monolingual and multilingual offensive texts by combining deep convolutional neural network and bidirectional encoder representations from transformers(Deep-BERT)to identify offensive posts on social media that are used to harass others.This paper explores a variety of ways to deal with multilin-gualism,including collaborative multilingual and translation-based approaches.Then,the Deep-BERT is tested on the Bengali and English datasets,including the different bidirectional encoder representations from transformers(BERT)pre-trained word-embedding techniques,and found that the proposed Deep-BERT’s efficacy outperformed all existing offensive text classification algorithms reaching an accuracy of 91.83%.The proposed model is a state-of-the-art model that can classify both monolingual-based and multilingual-based offensive texts.

Level of Stress, Predisposing Factors and Status of Mental Health among Pharmacy Students of a Private University of Dhaka, Bangladesh: A Cross Sectional Study

Stress during tertiary educational period has significant negative effect on the performance of a student. Mental distress is increasing among students and is one of the important public health concerns. This study was carried out to investigate the socio demographic characteristics of students, level of their stress feeling, and status of mental health and to find out the co-relation of different factors associated with the level of stress feelings. A cross sectional study was conducted among the students of the Department of Pharmacy of UAP. A total of 504 students (181 male students and 323 female students) participated in this study. Feeling of severe stress was almost equal to both sexes. But, moderate level of stress was more associated with female students (N = 253, F = 78.33%) and overall female students were more stressful than male. Thought towards future career ranked one among many reasons of stress in students (59.67% for male students and 37.46% for female students). In terms of academic achievements, feeling of stress was higher in female students compared to male students (34.98% for female students vs. 15.47% for male students). Other factors such as unrealistic expectations, family relationship and affairs, socio economic condition, being of too busy also significantly participate in the development of stress in young mind. Mental health status was estimated by considering some facts such as state of shock due to unwanted life events, lacking of expression of emotions, reduced feeling of pleasure, unusual thinking, fear of any specific objects, short term memory loss, self identity disorder and lack of self confidence. We co-related different risk factors like age, gender, socio-economic condition, unrealistic thought patter to different levels of stress feeling. Feelings of stress were most among the student of 21 - 25 years of age. Socio-economic condition is always a great factor of stress, middle class society has more stress compared to other socio-economic classes. Psychological counseling is required in educational institution to detect and prevent mental distress and stress among students.

Traditional Use, Phytochemistry, Pharmacological and Toxicological Properties of Acanthus ilicifolius: A Review

The practice of plants for the deterrence and management of innumerable physiological states and diseases dates back to the history of humankind. Although many of today’s medicinal yields are achieved synthetically, they are often modelled on the chemical composition of medicinal plants. In this accordance, Acanthus genus (Family Acanthaceae) has acknowledged considerable attention due to its wide range of secondary metabolites and its customary usage in Indian and Chinese system of medicine. It is worth to mention that A. ilicifolius is enormously medicinal among all the species of Acanthus genus. This plant is considered to be rich sources of steroids, triterpenoids, saponins, flavonoids, alkaloids, and tannins. Traditionally, the plant has been used for asthma, diabetes, dyspepsia, hepatitis, leprosy, neuralgia, paralysis, ringworm, skin disease, snake bite, leukemia. Toxicological investigation in mice model has showed that, the ethanolic extract of the leaves of this plant have no toxic effect up to dose of 1000 mg/kg BW, 2000 mg/kg BW dose have mild toxicity and 5000 mg/kg BW dose have caused toxic effect in some organ system like liver, heart, pancreas, lung and kidney. Different extract of this plant also exhibited Anti-inflammatory, anti-leishmanial, osteoblastic, hepatoprotective, antioxidant and anticancer activities. This review article is an endeavor to cover current expansion in phytochemical and pharmacological potential of this plant species which will be a good reference tool for investigators who wish to work on natural products.

Numerical Simulation of Diffusion Type Traffic Flow Model Using Second-Order Lax-Wendroff Scheme Based on Exponential Velocity Density Function

In order to control traffic congestion, many mathematical models have been used for several decades. In this paper, we study diffusion-type traffic flow model based on exponential velocity density relation, which provides a non-linear second-order parabolic partial differential equation. The analytical solution of the diffusion-type traffic flow model is very complicated to approximate the initial density of the Cauchy problem as a function of x from given data and it may cause a huge error. For the complexity of the analytical solution, the numerical solution is performed by implementing an explicit upwind, explicitly centered, and second-order Lax-Wendroff scheme for the numerical solution. From the comparison of relative error among these three schemes, it is observed that Lax-Wendroff scheme gives less error than the explicit upwind and explicit centered difference scheme. The numerical, analytical analysis and comparative result discussion bring out the fact that the Lax-Wendroff scheme with exponential velocity-density relation of diffusion type traffic flow model is suitable for the congested area and shows a better fit in traffic-congested regions.

