期刊文献+
共找到3篇文章
< 1 >
每页显示 20 50 100
动脉粥样硬化血栓形成门诊患者1年内心血管事件的发生率 被引量:20
1
作者 Gabriel Steg Deepak L. Bhatt +11 位作者 Peter W. F. Wilson Ralph D' Agostino E. Magnus Ohman Joachim Roether Chiau-Suong Liau Alan T. Hirsch Jean-Louis Mas Yasuo Ikeda Michael J. Pencina Shinya Goto 徐成斌(译) 李呈亿(校) 《美国医学会杂志(中文版)》 2007年第4期195-203,共9页
背景:目前,有关社区中动脉粥样硬化血栓形成稳定患者心血管(cardiovascular,CV)事件发生率的资料比较少,既往也无国际性队列研究对冠状动脉病(coronary artery disease,CAD)、脑血管病(cerebrovascular disease,CVD)、外周... 背景:目前,有关社区中动脉粥样硬化血栓形成稳定患者心血管(cardiovascular,CV)事件发生率的资料比较少,既往也无国际性队列研究对冠状动脉病(coronary artery disease,CAD)、脑血管病(cerebrovascular disease,CVD)、外周动脉病(peripheral arterial disease,PAD)确诊患者以及此类疾病高危患者不同事件的发生率进行评估。 目的:在患有动脉疾病的门诊患者或存在多个动脉粥样硬化血栓形成危险因素的门诊患者中确定当今世界1年内CV事件的发生率。 设计、地点及参试者:“减少动脉粥样硬化血栓形成维系健康(Reduction of Artherotllrombosis for Continued Health,REACH)”注册研究是一项国际前瞻性队列研究。研究人员于2003—2004年从44个国家、5587名医生入选68236例已确诊的动脉粥样硬化性血管病患者(CAD、PAD、CVD;n=55814)以及至少存在3个动脉粥样硬化血栓形成危险因素的患者(n=12422)。 主要观测指标:CV死亡、心肌梗死(myocardial infarction,MI)及卒中的发生率。结果:截至2006年7月,共有95.22%的患者(n=64977)提供了1年内的结局。心血管死亡、MI及卒中的总体发生率为4.24%;动脉粥样硬化性血管病患者为4.69%,仅存在多个危险因素的患者为2.15%。CAD、CVD及PAD患者CV死亡、MI及卒中的总体发生率分别为4.52%、6.47%和5.35%。CAD、CVD及PAD患者发生终点事件(即CV死亡、MI、卒中)以及因动脉粥样硬化血栓形成事件入院的几率分别为15.20%、14.53%和21.14%。上述事件发生率随症状性动脉疾病病变部位数量的增加而增加,仅存在危险因素的患者为5.31%,有1处症状性动脉疾病的患者为12.58%,有2处症状性动脉疾病的患者为21.14%,有3处症状性动脉疾病的患者为26.27%(趋势P〈0.001)。 结论:在这项当代大型国际研究中,患有动脉粥样硬化性血管病的门诊患者以及有动脉粥样硬化血栓形成危险的门诊患者CV事件的年发生率相对较高。存在多部位病变者CV事件的1年发生率升高。 展开更多
关键词 动脉粥样硬化血栓形成 心血管事件 年发生率 门诊患者 动脉粥样硬化性血管病 前瞻性队列研究 arterial 动脉疾病
下载PDF
活产、剖宫产和月经异常的发生
2
作者 Abenhaim H.A Harlow B.L 柳蕴 《世界核心医学期刊文摘(妇产科学分册)》 2006年第5期55-56,共2页
To examine the relationship between number of livebirths and cesarean sections on the development of menstrual abnormalities. Methods: The effect of number of livebirths and cesarean sections on menstrual abnormalitie... To examine the relationship between number of livebirths and cesarean sections on the development of menstrual abnormalities. Methods: The effect of number of livebirths and cesarean sections on menstrual abnormalities in the late reproductive period was evaluated using data from the Harvard Study of Moods and Cycles. Results: There were 298 women with no livebirths and 606 women with livebirths of which 184 had a history of cesarean section. Among all women, increasing number of livebirths was associated with an increasing trend in reported heavy menses, prolonged flow > 6 days, and a decreasing trend in reported dysmenorrhea. This effect was amplified among women with a history of cesarean section. Conclusions: Increasing number of livebirths is associated with heavy and prolonged menstrual flow during the late reproductive period. This association is particularly stronger in women with a history of cesarean section. 展开更多
关键词 月经异常 活产 月经过多 经期延长 晚期妇女 周期研究 数据评估
下载PDF
Ambient air pollution and lung disease in China: health effects, study design approaches and future research
3
作者 Jeffrey H. Mandel Christine Wendt +3 位作者 Charles Lo Guangbiao Zhou Marshall Hertz Gurumurthy Ramachandran 《Frontiers of Medicine》 SCIE CAS CSCD 2015年第3期392-400,共9页
Ambient air pollution in China has worsened following dramatic increases in industrialization, automobile use and energy consumption. Particularly bothersome is the increase in the PM2.5 fraction of pollutants. This f... Ambient air pollution in China has worsened following dramatic increases in industrialization, automobile use and energy consumption. Particularly bothersome is the increase in the PM2.5 fraction of pollutants. This fraction has been associated with increasing rates of cardio-respiratory disease in China and elsewhere. Ambient pollutant levels have been described in many of China's cities and are comparable to previous levels in southern California. Lung cancer mortality in China has increased since the 1970s and has been higher in men and in urban areas, the exact explanation for which has not been determined. The estimation of individual risk for Chinese citizens living in areas of air pollution will require further research. Occupational cohort and casecontrol designs each have unique attributes that could make them helpful to use in this setting. Other important future research considerations include detailed exposure assessment and the possible use of biomarkers as a means to better understand and manage the threat posed by air pollution in China. 展开更多
关键词 air pollution PM2.5 lung disease study design EPIDEMIOLOGY
原文传递
上一页 1 下一页 到第
使用帮助 返回顶部