The seasonal cycle of the climate of 9000 years before present was simulated with the IAP two-level atmospheric general circulation model. The incoming solar radiation was specified from the orbital parameters for 900...The seasonal cycle of the climate of 9000 years before present was simulated with the IAP two-level atmospheric general circulation model. The incoming solar radiation was specified from the orbital parameters for 9000 years ago. The boundary conditions of that time were prescribed to the present value because of the small differences between the two. The change in radiation makes temperature to be higher in summer and lower in winter over large areas of the land; and the increased temperature contrast between the land and the ocean strengthens the summer monsoon circulation and increases the precipitation over there. The asymmetry of temperature change between the Northern Hemisphere and the Southern Hemisphere and between summer and winter still exists, which agrees with that get from the previous perpetual experiments.展开更多
The preliminary analysis of climatic variation in China during the last 39 years has been made in this paper. The results show that although the global climate is getting warmer, some parts of China are cooling. The w...The preliminary analysis of climatic variation in China during the last 39 years has been made in this paper. The results show that although the global climate is getting warmer, some parts of China are cooling. The warming only occurs in Northeast, North and the west part of Northwest China while the areas between about 35°N and Nanling Mountain, east of the Tibetan Plateau in China are getting cooler. The cooling centers are located in Sichuan, the south part of Shaanxi and the north part of Yunnan respectively. According to the theory of greenhouse effect, there are much precipitation at low and high latitudes and less precipitation in middle latitude. However, the precipitation in the most parts of China has been decreased, especially in North and Northwest China.展开更多
To analyze the clinical effects after one year follow-up of LASIK for myopia.Methods According to the preoperative diopters of the myopia, patients, undergoing LASIK, were divided into three groups, group I : 140 eyes...To analyze the clinical effects after one year follow-up of LASIK for myopia.Methods According to the preoperative diopters of the myopia, patients, undergoing LASIK, were divided into three groups, group I : 140 eyes ( -1.25D～-6. 00D ), group Ⅱ : 203 eyes ( -6. 25D～ -10. 00D ), group Ⅲ : 226 eyes ( -10. 25D ～ -15. 00D ). The patients were followed up at least 1 year. Results By groups, the percentage of the uncorrected visual acuity equal or more than 1.0 were 94.29% , 80. 30% , 42.04% respectively.The residual refractive error within 0. 5D were 99. 29% , 85. 71% , 59. 70%. The spherical equivalent was stable 3 months after LASIK. The complications were few. Conclusion LASIK is a safe, effective and good predictable method for the treatment of myopia. It is one of the best choices to treat myopia below - 10. 00D.展开更多
1. Overview In June 2021, the 16th Workshop on Antarctic Meteorology and Climate (WAMC) and the 6th Year of Polar Prediction in the Southern Hemisphere (YOPP-SH) Meeting (http://polarmet.osu.edu/WAMC;021/) were held o...1. Overview In June 2021, the 16th Workshop on Antarctic Meteorology and Climate (WAMC) and the 6th Year of Polar Prediction in the Southern Hemisphere (YOPP-SH) Meeting (http://polarmet.osu.edu/WAMC;021/) were held online and hosted by the Polar Meteorology Group at Byrd Polar and Climate Research Center, The Ohio State University, Columbus,Ohio (Fig. 1).展开更多
Age-related macular degeneration(AMD)is a complicated disease that causes irreversible visual impairment.Increasing evidences pointed retinal pigment epithelia(RPE)cells as the decisive cell involved in the progress o...Age-related macular degeneration(AMD)is a complicated disease that causes irreversible visual impairment.Increasing evidences pointed retinal pigment epithelia(RPE)cells as the decisive cell involved in the progress of AMD,and the function of anti-oxidant capacity of PRE plays a fundamental physiological role.Nuclear factor erythroid 2 related factor 2(Nrf2)is a significant transcription factor in the cellular anti-oxidant system as it regulates the expression of multiple anti-oxidative genes.Its functions of protecting RPE cells against oxidative stress(OS)and ensuing physiological changes,including inflammation,mitochondrial damage and autophagy dysregulation,have already been elucidated.Understanding the roles of upstream regulators of Nrf2 could provide further insight to the OS-mediated AMD pathogenesis.For the first time,this review summarized the reported upstream regulators of Nrf2 in AMD pathogenesis,including proteins and miRNAs,and their underlying molecular mechanisms,which may help to find potential targets via regulating the Nrf2 pathway in the future research and further discuss the existing Nrf2 regulators proved to be beneficial in preventing AMD.展开更多
The idea of linear Diophantine fuzzy set(LDFS)theory with its control parameters is a strong model for machine learning and optimization under uncertainty.The activity times in the critical path method(CPM)representat...The idea of linear Diophantine fuzzy set(LDFS)theory with its control parameters is a strong model for machine learning and optimization under uncertainty.The activity times in the critical path method(CPM)representation procedures approach are initially static,but in the Project Evaluation and Review Technique(PERT)approach,they are probabilistic.This study proposes a novel way of project review and assessment methodology for a project network in a linear Diophantine fuzzy(LDF)environment.The LDF expected task time,LDF variance,LDF critical path,and LDF total expected time for determining the project network are all computed using LDF numbers as the time of each activity in the project network.The primary premise of the LDF-PERT approach is to address ambiguities in project network activity timesmore simply than other approaches such as conventional PERT,Fuzzy PERT,and so on.The LDF-PERT is an efficient approach to analyzing symmetries in fuzzy control systems to seek an optimal decision.We also present a new approach for locating LDF-CPM in a project network with uncertain and erroneous activity timings.When the available resources and activity times are imprecise and unpredictable,this strategy can help decision-makers make better judgments in a project.A comparison analysis of the proposed technique with the existing techniques has also been discussed.The suggested techniques are demonstrated with two suitable numerical examples.展开更多
文摘The seasonal cycle of the climate of 9000 years before present was simulated with the IAP two-level atmospheric general circulation model. The incoming solar radiation was specified from the orbital parameters for 9000 years ago. The boundary conditions of that time were prescribed to the present value because of the small differences between the two. The change in radiation makes temperature to be higher in summer and lower in winter over large areas of the land; and the increased temperature contrast between the land and the ocean strengthens the summer monsoon circulation and increases the precipitation over there. The asymmetry of temperature change between the Northern Hemisphere and the Southern Hemisphere and between summer and winter still exists, which agrees with that get from the previous perpetual experiments.
