The new synthetic route of (±)shikalkin 1 was developed. 3-(1-Hydroxy-4-methyl-3- pentenyl)-5, 8-dimethoxy-1-naphthol 8 was obtained from compound 3 in 10 steps. Then (±)shikalkin 1 was synthesized from 8 i...The new synthetic route of (±)shikalkin 1 was developed. 3-(1-Hydroxy-4-methyl-3- pentenyl)-5, 8-dimethoxy-1-naphthol 8 was obtained from compound 3 in 10 steps. Then (±)shikalkin 1 was synthesized from 8 in one step with reagents AgO/HNO3 in 1, 4-dioxane.展开更多
基金We thank the National Natural Science Foundation of China[30069004]for financial supports
文摘The new synthetic route of (±)shikalkin 1 was developed. 3-(1-Hydroxy-4-methyl-3- pentenyl)-5, 8-dimethoxy-1-naphthol 8 was obtained from compound 3 in 10 steps. Then (±)shikalkin 1 was synthesized from 8 in one step with reagents AgO/HNO3 in 1, 4-dioxane.