Solving Multi-Objective Linear Programming Problem by Statistical Averaging Method with the Help of Fuzzy Programming Method

A multi-objective linear programming problem is made from fuzzy linear programming problem. It is due the fact that it is used fuzzy programming method during the solution. The Multi objective linear programming problem can be converted into the single objective function by various methods as Chandra Sen’s method, weighted sum method, ranking function method, statistical averaging method. In this paper, Chandra Sen’s method and statistical averaging method both are used here for making single objective function from multi-objective function. Two multi-objective programming problems are solved to verify the result. One is numerical example and the other is real life example. Then the problems are solved by ordinary simplex method and fuzzy programming method. It can be seen that fuzzy programming method gives better optimal values than the ordinary simplex method.

Implementation of Efficient B2G and V2G in Practical Cases

In this paper, building to grid(B2G) and vehicle to grid(V2G) have been defined with clear and practical understanding. Both of them are new generation technologies which are the essential part of smart city living and crowd energy clustering. Firstly, an in-detailed overview has been provided with an introduction to B2G and V2G followed by a historical overview and theoretical analysis in respect to smart city planning. Next, a review is conducted on current and previous smart living research, which deals with B2G and V2G. Efficient B2G and V2G implementations in practical cases then have been discussed. Lastly, both of these technical prospects have been analyzed in crowd energy diagram.

Evaluation of Analgesic and Anti-Inflammatory Activities on Ethanolic Extract of <i>Terminalia chebula</i>Fruits in Experimental Animal Models

The present study was undertaken to evaluate the analgesic and anti-inflammatory activities of ethanolic extract of Terminalia chebula (commonly known as Haritaki) fruits in experimental animal models. The study was carried out using Swiss Albino mice (20-25 g) and Long Evans rats (100-150 g) of either sex. The analgesic activity of Terminalia chebula was assessed by using hot plate method. For the determination of analgesic effect, doses of ethanolic extract of Terminalia chebula used in the present study were 250 mg/kg and 500 mg/kg body weight (BW). Anti-inflammatory effect was analyzed by carrageenan induced paw edema method with the administration dose of 300 mg/kg BW of animals. The analysis of experimental data was performed by statistical process of ANOVA to determine the variability of sample, while Dunnet’s test was performed for evaluation of comparative analgesic and anti-inflammatory activity of Terminalia chebula with control and standard. The animals were divided into four treatment groups of six animals each and the “Mean ± SEM” is the statistical identifiable value of the data and P values <0.05 was considered statistically significant. Hot plate test showed a significant increase in the mean reaction time to heat stimuli in hot plate method at both 250 mg/kg and 500 mg/kg BW doses throughout the observation period in 30 minutes and 60 minutes after treatment, which was comparable to the standard ketorolac and control group. In carrageenan induced paw edema method, considerable results were found after determining the percentage change in paw volume in extract. In both cases of analgesic and anti-inflammatory study, % inhibition of pain and inflammation were evaluated. Comparing with control, largest inhibition was found in inhibiting inflammation 5 hours after treatment, while the largest inhibition of pain was obtained in 30 minutes and 60 minutes after treatment of doses. The present study suggests that ethanolic extract of Terminalia chebula fruits has significant analgesic and anti-inflammatory activities.

Fire-Detectors Review and Design of an Automated, Quick Responsive Fire-Alarm System Based on SMS

In this work a review of existing fire-detector types has been carried out along with the development of a low cost, portable, and reliable microcontroller based automated fire alarm system for remotely alerting any fire incidents in household or industrial premises. The aim of the system designed is to alert the distant property-owner efficiently and quickly by sending short message (SMS) via GSM network. A Linear integrated temperature sensor detects temperature beyond preset value whereas semiconductor type sensor detects presence of smoke or gas from fire hazards. The sensor units are connected via common data line to ATMega8L AVR microcontroller. A SIM300CZ GSM kit based network module, capable of operating in standard GSM bands, has been used to send alert messages. The system is implemented on printed circuit board (PCB) and tested under different experimental conditions to evaluate its performances.

