On new classes of strongly Janowski type functions of complex order

We investigate some new subclasses of analytic functions of Janowski type of complex order.We also study inclusion properties,distortion theorems,coefficient bounds and radius of convexity of the functions.Moreover,analytic properties of these classes under certain integral operator are also discussed.Our findings are more comprehensive than the existing results in the literature.

Zinc oxide nanoparticles accelerate the healing of methicillin-resistant Staphylococcus aureus(MRSA)-infected wounds in rabbits

Objective:To synthesize zinc oxide nanoparticles(ZnONPs)and evaluate their antibacterial and wound healing effects against wounds infected with methicillin-resistant Staphylococcus aureus(MRSA).Methods:ZnONPs were prepared by sol-gel method and characterized by X-ray diffraction(XRD)analysis and scanning electron microscopy(SEM).A total of 18 rabbits were divided into three groups:the ZnONPs group,the gentamicin group and the control group.A wound of 3 cm^(2) was inflicted on each rabbit and contaminated with MRSA inoculum.Treatment was started from the fourth day post-surgery.Wound healing,microbiological analysis,and histopathological analysis were performed to assess the efficacy of ZnONPs ointment.Results:XRD analysis confirmed the hexagonal wurtzite structure of the ZnONPs with an average crystallite size of 29.23 nm.SEM revealed discoid-shaped ZnONPs with a rough surface and an average size of 48.36 nm.Energy-dispersive X-ray analysis confirmed the purity of ZnONPs.Moreover,the particle size ranged from 100-700 nm with a high agglomeration trend.Treatment with ZnONPs promoted MRSA-infected wound healing.In addition,ZnONPs showed a good antibacterial effect as evidenced by a dose-dependent increase in the zone of inhibition.Conclusions:ZnONPs accelerate the healing of MRSA-infected wounds.Therefore,it can be explored for the treatment of MRSA infection.

Efficacy and safety of thermobalancing therapy with Dr Allen’s Device for chronic low back pain:A randomised controlled trial

BACKGROUND Lumbar disc herniation and non-specific low back pain are common conditions that seriously affect patients’health-related quality of life(HRQoL).Although empirical evidence has demonstrated that novel Thermobalancing therapy and Dr Allen’s Device can relieve chronic low back pain,there have been no randomised controlled trials for these indications.AIM To evaluate the efficacy of Dr Allen’s Device in lumbar disc herniation(LDH)and non-specific low back pain(NSLBP).METHODS A randomised clinical trial was conducted investigating 55 patients with chronic low back pain due to LDH(n=28)or NSLBP(n=27),out of which 15 were randomly assigned to the control group and 40 were assigned to the treatment group.The intervention was treatment with Dr Allen’s Device for 3 mo.Changes in HRQoL were assessed using the Numerical Pain Rating Scale and the Japanese Orthopedic Association Back Pain Questionnaire.RESULTS Thermobalancing therapy with Dr Allen’s Device showed a significant reduction in pain in the treatment group(P<0.001),with no recorded adverse effects.Both pain assessment scales showed a significant improvement in patients’perception of pain indicating improvement in HRQoL.CONCLUSION The out-of-hospital use of Thermobalancing therapy with Dr Allen’s Device for Low Back Treatment relieves chronic low back pain significantly and without adverse effects,improves the level of activity and HRQoL among patients with LDH and NSLBP.This study demonstrates the importance of this safe first-line therapy that can be used for effective at-home management of chronic low back pain.

Seed Priming and Foliar Supplementation withβ-aminobutyric Acid Alleviates Drought Stress through Mitigation of Oxidative Stress and Enhancement of Antioxidant Defense in Linseed(Linum usitatissimum L.)