基金This work is supported by National Environment and Protect Agency under Program 891205
文摘The preliminary analysis of climatic variation in China during the last 39 years has been made in this paper. The results show that although the global climate is getting warmer, some parts of China are cooling. The warming only occurs in Northeast, North and the west part of Northwest China while the areas between about 35°N and Nanling Mountain, east of the Tibetan Plateau in China are getting cooler. The cooling centers are located in Sichuan, the south part of Shaanxi and the north part of Yunnan respectively. According to the theory of greenhouse effect, there are much precipitation at low and high latitudes and less precipitation in middle latitude. However, the precipitation in the most parts of China has been decreased, especially in North and Northwest China.
文摘To analyze the clinical effects after one year follow-up of LASIK for myopia.Methods According to the preoperative diopters of the myopia, patients, undergoing LASIK, were divided into three groups, group I : 140 eyes ( -1.25D～-6. 00D ), group Ⅱ : 203 eyes ( -6. 25D～ -10. 00D ), group Ⅲ : 226 eyes ( -10. 25D ～ -15. 00D ). The patients were followed up at least 1 year. Results By groups, the percentage of the uncorrected visual acuity equal or more than 1.0 were 94.29% , 80. 30% , 42.04% respectively.The residual refractive error within 0. 5D were 99. 29% , 85. 71% , 59. 70%. The spherical equivalent was stable 3 months after LASIK. The complications were few. Conclusion LASIK is a safe, effective and good predictable method for the treatment of myopia. It is one of the best choices to treat myopia below - 10. 00D.
基金the International Association of Meteorology and Atmospheric Science(IAMAS)/International Commission on Polar Meteorology(ICPM)Scientific Committee on Antarctic Research(SCAR)+2 种基金the World Meteorological Organization(WMO)for supporting these workshopsFinancial Support from the Office of Polar ProgramsNational Science Foundation(Grant No.NSF 1823135,1924730,192473,and 1951603)。
文摘1. Overview In June 2021, the 16th Workshop on Antarctic Meteorology and Climate (WAMC) and the 6th Year of Polar Prediction in the Southern Hemisphere (YOPP-SH) Meeting (http://polarmet.osu.edu/WAMC;021/) were held online and hosted by the Polar Meteorology Group at Byrd Polar and Climate Research Center, The Ohio State University, Columbus,Ohio (Fig. 1).
基金Supported by Capital Medical University Scientific Research Grant for Undergraduate Students(No.XSKY2023026).
文摘Age-related macular degeneration(AMD)is a complicated disease that causes irreversible visual impairment.Increasing evidences pointed retinal pigment epithelia(RPE)cells as the decisive cell involved in the progress of AMD,and the function of anti-oxidant capacity of PRE plays a fundamental physiological role.Nuclear factor erythroid 2 related factor 2(Nrf2)is a significant transcription factor in the cellular anti-oxidant system as it regulates the expression of multiple anti-oxidative genes.Its functions of protecting RPE cells against oxidative stress(OS)and ensuing physiological changes,including inflammation,mitochondrial damage and autophagy dysregulation,have already been elucidated.Understanding the roles of upstream regulators of Nrf2 could provide further insight to the OS-mediated AMD pathogenesis.For the first time,this review summarized the reported upstream regulators of Nrf2 in AMD pathogenesis,including proteins and miRNAs,and their underlying molecular mechanisms,which may help to find potential targets via regulating the Nrf2 pathway in the future research and further discuss the existing Nrf2 regulators proved to be beneficial in preventing AMD.
基金supported by the Deanship of Scientific Research,Vice Presidency for Graduate Studies and Scientific Research,King Faisal University,Saudi Arabia[Grant No.GRANT3862].
文摘The idea of linear Diophantine fuzzy set(LDFS)theory with its control parameters is a strong model for machine learning and optimization under uncertainty.The activity times in the critical path method(CPM)representation procedures approach are initially static,but in the Project Evaluation and Review Technique(PERT)approach,they are probabilistic.This study proposes a novel way of project review and assessment methodology for a project network in a linear Diophantine fuzzy(LDF)environment.The LDF expected task time,LDF variance,LDF critical path,and LDF total expected time for determining the project network are all computed using LDF numbers as the time of each activity in the project network.The primary premise of the LDF-PERT approach is to address ambiguities in project network activity timesmore simply than other approaches such as conventional PERT,Fuzzy PERT,and so on.The LDF-PERT is an efficient approach to analyzing symmetries in fuzzy control systems to seek an optimal decision.We also present a new approach for locating LDF-CPM in a project network with uncertain and erroneous activity timings.When the available resources and activity times are imprecise and unpredictable,this strategy can help decision-makers make better judgments in a project.A comparison analysis of the proposed technique with the existing techniques has also been discussed.The suggested techniques are demonstrated with two suitable numerical examples.
