A new method was presented to discuss the respective roles of short- and long-range interactions in protein folding. It's based on an off-lattice model, which is also being called as toy model. Simulated annealing...A new method was presented to discuss the respective roles of short- and long-range interactions in protein folding. It's based on an off-lattice model, which is also being called as toy model. Simulated annealing algorithm was used to search its native conformation. When it is applied to analysis proteins 1agt and 1aho, we find that helical segment cannot fold into native conformation without the influence of long-range interactions. That's to say that long-range interactions are the main determinants in protein folding. Key words toy model - protein folding - simulated annealing algorithm - short and long range interactions CLC number O 242.28 - Q71 Foundation item: Supported by the National Natural Science Foundation of China((60301009)Biography: WANG Long-hui (1976-), female, Ph. D candidate, research direction: machine learning, bioinformatics.展开更多
The author of this article counts and analyzes the papers and authors printed in 2003 Wuhan University Journal of Natural Sciences by means of bibliometric statistical methods, of which the characteristics of papers a...The author of this article counts and analyzes the papers and authors printed in 2003 Wuhan University Journal of Natural Sciences by means of bibliometric statistical methods, of which the characteristics of papers and authors are expounded. The result shows that the ratio of reprinting of this journal has been increased and the areas where the authors come from and their organization scattered in the whole world are widened as well, which implies a better-known fame of the journal. Key words Wuhan University Journal of Natural Sciences - papers analysis - authors analysis - statistical analysis CLC number G 353.1 Biography: HU Min(1961-), famale, Associate professor, research direction; editing science and biochemistry.展开更多
文摘A new method was presented to discuss the respective roles of short- and long-range interactions in protein folding. It's based on an off-lattice model, which is also being called as toy model. Simulated annealing algorithm was used to search its native conformation. When it is applied to analysis proteins 1agt and 1aho, we find that helical segment cannot fold into native conformation without the influence of long-range interactions. That's to say that long-range interactions are the main determinants in protein folding. Key words toy model - protein folding - simulated annealing algorithm - short and long range interactions CLC number O 242.28 - Q71 Foundation item: Supported by the National Natural Science Foundation of China((60301009)Biography: WANG Long-hui (1976-), female, Ph. D candidate, research direction: machine learning, bioinformatics.
文摘The author of this article counts and analyzes the papers and authors printed in 2003 Wuhan University Journal of Natural Sciences by means of bibliometric statistical methods, of which the characteristics of papers and authors are expounded. The result shows that the ratio of reprinting of this journal has been increased and the areas where the authors come from and their organization scattered in the whole world are widened as well, which implies a better-known fame of the journal. Key words Wuhan University Journal of Natural Sciences - papers analysis - authors analysis - statistical analysis CLC number G 353.1 Biography: HU Min(1961-), famale, Associate professor, research direction; editing science and biochemistry.