Drought is one of the critical limitations to agricultural soils and crop plants.Scarcity of water is increasing due to climate change that lead to increasing threats to global food security.Therefore,ecofriendly and cost effective strategies are highly desirable for mitigating drought stress along with sustainable and smart agricultural production.The aim of the study was to mitigate DS using seed priming and exogenous supplementation ofβ-aminobutyric acid(BABA)in linseed(Linum usitatissimum L.).Different doses(0,50,100 and 150μM)of BABA were used for seed priming agent and foliar spraying under three soil moisture levels viz.,25%(SM25),45%(SM45)and 65%(SM65).The response variables of both experiments included different agro-botanical traits and oxidative stress indicators such as melondialdehyde content,free proline accumulation,and antioxidant defense in plants.The linseed plants showed water stress at SM25 that reduced plant height,number of branches per plant,time taken to flower initiation and heading,and root and shoot dry weights.Additionally,the number of capsules and seeds per capsule showed a significant decline at SM25,which led to a drastic reduction in 100-seed weight yield in linseed plants in both experiments.However,seed priming and foliar supplementation with of BABA(50–100μM)significantly improved these morpho-agronomical attributes in linseed plants under DS.The results revealed that the BABA was fully active in linseed plants at SM25.Interestingly,the combination of SM25 with BABA significantly improved the antioxidant enzymes superoxide dismutase(SOD),catalase(CAT),ascorbate peroxidase(APX),and peroxidase(POD)activity,which significantly enhanced DS tolerance in linseed plants.These findings might be useful to oil seed breeders and farmers linseed for breeding program in linseed plants as well as sustainable agricultural production of oil seed crop plants.

Drought Tolerance in Mung Bean is Associated with the Genotypic Divergence, Regulation of Proline, Photosynthetic Pigment and Water Relation

Drought is one of the critical conditions for the growth and productivity of many crops including mung bean(Vigna radiata L.Wilczek).Screening of genotypes for variations is one of the suitable strategies for evaluating crop adaptability and global food security.In this context,the study investigated the physiological and biochemical responses of four drought tolerant(BARI Mung-8,BMX-08010-2,BMX-010015,BMX-08009-7),and four drought sensitive(BARI Mung-1,BARI Mung-3,BU Mung-4,BMX-05001)mung bean genotypes under wellwatered(WW)and water deficit(WD)conditions.The WW treatment maintained sufficient soil moisture(22%±0.5%,i.e.,30%deficit of available water)by regularly supplying water.Whereas,the WD treatment was maintained throughout the growing period,and water was applied when the wilting symptom appeared.The drought tolerant(DT)genotypes BARI Mung-8,BMX-08010-2,BMX-010015,BMX-08009-7 showed a high level of proline accumulation(2.52–5.99 mg g^(−1) FW),photosynthetic pigment(total chlorophyll 2.96–3.27 mg g^(−1) FW at flowering stage,and 1.62–2.38 mg g^(−1) FW at pod developing stage),plant water relation attributes including relative water content(RWC)(82%–84%),water retention capacity(WRC)(12–14)as well as lower water saturation deficit(WSD)(19%–23%),and water uptake capacity(WUC)(2.58–2.89)under WD condition,which provided consequently higher relative seed yield.These indicate that the tolerant genotypes gained better physiobiochemical attributes and adaptability in response to drought conditions.Furthermore,the genotype BMX-08010-2 showed superiority in terms of those physio-biochemical traits,susceptibility index(SSI)and stress tolerance index(STI)to other genotypes.Based on the physiological and biochemical responses,the BMX-08010-2 was found to be a suitable genotype for sustaining yield under drought stress,and subsequently,it could be recommended for crop improvement through hybridization programs.In addition,the identified traits can be used as markers to identify tolerant genotypes for drought-prone areas.

Effects of medicinal plants on Alzheimer＇s disease and memory deficits

Alzheimer＇s disease is an age-related neurodegenerative disorder characterized by memory deficits. Various studies have been carried out to find therapeutic approaches for Alzheimer＇s disease. However, the proper treatment option is still not available. There is no cure for Alzheimer＇s disease, but symptomatic treatment may improve the memory and other dementia related problems. Traditional medicine is practiced world- wide as memory enhancer since ancient times. Natural therapy including herbs and medicinal plants has been used in the treatment of memory deficits such as dementia, amnesia, as well as Alzheimer＇s disease since a long time. Medicinal plants have been used in different systems of medicine, particularly Unani system of medicines and exhibited their powerful roles in the management and cure of memory disorders. Most of herbs and plants have been chemically evaluated and their efficacy has also been proven in clinical trials. However, the underlying mechanisms of actions are still on the way. In this paper, we have reviewed the role of different medicinal plants that play an important role in the treatment of Alzheimer＇s disease and memory deficits using conventional herbal therapy.

