Malaria control programme utilizing indoor residual spraying of chemical insecticide is only effective if a high coverage of targeted area is achieved. The effectiveness of the residual spraying, on the other hand, re...Malaria control programme utilizing indoor residual spraying of chemical insecticide is only effective if a high coverage of targeted area is achieved. The effectiveness of the residual spraying, on the other hand, relies on the efficacy and residual activity of the insecticides applied, which to a certain extent are influenced by the nature of the sprayed surfaces. The bioefficacy of indoor residual-sprayed deltamethrin wettable granule (WG) formulation for the control of malaria was compared with the current dose of deltamethrin wettable powder (WP) in malaria endemic areas in Balai Ringin, Sarawak. Doses of 20 mg/m2 WP (control), 20 mg/m2 WG, 30 mg/m2 WG and 40 mg/m2 WG were sprayed separately on different surfaces namely, wooden, rough-bamboo, smooth-bamboo and brick surfaces. Residual activity of WP and WG formulations was tested against lab-bred Anopheles maculatus using WHO standard procedure. Deltamethrin at 30 mg/m2 WG exhibited the highest sustainable level of effectiveness against An. maculatus (An. maculatus mortality was between 95% - 100%) up to week 60 post-spraying when sprayed on smooth- bamboo surface. These results indicated that 30 mg/m2 WG could be an ideal concentration for controlling malaria vector effectively up to 15 months of which long-lasting residual spraying was envisaged. The usual two spraying cycles per year with 20 mg/m2 deltamethrin WP could be replaced with 30 mg/m2 deltamethrin WG since the long residual activity was achieved by employing a single spraying only.展开更多
Early diagnosis and complete treatment are the most important components of the malaria control program, which have a direct bearing on prevention of mortality and reduction in the morbidity, therefore, follow-up of t...Early diagnosis and complete treatment are the most important components of the malaria control program, which have a direct bearing on prevention of mortality and reduction in the morbidity, therefore, follow-up of the patient treatment is an important aspect of monitoring disease in the community. Aims: To assess treatment compliance among confirmed malaria cases in Gandhinagar District and to determine the proportion of cure rate with complete treatment as per the national drug policy. Study Variables: Exploratory-rural and urban areas;outcome-compliance, cure rate. Analysis: Percentage, proportions. Results: Compliance among 192 subjects under the study conducted in 2008 i.e. confirmed that malaria cases were 88% even after the introduction of 14 day therapy for “Plasmodium vivax” cases, while 100% cure rate was observed on the follow-up till the 28th day among “P. vivax” and “P. falciparum” cases which helped in reducing malaria incidence in the rural area by 50% as compared to the preceding year of the study. Conclusion: Follow-up of the treatment given to malaria patients has enhanced compliance and cure rate, which in turn contributed towards interruption of transmission. Therefore, a better cure rate through the administration of effective antimalarial drugs as per the drug policy in combination with other containment measures is the right strategy to keep morbidity and mortality due to malaria under effective control.展开更多
Background: Government of India has lunched the frame work for eliminating malaria from the country by 2030 [1] [2]. But progressive States like Gujarat has to achieve the target by 2024. The first step in this direct...Background: Government of India has lunched the frame work for eliminating malaria from the country by 2030 [1] [2]. But progressive States like Gujarat has to achieve the target by 2024. The first step in this direction is to bring down the Annual Parasitic Incidence less than 1.0. Under National Vector Borne Disease Control Programme (NVBDCP) various activities for Vector control coupled with complete treatment to confirm malaria cases within 24 hours were given more focus and implemented diligently and effectively. Aim: To evaluate the progress of the efforts being undertaken for malaria elimination in Gandhinagar district. Design: Impact of malaria control efforts in Gandhinagar district covering all areas were studied in detail. Setting: Malaria prone villages of Gandhinagar district where preventive actions were undertaken in an integrated manner during the period of 2005 to 2015. Exploratory: Data pertaining to rural and urban areas of the district covering all PHCs, UHCs and Towns were analyzed and interpreted. Outcome: Reduction in malaria incidence and scaling up of non chemical methods for control of malaria. Analysis: Percentage and proportions. Results: Area specific approach adopted in rural areas of Gandhinagar district by putting more emphasis on good surveillance, ensuring complete treatment to malaria cases within 24 hours and effective strategy for vector control mainly non chemical methods resulted in reducing Annual Parasitic Incidence (API) from 1.96 in 2005 to 0.17 in 2015 in Gandhinagar district. 226 villages (74.83%) out of 302 in the district are malaria free and only 9 villages are having API > 1.0. The district aims to achieve malaria elimination in the next five years. Conclusion: Gandhinagar district has made rapid stride towards malaria elimination in a cost effective manner by utilizing the available resources. The strategies adopted by the district can be replicated by other districts and States to achieve the goal of malaria elimination.展开更多
