This preliminary study shows an innovative concept of searching for peat substitutes on basis of renewable raw materials considering the cultivation in extensive land use in Lower Saxony (Germany). Selecting suitable ...This preliminary study shows an innovative concept of searching for peat substitutes on basis of renewable raw materials considering the cultivation in extensive land use in Lower Saxony (Germany). Selecting suitable raw material plants against the background of ecological, social and economic issues followed by testing series including those materials should lead on to reliable results for a planned transition through a spatial analysis of potential areas for cultivation with a specific attention on wetlands. Thereby this short report illustrates the concept of the study as well as chosen interim results and it is to be understood as the first paper of a mini-series.展开更多
Background Public interest in the way food is produced on the farm and processed along the food-production chain is increasing.The analysis of isotopic signatures(^(13)C)in cow tail hair provides a method to reconstru...Background Public interest in the way food is produced on the farm and processed along the food-production chain is increasing.The analysis of isotopic signatures(^(13)C)in cow tail hair provides a method to reconstruct the dietary proportion of maize in cow diets.Based on this,we further investigated whether there is a relationship between isotopic signatures in cow tail hair or farm slurry and the proportion of maize of the total utilized agricultural area per farm[%].We did an on-farm survey on 17 dairy farms in coastal Northwest Germany and collected cow tail hair from dairy cows and slurry samples on each farm.The farms differed in their feeding regime(C_(3) vs.C_(4) plants),their site conditions(sandy soil=‘Geestland’;organic soil=‘Peatland’;clayey soil=‘Marshland’),and in the area cultivated with maize as a proportion of the total utilized agricultural area per farm.Results We found a positive relationship between δ^(13)C values in both cow tail hair and slurry and the annual dietary proportion of maize(R^(2)=0.67;and R^(2)=0.63).Furthermore,we confirmed that there was a relationship betweenδ^(13)C values in cow tail hair and area of maize as a proportion of the total utilized agricultural area per farm(R^(2)=0.69).Conclusion Our findings suggest a general applicability of using isotopic signatures(^(13)C)along a wide gradient of site conditions and productions systems in practice.展开更多
Computerized cognitive training (CCT) can improve cognition in older adults. However, specific programs for this target group have rarely been developed, and predictors of training success are largely unclear. In a ra...Computerized cognitive training (CCT) can improve cognition in older adults. However, specific programs for this target group have rarely been developed, and predictors of training success are largely unclear. In a randomized controlled pilot trial, we examined effects of a six-week CCT, tailored to the cognitive profile of healthy older adults (EG, n = 21) as compared to a nonspecific CCT (CG, n = 18) matched in frequency and intensity. No interaction effects between Group and Time were found. However, within-group analysis showed significant gains in verbal and non-verbal memory, executive and visuospatial functions and subjective cognitive concerns (SCC) in the EG, while the CG only benefitted in non-verbal memory and set-shifting. Low cognitive performance and lower SCC at baseline were the most consistent predictors of cognitive gains in the EG. Thus, CCTs specifically tailored to older adults seem advantageous compared to non-specific CCT. Further, we conclude that SCC may be related to reduced cognitive plasticity.展开更多
Background:Selective grazing creates stable patches of contrasting sward height,thereby providing different growth conditions for the grass sward above and below ground and potentially affecting soil organic carbon(SO...Background:Selective grazing creates stable patches of contrasting sward height,thereby providing different growth conditions for the grass sward above and below ground and potentially affecting soil organic carbon(SOC)stocks.We hypothesized that the presence of patches leads to greater spatial variability in belowground biomass(BGB)and SOC stocks than occurs between pastures managed under different stocking intensities.Methods:A long-term grazing experiment consisting of three stocking intensities was used for this study.We studied BGB,SOC,and soil total nitrogen(Ntot)stocks in the 0-15 cm soil depth.Shannon diversity of plant species,soil bulk density,soil phosphorus,potassium,and magnesium contents were considered.Results:There were no significant effects of patch or stocking intensity on BGB,SOC,and Ntot stocks.Short patches had a greater Shannon diversity than tall patches(p<0.05)and plant-available nutrients in soil correlated positively with sward height(p<0.05).Conclusions:We conclude from the current results and previous studies that higher plant species diversity with lower soil nutrient contents in short-patch areas and higher nutrient contents together with light competition in tall-patch areas might balance each other out with respect to BGB and SOC stocks.展开更多