Effects of dietary vitamin E on male reproductive system

Vitamin E is known as important antioxidant to protect the reproductive system. The free radicals are continuously produced in last few years due to metabolic and nutritional deficiencies. These free radicals are responsible for the production of oxidative stress in animal bodies. This production of extensive amount of oxidative stress caused the detrimental effects on the sperm and various other male parameters. This imbalance between the antioxidants and oxidative stress, leads to the condition of infertility in male. Antioxidants play an important role for eliminating of these free radicals. Vitamin E is one of the best antioxidants for the removal of oxidative stress in male reproductive system. Its use increases the reproductive functions and efficiency of male reproductive system. The deficiency of this vitamin leads to degeneration of germinal epithelium and Leydig cells in seminiferous tubules. The use of selenium and vitamin E has the synergistic effects on the male reproductive system. The objective of this review was to collect the beneficial roles of this vitamin along selenium on reproductive system of birds and different animals. This review will also collect the different doses along the beneficial roles on different parameters of male reproductive system.

Agronomy and Economy: Impact of Tillage and Poultry Manure on Mazie (<i>Zea mays</i>L.)

Seedling emergence and seedling establishment are two important phases for the good crop stand and final maize crop harvest. A field study was conducted to explore the effects of different tillage practices and poultry manure levels on the seedling emergence, growth, development, yield, and economics of the spring planted maize during 2010 and 2011. Experimental treatments include four tillage treatments (zero, minimum, conventional and deep tillage) and three poultry manure amendments (control (no manure), 5 Mg·ha-1 and 10 Mg·ha-1). Seedling emergence was linearly affected as the tillage intensity was increased. Significant relationship of tillage with leaf area index, leaf area duration, crop growth rate, net assimilation rate and total dry matter was recorded during the both years. Poultry manure at the rate of 10 Mg·ha-1 produced the higher leaf area index, leaf area duration, crop growth rate, total dry matter and grain yield as compared to 5 Mg·ha-1 and control. Moreover, experimental results concluded that the deep tillage practice has taken less time to start emergence. Similarly, higher values trend of leaf area index, leaf area duration, crop growth rate, total dry matter accumulation and grain yield was shifted from deep tillage to conventional, minimum and zero tillage practices during both years. Economically, the minimum tillage with poultry manure at rate of 10 Mg·ha-1 gave the better benefit to cost ratio and crop productivity as compared to conventional, deep and zero tillage. The experiment suggested the minimum tillage with poultry manure at the rate of 10 Mg·ha-1 may ensure the maize grain yield sustainability.

Phenotypic and Molecular Assessment of Wheat Genotypes Tolerant to Leaf Blight,Rust and Blast Diseases

Globally among biotic stresses,diseases like blight,rust and blast constitute prime constraints for reducing wheat productivity especially in Bangladesh.For sustainable productivity,the development of disease-resistant lines and high yielding varieties is vital and necessary.This study was conducted using 122 advanced breeding lines of wheat including 21 varieties developed by Bangladesh Wheat and Maize Research Institute with aims to identify genotypes having high yield potential and resistant to leaf blight,leaf rust and blast diseases.These genotypes were evaluated for resistance against leaf blight and leaf rust at Dinajpur and wheat blast at Jashore under field condition.Out of 122 genotypes tested,20 lines were selected as resistant to leaf blight based on the area under the diseases progress curve under both irrigated timely sown and irrigated late sown conditions.Forty-two genotypes were found completely free from leaf rust infection,59 genotypes were identified as resistant,and 13 genotypes were identified as moderately resistant to leaf rust.Eighteen genotypes were immune against wheat blast,42 genotypes were categorized as resistant,and 26 genotypes were identified as moderately resistant to wheat blast.Molecular data revealed that the 16 genotypes showed a positive 2NS segment among the 18 immune genotypes selected against wheat blast under field conditions.The genotypes BAW 1322,BAW 1295,and BAW 1203 can be used as earlier maturing genotypes and the genotypes BAW 1372,BAW 1373,BAW 1297 and BAW 1364 can be used for lodging tolerant due to short plant height.The genotypes WMRI Gom 1,BAW 1349 and BAW 1350 can be selected for bold grain and the genotypes WMRI Gom 1,BAW 1297,BAW 1377 can be used as high yielder for optimum seeding condition but genotypes BAW 1377 and BAW 1366 can be used for late sown condition.The selected resistant genotypes against specific diseases can be used in the further breeding program to develop wheat varieties having higher disease resistance and yield potential.