文摘Malaria control programme utilizing indoor residual spraying of chemical insecticide is only effective if a high coverage of targeted area is achieved. The effectiveness of the residual spraying, on the other hand, relies on the efficacy and residual activity of the insecticides applied, which to a certain extent are influenced by the nature of the sprayed surfaces. The bioefficacy of indoor residual-sprayed deltamethrin wettable granule (WG) formulation for the control of malaria was compared with the current dose of deltamethrin wettable powder (WP) in malaria endemic areas in Balai Ringin, Sarawak. Doses of 20 mg/m2 WP (control), 20 mg/m2 WG, 30 mg/m2 WG and 40 mg/m2 WG were sprayed separately on different surfaces namely, wooden, rough-bamboo, smooth-bamboo and brick surfaces. Residual activity of WP and WG formulations was tested against lab-bred Anopheles maculatus using WHO standard procedure. Deltamethrin at 30 mg/m2 WG exhibited the highest sustainable level of effectiveness against An. maculatus (An. maculatus mortality was between 95% - 100%) up to week 60 post-spraying when sprayed on smooth- bamboo surface. These results indicated that 30 mg/m2 WG could be an ideal concentration for controlling malaria vector effectively up to 15 months of which long-lasting residual spraying was envisaged. The usual two spraying cycles per year with 20 mg/m2 deltamethrin WP could be replaced with 30 mg/m2 deltamethrin WG since the long residual activity was achieved by employing a single spraying only.
文摘Early diagnosis and complete treatment are the most important components of the malaria control program, which have a direct bearing on prevention of mortality and reduction in the morbidity, therefore, follow-up of the patient treatment is an important aspect of monitoring disease in the community. Aims: To assess treatment compliance among confirmed malaria cases in Gandhinagar District and to determine the proportion of cure rate with complete treatment as per the national drug policy. Study Variables: Exploratory-rural and urban areas;outcome-compliance, cure rate. Analysis: Percentage, proportions. Results: Compliance among 192 subjects under the study conducted in 2008 i.e. confirmed that malaria cases were 88% even after the introduction of 14 day therapy for “Plasmodium vivax” cases, while 100% cure rate was observed on the follow-up till the 28th day among “P. vivax” and “P. falciparum” cases which helped in reducing malaria incidence in the rural area by 50% as compared to the preceding year of the study. Conclusion: Follow-up of the treatment given to malaria patients has enhanced compliance and cure rate, which in turn contributed towards interruption of transmission. Therefore, a better cure rate through the administration of effective antimalarial drugs as per the drug policy in combination with other containment measures is the right strategy to keep morbidity and mortality due to malaria under effective control.
文摘Background: Government of India has lunched the frame work for eliminating malaria from the country by 2030 [1] [2]. But progressive States like Gujarat has to achieve the target by 2024. The first step in this direction is to bring down the Annual Parasitic Incidence less than 1.0. Under National Vector Borne Disease Control Programme (NVBDCP) various activities for Vector control coupled with complete treatment to confirm malaria cases within 24 hours were given more focus and implemented diligently and effectively. Aim: To evaluate the progress of the efforts being undertaken for malaria elimination in Gandhinagar district. Design: Impact of malaria control efforts in Gandhinagar district covering all areas were studied in detail. Setting: Malaria prone villages of Gandhinagar district where preventive actions were undertaken in an integrated manner during the period of 2005 to 2015. Exploratory: Data pertaining to rural and urban areas of the district covering all PHCs, UHCs and Towns were analyzed and interpreted. Outcome: Reduction in malaria incidence and scaling up of non chemical methods for control of malaria. Analysis: Percentage and proportions. Results: Area specific approach adopted in rural areas of Gandhinagar district by putting more emphasis on good surveillance, ensuring complete treatment to malaria cases within 24 hours and effective strategy for vector control mainly non chemical methods resulted in reducing Annual Parasitic Incidence (API) from 1.96 in 2005 to 0.17 in 2015 in Gandhinagar district. 226 villages (74.83%) out of 302 in the district are malaria free and only 9 villages are having API > 1.0. The district aims to achieve malaria elimination in the next five years. Conclusion: Gandhinagar district has made rapid stride towards malaria elimination in a cost effective manner by utilizing the available resources. The strategies adopted by the district can be replicated by other districts and States to achieve the goal of malaria elimination.