Identifying Existing Bus Service Condition and Analyzing Customer Satisfaction of Bus Service in Dhaka City

Bus systems provide a versatile form of public transportation with the flexibility to serve a variety of access needs throughout an urban area. Efficient operation of the public transport is a key factor for the improvement of living condition in Dhaka city. Transport service performance should be assessed from the passengers’ perspectives to evaluate these perceptions in transportation planning. The exploration of service quality of bus is essential in order to provide a better service in future. The objective of this research is to access overall customer satisfaction in public bus transport of Dhaka city. A questionnaire survey was conducted in five locations in Dhaka city. Bus users’ satisfaction was analyzed by discrete choice logit model towards quality, reliability, safety and security and service provided by buses functioning in Dhaka city. The result indicated that more than half of the respondents believed that the present condition of bus service is not satisfactory. In case of the quality of buses, people think that the body and sitting arrangement of the buses are uncomfortable. Regarding the safety and security condition, main three reasons of dissatisfaction of passengers’ are unsafe driving practices, poor boarding and alighting facilities and lack of law enforcing agencies surveillance. Reasons which make the service unsatisfactory include irregular service provided by buses, regular overcrowding, lack of good standard buses and lack of cleanliness. In spite of these negative views, users’ possessed a positive attitude for buses which is the low travel cost.

Investigation of Antidiabetic Effect of Ethanolic Extract of <i>Phyllanthus emblica</i>Linn. Fruits in Experimental Animal Models

Hypoglycemic effects were investigated in the ethanolic extract of fruits of Phyllanthus emblica Linn. with long evans rats (100-120 g). Residual gut sucrose content, gut perfusion and disaccharidase activity studies were carried out to assess these activities. The residual gut sucrose content study was carried out to reveal the amount of sucrose remaining in the gastro intestinal tract (GIT) at six different segments. The ethanolic fruit extract of Phyllanthus emblica Linn. significantly increases the residual sucrose content throughout the gut after sucrose ingestion. Study on intestinal enzyme activity showed that the extract caused a significant (p 0.05), dose dependent inhibition of intestinal disaccharidase enzyme activity. Evaluation of the effect of the plant extract on intestinal enzyme activity showed significant inhibition of intestinal disaccharidase activity, suggesting that reduction of sucrose absorption may be partly related to the inhibition of disaccharidase activity in the gut. The gut perfusion analysis showed that the extract significantly reduced intestinal glucose absorption. The results of the present study suggest that ethanolic extract of Phyllanthus emblica Linn. has significant antidiabetic effects in a dose dependent manner and this may be effective in the treatment of diabetes.

Comparison of the Hypoglycemic, Hypolipidemic and Hepatoprotective Effects of<i>Asparagus racemosus</i>Linn. in Combination with Gliclazide and Pioglitazone on Alloxan-Induced Diabetic Rats

In recent years, the popularity of medicinal plants as a remedy has been increased manifold due to having minimal adverse effects. The current study aimed to compare the hypoglycemic, hypolipidemic and hepatoprotective effects of the ethanolic extract of Asparagus racemosus (EEAR) Linn. alone and combinedly with conventional antidiabetic agents (gliclazide and pioglitazone) in alloxan-induced diabetic rats. Diabetes was induced in male Wister albino rats by the administration of single intra-peritoneal injection of alloxan monohydrate (120 mg/kg b.w.). Effect of oral administration of two different doses of EEAR (200 and 400 mg/kg b.w.), gliclazide (10 mg/kg b.w.) and pioglitazone (10 mg/70kg/b.w.) alone for 2 weeks and a combination of EEAR (200 mg/kg b.w.) with either gliclazide (10 mg/kg b.w.) or pioglitazone (10 mg/70kg/b.w.) for 2 weeks were examined on hypoglycemic activity on 0th, 5th, 10th and 14th day of treatment. After 2 weeks of treatment, hypolipidemic and hepatoprotective effects were estimated by serum biochemical markers such as total cholesterol (TC), triglyceride (TG), low density lipoprotein (LDL), very low density lipoprotein (VLDL), high density lipoprotein (HDL), serum glutamate oxaloacetate transaminases (SGOT), serum glutamate pyruvate trans-aminases (SGPT) and total protein (TP) with the help of commercially available kits. The survival rate, body weight and organ weight were also measured. Alloxan treatment resulted in persistent hyperglycemia, hyperlipidemia and liver dysfunction in rats. Treatment with EEAR at different doses improved hyperglycemia significantly (p th and 14th day of treatment in a dose-dependent mood when compared to the disease control rats, gliclazide treated rats and pioglitazone treated rats. The combination therapy significantly (p th, 10th and 14th day of treatment as compared to that of disease control rats, gliclazide treated rats and pioglitazone treated rats. Proposed adjunct therapy also markedly (p < 0.001;p < 0.01, p < 0.001) improved serum TG, HDL and LDL level with insignificant change in VLDL and TC level while comparing with groups receiving gliclazide treated rats and pioglitazone treated rats. Administration of different doses of EEAR markedly (p < 0.05, p < 0.01, p < 0.001;p < 0.05, p < 0.01;p < 0.05) reduced the activity of TC, TG, LDL, VLDL and HDL cholesterol levels in a dose-dependent approach with respect to that of gliclazide treated rats and pioglitazone treated rats. The effect of combination therapy significantly (p < 0.001;p < 0.001;p < 0.01, p < 0.001) decreased the SGOT, SGPT and TP hepatic enzyme levels when compared to disease control rats, gliclazide treated rats and pioglitazone treated rats indicated improvement in liver dysfunctions. Administration of different doses of EEAR noticeably (p < 0.05, p < 0.01, p < 0.001;p < 0.05, p < 0.01;p < 0.05, p < 0.01) reduced the liver enzymes level including SGOT, SGPT and TP in a dose-dependent manner as compared to the disease control rats, gliclazide treated rats and pioglitazone treated rats. The maximum survival rate (100%) was observed in rats of combination treated rats. No significant changes in the body weight and organ weight to body weight ratio were observed except the groups that were given combined therapy showed improvement in the liver and pancreas weight. Our study suggests that the EEAR potentiates the activity of gliclazide and pioglitazone in controlling blood glucose levels, modifies the lipid profile and improves in liver dysfunction on alloxan-induced diabetic rats.