Performance Analysis of ACO-OFDM Visible Light Communication System Based on SCMA

A SCMA ACO-OFDM downlink visible light communication(VLC)system is proposed.Six users share four spectrum resources,four of which are 4 primary color LED lights.ACO-OFDM technology is used to convert the user’s sparse codebook mapped signal into a positive real value signal that can be carried on the light wave,which can realize high-speed parallel communication.Simulation verifies the feasibility of the system.At the same time,the channel model of visible light communication is constructed,and the signal-to-noise ratio(SNR)and channel gain of the visible light channel are systematically analyzed.Finally,the theoretical bit error rate formula using MPA decoding algorithm under different codebook constellation mapping points is given.Through simulation,it is verified that the theoretical bit error rate formula is basically consistent with the simulation bit error rate formula.

One-pot Synthesis,Characterization and Crystal Structure Determination of Novel 1,4,5-Trisubstituted 1,2,3-Triazole with Two Conformational Isomers:1-Benzyl-5-((4-methoxyphenyl)ethynyl)-4-phenyl-1H-1,2,3-triazole

The title compound l-benzyl-5-（（4-methoxyphenyl）ethynyl）-4-phenyl-1H-1,2,3-triazole（C24H19N3O） was designed and synthesized using one-pot strategy and structural characterization was done by single-crystal X-ray diffraction,NMR,IR and MS.This compound was crystallized out from an ethanolic solution in triclinic system,space group P1 with a =9.9038（9）,b = 10.2928（9）,c = 18.8715（19）A°,α = 103.541（6）,β = 90.507（7）,γ = 97.157（7）°,V =1854.2（3） A°3,Z = 4,crystal size（mm） = 0.25 × 0.1 × 0.1 and R（int） = 0.068.Its asymmetric unit contains two independent molecules.The crystal structure of the title compound is stabilized by intramolecular interactions of types C-H…N and C-H…O.Additionally,X-ray analysis reveals obvious C-H…π,π-π stacking interactions between two adjacent aromatic ring planes.

Integrating predictive modeling techniques with geospatial data for landslide susceptibility assessment in northern Pakistan

The eastern road section of the ChinaPakistan Economic Corridor(CPEC)traverses the challenging terrain of northern Pakistan,where frequent landslides pose a significant threat to socioeconomic development and infrastructure.However,the insufficient data on landslide hazards presents a substantial challenge to practical mitigation efforts.Therefore,we conducted an extensive study to gain insight into landslide assessment along the Mansehra-Muzaffarabad-Mirpur and Mangla(MMMM)Expressway.This study involved preparing a landslide inventory,analyzing landslide causative factors,and developing landslide susceptibility models(LSMs)using published data,remote sensing interpretations,field excursions and integrated predictive techniques.We first used Pearson's correlation coefficient(PCC),variable importance factors(VIF),and information gain ratio(IGR)to evaluate multicollinearity among the selected landslide causative factors(LCFs).Then,the topographic roughness index(TRI)with VIF>5 and PCC>0.7 was considered a redundant factor and thus removed before the data modeling.Finally,we adopted multiple machine-learning methods to analyze landslide susceptibility.The results indicate that the landslide inventory contains 1,776 events,of which 674 were classified based on geometrical and lithological configurations.The IGR results show that the rainfall,lithology,PGA,drainage density,slope,and distance to fault are the most effective LCFs.The AUC values for random forest(RF)(0.901),extreme gradient boosting(XGBoost)(0.884),and K-nearest neighbor(KNN)(0.872)remained higher than evidential belief function(EBF)(0.833),weight of evidence(WoE)(0.820),and certainty factor(CF)(0.810),respectively.The RF model outperformed all other models in terms of prediction.However,these models are accurate but newer in the area;thus,susceptible zones were verified with comprehensive field investigations.The northern and central regions accounted for the high and very high susceptibility classes in the final landslide susceptibility mapping(LSM)compared to the southern areas.

Genotypic Divergence, Photosynthetic Efficiency, Sodium Extrusion, and Osmoprotectant Regulation Conferred Salt Tolerance in Sorghum

