The mineralogical and geochemical characteristics of sediments of Core CSH1, which was collected from the northern Okinawa Trough, indicate that large amounts of volcanic materials have deposited in the northern Okina...The mineralogical and geochemical characteristics of sediments of Core CSH1, which was collected from the northern Okinawa Trough, indicate that large amounts of volcanic materials have deposited in the northern Okinawa Trough during the Holocene. On the basis of down-core variations in mineral and element contents of sediments, two layers in the uppermost section of Core CSH 1 characterized by high quartz, Na2O, MnO, K20, uranium contents and low contents of clay minerals, volatiles, Fe2O3, MgO, CaO and strontium, have been identified as the tephra deposits. Systematic grain-size measurements also suggest that sediments from the northern Okinawa Trough are made up of terrigenous materials and volcanic ashes with different proportion during the Holocene. The sedi- ments of tephra layers in Core CSH1 show bi-modal patterns in grain-size distribution with modal grain-sizes of 74.3 and 7.81 μm, respectively. According to the radiocarbon dating on shells of zooplankton foraminifera, two tephra layers in Core CSH1, formed at 7 250 and 10 870 a BP (cal), approximately correspond to the K-Ah tephra [7 300 a BP (cal)] and the eruption of Kuju Volcano (12-10 ka BP), respectively.展开更多
With the increasing pressure on companies to engage in corporate social responsibility (CSR), it is paramount for businesses and organizations to gain social legitimacy through building trust and credibility towards...With the increasing pressure on companies to engage in corporate social responsibility (CSR), it is paramount for businesses and organizations to gain social legitimacy through building trust and credibility towards their stakeholders. Corporate reporting is a major tool whereby they can demonstrate their transparency and their will to contribute to society. However, reporting is often addressed as a narrow and restricted discipline based on specific areas of communication like financial and CSR communication, which potentially can lead to "disconnected reporting". The aim of this paper is to address reporting within a framework of corporate communication, introducing the concept of corporate reporting as "an issue of integration" and to discuss the opportunities and challenges of corporate reporting as a driver for gaining social legitimacy. Recent research in corporate reporting and the development of standards by distinguished reporting agencies (e.g., Klynveld Peat Marwick Goerdeler (KPMG), A4S, PricewaterhouseCoopers (PwC)) seem to support this position, arguing that integrated reporting is "the way forward". Accordingly, the authors conclude that there is a need to include a broader range of aspects in the corporate reporting literature applying a strategic integrated approach by which corporate reporting may more explicitly help businesses and organizations gain social legitimacy towards their internal and external stakeholders.展开更多
Array comparative genomic hybridization (CGH) has been popularly used for analyzing DNA copy number variations in diseases like cancer. In this study, we investigated 82 sporadic samples from 49 breast cancer patien...Array comparative genomic hybridization (CGH) has been popularly used for analyzing DNA copy number variations in diseases like cancer. In this study, we investigated 82 sporadic samples from 49 breast cancer patients using 1-Mb resolution bacterial artificial chromosome (2GH arrays. A number of highly frequent genomic aberrations were discovered, which may act as "drivers" of tumor progression. Meanwhile, the genomic profiles of four "normal" breast tissue samples taken at least 2 cm away from the primary tumor sites were also found to have some genomic aberrations that recurred with high frequency in the primary tumors, which may have important implications for clinical therapy. Additionally, we performed class comparison and class prediction for various clinicopathological parameters, and a list of characteristic genomic aberrations associated with different clinicopathological phenotypes was compiled. Our study provides clues for further investigations of the underlying mechanisms of breast carcinogenesis.展开更多
基金supported by the International Cooperation Project"High-Resolution Sequence of Quaternary:Paleoenvironmental and Paleoclimatic Evolution in the East China Sea"under contract No.2002DFG00034the Youth Science Foundation Project of S0A under contract No.2003305the Key Program of National Natural Science Foundation of China under contract No.40431002.
文摘The mineralogical and geochemical characteristics of sediments of Core CSH1, which was collected from the northern Okinawa Trough, indicate that large amounts of volcanic materials have deposited in the northern Okinawa Trough during the Holocene. On the basis of down-core variations in mineral and element contents of sediments, two layers in the uppermost section of Core CSH 1 characterized by high quartz, Na2O, MnO, K20, uranium contents and low contents of clay minerals, volatiles, Fe2O3, MgO, CaO and strontium, have been identified as the tephra deposits. Systematic grain-size measurements also suggest that sediments from the northern Okinawa Trough are made up of terrigenous materials and volcanic ashes with different proportion during the Holocene. The sedi- ments of tephra layers in Core CSH1 show bi-modal patterns in grain-size distribution with modal grain-sizes of 74.3 and 7.81 μm, respectively. According to the radiocarbon dating on shells of zooplankton foraminifera, two tephra layers in Core CSH1, formed at 7 250 and 10 870 a BP (cal), approximately correspond to the K-Ah tephra [7 300 a BP (cal)] and the eruption of Kuju Volcano (12-10 ka BP), respectively.
文摘With the increasing pressure on companies to engage in corporate social responsibility (CSR), it is paramount for businesses and organizations to gain social legitimacy through building trust and credibility towards their stakeholders. Corporate reporting is a major tool whereby they can demonstrate their transparency and their will to contribute to society. However, reporting is often addressed as a narrow and restricted discipline based on specific areas of communication like financial and CSR communication, which potentially can lead to "disconnected reporting". The aim of this paper is to address reporting within a framework of corporate communication, introducing the concept of corporate reporting as "an issue of integration" and to discuss the opportunities and challenges of corporate reporting as a driver for gaining social legitimacy. Recent research in corporate reporting and the development of standards by distinguished reporting agencies (e.g., Klynveld Peat Marwick Goerdeler (KPMG), A4S, PricewaterhouseCoopers (PwC)) seem to support this position, arguing that integrated reporting is "the way forward". Accordingly, the authors conclude that there is a need to include a broader range of aspects in the corporate reporting literature applying a strategic integrated approach by which corporate reporting may more explicitly help businesses and organizations gain social legitimacy towards their internal and external stakeholders.
基金supported by the Danish Cancer Soci-ety through the budget of the Institute of Cancer Biol-ogy and by grants from the Danish Medical Research Council, the Natural and Medical Sciences Committee of the Danish Cancer Society, Novo Nordisk, the John and Birthe Meyer Foundation, the Solar Fonden, the Stensbygaard Fonden, the Kai Langeog Gundhild Kai Lange Fond, the will of Edith Stern, and the "Race Against Breast Cancer" ProjectThe support of the Marketing Department at the Danish Cancer Society is greatly appreciatedsupported by a project grant from the Hi-Tech Research and Development Program of China (2006AA02A301)
文摘Array comparative genomic hybridization (CGH) has been popularly used for analyzing DNA copy number variations in diseases like cancer. In this study, we investigated 82 sporadic samples from 49 breast cancer patients using 1-Mb resolution bacterial artificial chromosome (2GH arrays. A number of highly frequent genomic aberrations were discovered, which may act as "drivers" of tumor progression. Meanwhile, the genomic profiles of four "normal" breast tissue samples taken at least 2 cm away from the primary tumor sites were also found to have some genomic aberrations that recurred with high frequency in the primary tumors, which may have important implications for clinical therapy. Additionally, we performed class comparison and class prediction for various clinicopathological parameters, and a list of characteristic genomic aberrations associated with different clinicopathological phenotypes was compiled. Our study provides clues for further investigations of the underlying mechanisms of breast carcinogenesis.