Energy Harvesting——Technical Analysis of Evolution,Control Strategies,and Future Aspects

This paper provides a technical analysis of energy harvesting (EH) in the field of power and energy sector, including different aspects of harvesting energy, individual case history, control strategies of harvesting in the field of power and energy sector together with the current trend and future aspects of it. EH is comparatively a new concept which is growing very fast since the 20th century and catching new generation research approaches. This paper not only describes the past and current scenarios of harvesting energy with radio frequency (RF) and renewables but also gives author’s own anticipation of the upcoming future trends of it by comparing the case histories.

Technical Analysis of Security Management in Terms of Crowd Energy and Smart Living

In this paper, a technical and statistical analysis of security system and security management is provided for crowd energy and smart living. At the same time, a clear understanding is made for crowd energy concept and next generation smart living. Various case examples have been studied and a brief summary has been provided.Furthermore, a statistical analysis has been provided in terms of security management in smart living where it is found that young technocrats give the highest importance to security management in smart living. Last but not the least, current limitation, constraints, and future scope of security implementation have been discussed in terms of crowd energy clustered with next generation smart living.

Impact of Nicotine Consumption on Hyper Acidic Patients Taking PPI: An <i>In-Vitro</i>and Computational Analysis

The study aims to investigate the protein binding kinetics of nicotine and a PPI (pantoprazole) with Bovine Serum Albumin (BSA) through UV spectroscopy and computational modeling. Data was obtained by using nicotine and pantoprazole and warfarin and diazepam as the two site specific probes on Bovine serum albumin (BSA). In-vitro and in-silico modeling was carried out in creating an environment that simulates the body environment. Cellulose membrane tubes were cut into 9 cm and tied tightly not to let any mixtures leak out. To determine number of binding sites, association constants by using Scatchard plot, predominant binding site of each drug and rise in % of free fraction of one by the other were analyzed using equilibrium dialysis method. Molecular docking further verifies the observations. In Scatchard plot analysis, for nicotine, n1, n2, k1 and k2 = 2.2, 7.6, 0.18 μM&minus;1 and 0.02 μM&minus;1 and for pantoprazole, n1, n2, k1?and k2 = 0.42, 1.2, 0.40 μM&minus;1 and 0.03 μM&minus;1. Nicotine binds more to diazepam site (site-II) and pantoprazole mainly to warfarin site (site-I). In molecular docking, the binding affinity of nicotine being &minus;5.7 kcal/mole demonstrates higher affinity for site-II than that of pantoprazole whose binding affinity is &minus;8.0 kcal/mole. In absence and presence of warfarin, the free fraction of pantoprazole bound to BSA (1:1) was increased from 37.79% to 82.44% and 51.78% to 98.80% respectively by nicotine. On the other hand, free fraction of nicotine was raised by pantoprazole from 12.89% to 75.70% and 50.08% to 99.66% in the absence and presence of diazepam. Both the results of spectroscopic and computational molecular docking suggest that administering pantoprazole with nicotine might increase the % free fraction of pantoprazole more. Thus, nicotine consumption can be beneficial for smoker people taking PPI like pantoprazole.