Salt stress is one of the major limitations to modern agriculture that negatively influences plant growth and productivity.Salt tolerant cultivar can provide excellent solution to enhance stress tolerance with plantfitness to unfavorable environments.Therefore,this study was aimed to screen salt tolerant sorghum genotypes through evaluating of different morphological,biochemical,and physiological attributes in response to salinity stress.In this study,we have been evaluated total six sorghum genotypes including Hybrid sorgo,Debgiri,BD-703,BD-706,BD-707,and BD-725 under salt stress(12 dS m^(-1) NaCl).The response variables included length and weight of root and shoot,root:shoot ratio(RSR),photosynthesis(A),transpiration rate(E),elemental concen-trations(K^(+),Na^(+) and K^(+)/Na^(+)),photochemical efficiency of photosystem II(F_(v)/F_(m)),water use efficiency(WUE)and pigment content(chlorophyll a,and b).The results revealed that saline environment significantly reduced all response variables under study of sorghum genotypes,however,Hybrid sorgo remained unmatched by recording the maximum root and shoot traits.The same genotype recorded higher photosynthetic efficiency which was attributed to Na^(+) extrusion,K^(+) uptake and higher K^(+)/Na^(+) ratio(1.8 at stress),while these mechanisms were not fully active in rest of genotypes.Moreover,this study also implies the involvement of proline in imparting tolerance against saline environment in Hybrid sorgo genotype.Overall,BD-703 remained the most salt sensitive genotype as evident from the minimum morphological growth traits and the least biosynthesis of osmoprotectants.Thesefindings open new research avenues for salt stress alleviation by identifying elite salt-to-lerant genotypes of sorghum for breeding programs.

Recent Developments to Mitigate Selenium Deficiency in Agricultural Eco-Systems

Under changing climate,trace elements like selenium(Se)have emerged as vital constituent of agro-ecosystems enabling crop plants to off-set the adverse effects of suboptimal growth conditions.The available form of selenium is important for boosting its bioavailability to crop plants having varied agro-botanical traits and root architectural systems.As compared to selenite,the selenate has a weaker soil bonding,higher absorption in the soil solution which results in a comparatively absorption by plant roots.Various factors including dry climate,high pH,optimal ambient air temperature,less accumulation of water,and low concentration of organic matter in the soil tend to boost the selenate ratio in the soil.The use of selenium pelleted seeds has emerged as an interesting and viable alternative to alleviate selenium deficiency in agricultural eco-systems.Similarly,the co-inoculation of a mixture of Selenobacteria and Arbuscular mycorrhizal fungi represents an evolving promising strategy for the bio-fortification of wheat plants to produce selenium-rich flour to supplement human dietary needs.Furthermore,in-depth research is required to assure the effectiveness of biological fertilization procedures in field conditions as well as to explore and increase our understanding pertaining to the underlying main mechanisms and channels of selenium absorption in plants.The focus of this review is to synthesize the recent developments on Se dynamics in soil-plant systems and emerging promising strategies to optimize its levels for crop plants.Recent developments regarding the use of micro-organisms as a biotechnological mean to enhance plant nutrition and crop quality have been objectively elaborated.The study becomes even more pertinent for arid and semi-arid agro-ecosystems owing to the potential role of selenium in providing stress tolerance to crop plants.Moreover,this review synthesizes and summarizes the recent developments on climate change and bioavailability,and the protective role of selenium in crop plants.

Mathematical analysis of Hepatitis C Virus infection model in the framework of non-local and non-singular kernel fractionalderivative

In this paper,we study a mathematical model of Hepatitis C Virus(HCV)infection.We present a compartmental mathematical model involving healthy hepatocytes,infected hepatocytes,non-activated dendritic cells,activated dendritic cells and cytotoxic T lymphocytes.The derivative used is of non-local fractional order and with non-singular kernel.The existence and uniqueness of the system is proven and its stability is analyzed.Then,by applying the Laplace Adomian decomposition method for the fractional derivative,we present the semi-analytical solution of the model.Finally,some numerical simulations are performed for concrete values of the parameters and several graphs are plotted to reveal the qualitative properties of the solutions.

Effect of Plant Growth-Promoting Rhizobacteria on Growth,Nodulation and Nutrient Accumulation of Lentil Under Controlled Conditions