Background:IgG-class autoantibodies to N-Methyl-D-Aspartate(NMDA)-type glutamate receptors define a novel entity of autoimmune encephalitis.Studies examining the prevalence of NMDA IgA/IgM antibodies in patients with ...Background:IgG-class autoantibodies to N-Methyl-D-Aspartate(NMDA)-type glutamate receptors define a novel entity of autoimmune encephalitis.Studies examining the prevalence of NMDA IgA/IgM antibodies in patients with Parkinson disease with/without dementia produced conflicting results.We measured NMDA antibodies in a large,well phenotyped sample of Parkinson patients without and with cognitive impairment(n=296)and controls(n=295)free of neuropsychiatric disease.Detailed phenotyping and large numbers allowed statistically meaningful correlation of antibody status with diagnostic subgroups as well as quantitative indicators of disease severity and cognitive impairment.Methods:NMDA antibodies were analysed in the serum of patients and controls using well established validated assays.We used anti-NMDA antibody positivity as the main independent variable and correlated it with disease status and phenotypic characteristics.Results:The frequency of NMDA IgA/IgM antibodies was lower in Parkinson patients(13%)than in controls(22%)and higher than in previous studies in both groups.NMDA IgA/IgM antibodies were neither significantly associated with diagnostic subclasses of Parkinson disease according to cognitive impairment,nor with quantitative indicators of disease severity and cognitive impairment.A positive NMDA antibody status was positively correlated with age in controls but not in Parkinson patients.Conclusion:It is unlikely albeit not impossible that NMDA antibodies play a significant role in the pathogenesis or progression of Parkinson disease e.g.to Parkinson disease with dementia,while NMDA IgG antibodies define a separate disease of its own.展开更多
基金facilitated by the Ministry of Food,Agriculture and Consumer Protection of Lower Saxony(Germany).
文摘This preliminary study shows an innovative concept of searching for peat substitutes on basis of renewable raw materials considering the cultivation in extensive land use in Lower Saxony (Germany). Selecting suitable raw material plants against the background of ecological, social and economic issues followed by testing series including those materials should lead on to reliable results for a planned transition through a spatial analysis of potential areas for cultivation with a specific attention on wetlands. Thereby this short report illustrates the concept of the study as well as chosen interim results and it is to be understood as the first paper of a mini-series.
基金supported by the Federal Office for Agriculture and Food(BLE)within the collaborative research project‘Waterbuddies’,support code:2817NA004We acknowledge funding by the Open Access Publication Funds of the Göttingen UniversityOpen Access funding enabled and organized by Projekt DEAL.
文摘Background Public interest in the way food is produced on the farm and processed along the food-production chain is increasing.The analysis of isotopic signatures(^(13)C)in cow tail hair provides a method to reconstruct the dietary proportion of maize in cow diets.Based on this,we further investigated whether there is a relationship between isotopic signatures in cow tail hair or farm slurry and the proportion of maize of the total utilized agricultural area per farm[%].We did an on-farm survey on 17 dairy farms in coastal Northwest Germany and collected cow tail hair from dairy cows and slurry samples on each farm.The farms differed in their feeding regime(C_(3) vs.C_(4) plants),their site conditions(sandy soil=‘Geestland’;organic soil=‘Peatland’;clayey soil=‘Marshland’),and in the area cultivated with maize as a proportion of the total utilized agricultural area per farm.Results We found a positive relationship between δ^(13)C values in both cow tail hair and slurry and the annual dietary proportion of maize(R^(2)=0.67;and R^(2)=0.63).Furthermore,we confirmed that there was a relationship betweenδ^(13)C values in cow tail hair and area of maize as a proportion of the total utilized agricultural area per farm(R^(2)=0.69).Conclusion Our findings suggest a general applicability of using isotopic signatures(^(13)C)along a wide gradient of site conditions and productions systems in practice.