An Evaluation on Antioxidant Activity, Total Phenolic and Total Flavaonoid Contents of Extracts from <i>Adina cordifolia</i>(Roxb.)

In this study, in vitro antioxidant activity, total phenolic content and concentration of flavonoids of four different extracts of Adina cordifolia (Roxb.) were determined using spectrophotometric methods. Antioxidant activity of extracts was expressed as percentage of DPPH radicals’ inhibition and IC50 values (μg/ml). IC50 values ranged from 20.39 to 38.96 μg/ml. The total phenolic content ranged from 17.48 to 20.83 mg/g of dry weight of extract, expressed as gallic acid equivalents. The total flavonoid concentrations varied from 17.49 to 22.48 mg/g, expressed as quercetin equivalents. The significant linear correlation was confirmed between the values for the total phenolic content and antioxidant activity of plant extracts. Adina cordifolia (Roxb.) can be regarded as promising candidates for natural plant sources of antioxidants with high value.

Profiling of Serum Immunoglobulins in Bangladeshi Major Depressive Disorder Patients

Background: Major Depressive Disorder (MDD) is a mental disorder characterized by a pervasive and persistent low mood which is accompanied by low self-esteem and loss of interest or pleasure in day to day activities that adversely affects a person’s family, work, and personal life. There is no sufficient laboratory test for the diagnosis of MDD and it is expected that this investigation may be helpful for better diagnosis and management of MDD. We aimed to measure serum immunoglobulin levels in MDD patients and control subjects to meet the above demand. Methods: For this purpose, we recruited 88 MDD patients from the department of psychiatry, Bangabandhu Sheikh Mujib Medical University, Dhaka and 89 healthy volunteers from Dhaka city matched with age, sex and socioeconomic status to the patient group. Turbidimetry method was applied to measure serum levels of immunoglobulin A, G, and M where immunoglobulin kit was utilized. Results: The current study revealed that mean serum concentrations of immunoglobulin A, G, and M in patients were found to be 209.07 ± 104.93, 791.50 ± 235.67 and 107.92 ± 47.53 mg/dL while those were 195.34 ± 92.16, 763.81 ± 175.89 and 99.17 ± 48.78 mg/dL in control subjects, respectively. Conclusion: Our result indicates that serum concentrations of immunoglobulin A, G and M were not significant between the groups and further studies are required to establish these findings.

Approach for Grid Connected PV Management:Advance Solar Prediction and Enhancement of Voltage Stability Margin Using FACTS Device

The uncertainty in solar energy is different from conventional,dispatchable generation fuels and difficult to incorporate into the standard system operating procedures.In the first part of this work,the machine learning algorithm is used to train models based on solar irradiance data and different meteorological weather information to predict the solar irradiance for different cities to validate the forecasting model.Again,the intermittent and inertialess nature of photovoltaic(PV)systems can produce significant power oscillations that can cause significant problems with dynamic stability of the power system and also limit the penetration capacity of PV into the grid.In the second part,it is shown that the residue-based power oscillation damping(POD)controller obviously improves the inter-area oscillation damping.The validity and effectiveness of the proposed controller are demonstrated on the three-machine two-area test system that combines the conventional synchronous generator and flexible alternating current transmission systems(FACTS)device using simulations.This report overall puts an in-depth analysis with regard to the challenges of solar resources with integrating,planning,operating,and particularly the stability of the rest of the power grid,including existing generation resources,customer requirements,and the transmission system itself that will lead to an improved decision making in resource allocations and grid stability.

Effects of Velocity and Thermal Slip Conditions with Radiation on Heat Transfer Flow of Ferrofluids

To analyze the thermal convection of ferrofluid along a flat plate is the persistence of this study. The two-dimensional laminar, steady, incompressible flow past a flat plate subject to convective surface boundary condition, slip velocity in the presence of radiation has been studied where the magnetic field is applied in the transverse direction to the plate. Two different kinds of magnetic nanoparticles, magnetite Fe3O4 and cobalt ferrite CoFe2O4 are amalgamated within the base fluids water and kerosene. The effects of various physical aspects such as magnetic field, volume fraction, radiation and slip conditions on the flow and heat transfer characteristics are presented graphically and discussed. The effect of various dimensionless parameters on the skin friction coefficient and heat transfer rate are also tabulated. To investigate this particular problem, numerical computations are done using the implicit finite difference method based Keller-Box Method.