Application of plant growth-promoting rhizobacteria (PGPR) has been shown to increase legume growth and development under field and controlled environmental conditions. The present study was conducted to isolate plant growth-promoting rhizobacteria (PGPR) from the root nodules of lentil (Lens culinaris Medik.) grown in arid/semi-arid region of Punjab, Pakistan and examined their plant growth-promoting abilities. Five bacterial isolates were isolated, screened in vitro for plant growth-promoting (PGP) characteristics and their effects on the growth of lentil were assessed under in vitro, hydroponic and greenhouse (pot experiment) conditions. All the isolates were Gram negative, rod-shaped and circular in form and exhibited the plant growth-promoting attributes of phosphate solubilization and auxin (indole acetic acid, IAA) production. The IAA production capacity ranged in 0.5-11.0 μg mL-1 and P solubilization ranged in 3-16 mg L-1 . When tested for their effects on plant growth, the isolated strains had a stimulatory effect on growth, nodulation and nitrogen (N) and phosphorus (P) uptake in plants on nutrient-deficient soil. In the greenhouse pot experiment, application of PGPR significantly increased shoot length, fresh weight and dry weight by 65%, 43% and 63% and the increases in root length, fresh weight and dry weight were 74%, 54% and 92%, respectively, as compared with the uninoculated control. The relative increases in growth characteristics under in vitro and hydroponic conditions were even higher. PGPR also increased the number of pods per plant, 1 000-grain weight, dry matter yield and grain yield by 50%, 13%, 28% and 29%, respectively, over the control. The number of nodules and nodule dry mass increased by 170% and 136%, respectively. After inoculation with effective bacterial strains, the shoot, root and seed N and P contents increased, thereby increasing both N and P uptake in plants. The root elongation showed a positive correlation (R2 = 0.67) with the IAA production and seed yield exhibited a positive correlation (R2 = 0.82) with root nodulation. These indicated that the isolated PGPR rhizobial strains can be best utilized as potential agents or biofertilizers for stimulating the growth and nutrient accumulation of lentil.

Qualitative properties and bifurcations of discrete-time Bazykin–Berezovskaya predator–prey model

The positive connection between the total individual fitness and population density is called the demographic Allee effect.A demographic Allee effect with a critical population size or density is strong Allee effect.In this paper,discrete counterpart of Bazykin–Berezovskaya predator–prey model is introduced with strong Allee effects.The steady states of the model,the existence and local stability are examined.Moreover,proposed discrete-time Bazykin–Berezovskaya predator–prey is obtained via implementation of piecewise constant method for differential equations.This model is compared with its continuous counterpart by applying higher-order implicit Runge–Kutta method(IRK)with very small step size.The comparison yields that discrete-time model has sensitive dependence on initial conditions.By implementing center manifold theorem and bifurcation theory,we derive the conditions under which the discrete-time model exhibits flip and Niemark–Sacker bifurcations.Moreover,numerical simulations are provided to validate the theoretical results.

Omicron variants breakthrough infection elicited higher specific memory immunity than third dose booster in healthy vaccinees

Homologous booster,heterologous booster,and Omicron variants breakthrough infection(OBI)could improve the humoral immunity against Omicron variants.Questions concerning about memory B cells(MBCs)and T cells immunity against Omicron variants,features of long-term immunity,after booster and OBI,needs to be explored.Here,comparative analysis demonstrate antibody and T cell immunity against ancestral strain,Delta and Omicron variants in Omicron breakthrough infected patients(OBIPs)are comparable to that in Ad5-nCoV boosted healthy volunteers(HVs),higher than that in inactivated vaccine(InV)boosted HVs.However,memory B cells(MBCs)immunity against Omicron variants was highest in OBIPs,followed by Ad5-nCoV boosted and InV boosted HVs.OBIPs and Ad5-nCoV boosted HVs have higher classical MBCs and activated MBCs,and lower naïve MBCs and atypical MBCs relative to both vaccine boosted HVs.Collectively,these data indicate Omicron breakthrough infection elicit higher MBCs and T cells against SARS-CoV-2 especially Omicron variants relative to homologous InV booster and heterologous Ad5-nCoV booster.

Relationship between gut microbiota and host-metabolism:Emphasis on hormones related to reproductive function

It has been well recognized that interactions between the gut microbiota and host-metabolism have a proven effect on health.The gut lumen is known for harboring different bacterial communities.Microbial by-products and structural components,which are derived through the gut microbiota,generate a signaling response to maintain homeostasis.Gut microbiota is not only involved in metabolic disorders,but also participates in the regulation of reproductive hormonal function.Bacterial phyla,which are localized in the gut,allow for the metabolization of steroid hormones through the stimulation of different enzymes.Reproductive hormones such as progesterone,estrogen and testosterone play a pivotal role in the successful completion of reproductive events.Disruption in this mechanism may lead to reproductive disorders.Environmental bacteria can affect the metabolism,and degrade steroid hor-mones and their relevant compounds.This behavior of the bacteria can safely be implemented to eliminate steroidal compounds from a polluted environment.In this review,we summarize the meta-bolism of steroid hormones on the regulation of gut microbiota and vice-versa,and also examined the significant influence this process has on various events of reproductive function.Altogether,the evidence suggests that steroid hormones and gut microbiota exert a central role in the modification of host bacterial action and impact the reproductive efficiency of animals and humans.