基金supported by the Federal Ministry of Education and Research under Grant 16SV5917.
文摘Computerized cognitive training (CCT) can improve cognition in older adults. However, specific programs for this target group have rarely been developed, and predictors of training success are largely unclear. In a randomized controlled pilot trial, we examined effects of a six-week CCT, tailored to the cognitive profile of healthy older adults (EG, n = 21) as compared to a nonspecific CCT (CG, n = 18) matched in frequency and intensity. No interaction effects between Group and Time were found. However, within-group analysis showed significant gains in verbal and non-verbal memory, executive and visuospatial functions and subjective cognitive concerns (SCC) in the EG, while the CG only benefitted in non-verbal memory and set-shifting. Low cognitive performance and lower SCC at baseline were the most consistent predictors of cognitive gains in the EG. Thus, CCTs specifically tailored to older adults seem advantageous compared to non-specific CCT. Further, we conclude that SCC may be related to reduced cognitive plasticity.
基金funded by the German Ministry of Education and Research(BMBF)under grant number(031B0510A)a part of the research project SIGNAL(Sustainable intensification of agriculture through agroforestry)within the Framework Program BONARES(Soil as a sustainable resource for the bioeconomy).
基金ERASMUS+program and 774124-SUPER G(EU Horizon 2020)。
文摘Background:Selective grazing creates stable patches of contrasting sward height,thereby providing different growth conditions for the grass sward above and below ground and potentially affecting soil organic carbon(SOC)stocks.We hypothesized that the presence of patches leads to greater spatial variability in belowground biomass(BGB)and SOC stocks than occurs between pastures managed under different stocking intensities.Methods:A long-term grazing experiment consisting of three stocking intensities was used for this study.We studied BGB,SOC,and soil total nitrogen(Ntot)stocks in the 0-15 cm soil depth.Shannon diversity of plant species,soil bulk density,soil phosphorus,potassium,and magnesium contents were considered.Results:There were no significant effects of patch or stocking intensity on BGB,SOC,and Ntot stocks.Short patches had a greater Shannon diversity than tall patches(p<0.05)and plant-available nutrients in soil correlated positively with sward height(p<0.05).Conclusions:We conclude from the current results and previous studies that higher plant species diversity with lower soil nutrient contents in short-patch areas and higher nutrient contents together with light competition in tall-patch areas might balance each other out with respect to BGB and SOC stocks.
基金Intramural funding of the Dept.of Neurology,Kiel University.
文摘Background:IgG-class autoantibodies to N-Methyl-D-Aspartate(NMDA)-type glutamate receptors define a novel entity of autoimmune encephalitis.Studies examining the prevalence of NMDA IgA/IgM antibodies in patients with Parkinson disease with/without dementia produced conflicting results.We measured NMDA antibodies in a large,well phenotyped sample of Parkinson patients without and with cognitive impairment(n=296)and controls(n=295)free of neuropsychiatric disease.Detailed phenotyping and large numbers allowed statistically meaningful correlation of antibody status with diagnostic subgroups as well as quantitative indicators of disease severity and cognitive impairment.Methods:NMDA antibodies were analysed in the serum of patients and controls using well established validated assays.We used anti-NMDA antibody positivity as the main independent variable and correlated it with disease status and phenotypic characteristics.Results:The frequency of NMDA IgA/IgM antibodies was lower in Parkinson patients(13%)than in controls(22%)and higher than in previous studies in both groups.NMDA IgA/IgM antibodies were neither significantly associated with diagnostic subclasses of Parkinson disease according to cognitive impairment,nor with quantitative indicators of disease severity and cognitive impairment.A positive NMDA antibody status was positively correlated with age in controls but not in Parkinson patients.Conclusion:It is unlikely albeit not impossible that NMDA antibodies play a significant role in the pathogenesis or progression of Parkinson disease e.g.to Parkinson disease with dementia,while NMDA IgG antibodies define a separate disease of its own.