Recent studies have showed that factor seven activa-ting protease(FSAP)is a novel serine protease in humanplasma.Immunoreactivity for FSAP has been observed invascular endothelial cells,epithelial cells and macropha-g...Recent studies have showed that factor seven activa-ting protease(FSAP)is a novel serine protease in humanplasma.Immunoreactivity for FSAP has been observed invascular endothelial cells,epithelial cells and macropha-ges but FSAP-specific mRNA expression only exists inthe former two cells.FSAP has three epidermal growthfactor(EGF)domains,a kringle domain and a serineprotease domain.It circulates in the plasma as an inac-tive zymogen and undergoes autoactivation from a展开更多
文摘Recent studies have showed that factor seven activa-ting protease(FSAP)is a novel serine protease in humanplasma.Immunoreactivity for FSAP has been observed invascular endothelial cells,epithelial cells and macropha-ges but FSAP-specific mRNA expression only exists inthe former two cells.FSAP has three epidermal growthfactor(EGF)domains,a kringle domain and a serineprotease domain.It circulates in the plasma as an inac-tive zymogen and undergoes autoactivation from a
