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Inheritance and Innovation of Regional Cultures in Architectural Designs of Yichang
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作者 XU Jing MAO Mao ZHU Yuandong 《Journal of Landscape Research》 2023年第3期67-70,74,共5页
Against the background of outstanding traditional Chinese culture and the innovation-drivendevelopment strategy, this study analyzed regional cultures of Yichang where ancient Ba and Chu culturesmet and blended, propo... Against the background of outstanding traditional Chinese culture and the innovation-drivendevelopment strategy, this study analyzed regional cultures of Yichang where ancient Ba and Chu culturesmet and blended, proposed regional architectural designs adapted to modern conditions, fully clarified thedesign concepts of “deeply exploring, highly condensing, making the past serve the present, inheriting andinnovating” through analyzing the design cases in many regional architectural projects. The paper aimedat further inheriting and developing the outstanding traditional Chinese cultures, and provided theoreticalreferences for future designs. 展开更多
关键词 Regional culture Ba-Chu culture Traditional architecture Inheritance and innovation
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Analysis of public psychological status and related factors in Yichang during the closing of initial Covid-19
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作者 Ling Wang Cai-Xia Liu 《Psychosomatic Medicine Research》 2023年第2期17-21,共5页
Objective:To investigate the psychological health status and influencing factors of the public during the epidemic of Covid-19 in Yichang,Hubei,and provide evidence for future psychological intervention.Methods:This s... Objective:To investigate the psychological health status and influencing factors of the public during the epidemic of Covid-19 in Yichang,Hubei,and provide evidence for future psychological intervention.Methods:This study used snowball sampling,SCL-90 scale,and SSRS to conduct a questionnaire survey of 563 residents.Results:The state of public mental health during the closure of Covid-19 was worse than the national norm.Gender,age,and culture have an impact on mental health.There was a significant correlation between social support and the level of mental health.The effects of various variables on the public mental state from big to small:objective support,gender,occupation.Conclusion:The psychological problems of the public during the closure of the city of Covid-19 deserve attention.According to different influencing factors,corresponding measures should be implemented to improve the public’s psychological endurance and respond to public health emergencies with a healthy mentality. 展开更多
关键词 Covid-19 psychological status social support
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Chitinozoans from the Fenxiang Formation (Early Ordovician) of Yichang,Hubei Province,China 被引量:5
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作者 CHEN Xiaohong Florentin PARIS ZHANG Miao 《Acta Geologica Sinica(English Edition)》 SCIE CAS CSCD 2008年第2期287-294,共8页
Chitinozoans collected from upper Tremadocian to lower Floian strata of Chenjiahe section, Yichang, western Hubei, China comprise six species belonging respectively to the genera Euconochitina including a new species,... Chitinozoans collected from upper Tremadocian to lower Floian strata of Chenjiahe section, Yichang, western Hubei, China comprise six species belonging respectively to the genera Euconochitina including a new species, Euconochitina fenxiangensis, Lagenochitina and Bursachitina, together with Desmochitina sp. and Eremochitina sp. The chitinozoan succession across the interval is correlated with relevant conodont and chitinozoan biozones and two new regional chitinozoan biozones, the Lagenochitina destombesi Biozone and the Euconochitina symmetrica Biozone are proposed based on their stratigraphic ranges in the Fenxiang to Honghuayuan formations in the Chenjiahe section. 展开更多
关键词 Early Ordovician CHITINOZOA SYSTEMATICS BIOZONATION western Hubei China
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A proposed GSSP for the base of the Middle Ordovician Series: the Huanghuachang section,Yichang, China 被引量:14
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作者 XiaofengWang SvendStouge +6 位作者 Bernd-D.Erdtmann XiaohongChen ZhihongLi ChuanshangWang QingluanZeng ZhiqiangZhou HuimingChen 《Episodes》 SCIE 2005年第2期105-117,共13页
The Huanghuachang section near Yichang, southern China meets the requirements of Global Stratotype Section and Point (GSSP) for the base of the Middle Ordovician Series and the yet-to-be-named third stage of the Ordov... The Huanghuachang section near Yichang, southern China meets the requirements of Global Stratotype Section and Point (GSSP) for the base of the Middle Ordovician Series and the yet-to-be-named third stage of the Ordovician System (or lower stage of Middle Ordovician Series). The conodont succession at the section is complete across the Lower to Middle Ordovician series boundary and several excellent phylogenetic lineages of Baltoniodus, Trapezognathus, Periodon, and Microzarkodina are represented. The definition of the base of the Middle Ordovician is proposed to be the first appearance datum (FAD) of Baltoniodus? triangularis in the section. It is followed closely by the FAD of Microzarkodina flabellum, which is taken as a reasonable proxy for the boundary. This level approximates the boundary between the lower and upper intervals of the Azygograptus suecicus graptolite Biozone, and nearly coincides with the base of the Belonechitina henryi chitinozoan Biozone.The proposed GSSP for the base of the international Middle Ordovician Series is located in a roadside exposure at the base of Bed (SHod) 16, 10.57 m above the base of the Dawan Formation in the measured Huanghuachang section near Yichang City, southern China. The same faunal succession is also recorded from the Chenjiahe (formerly Daping) section, 5 km to the north of the Huanghuachang section. The proposed boundary horizon can be recognized and correlated globally with high precision in both relatively shallow-water carbonate facies as well as in deep-water graptolite facies. 展开更多
关键词 GSSP 奥陶纪 宜昌市 地质分层研究 地形特征
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Research on the different content of weathered sand influence on expansive characteristic of a highway expansive soil in Yichang 被引量:1
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作者 Yang Jun Li Xinchun +2 位作者 Zhang Guodong Tang Yunwei Xie Zhigang 《Engineering Sciences》 EI 2013年第5期84-90,共7页
This paper aims at widespread presence of expansive soil which can be obtained in the project from Xiaoxita to Yaqueling first-class highway rebuilding engineering in Yichang City of Hubei Province and weathered sand ... This paper aims at widespread presence of expansive soil which can be obtained in the project from Xiaoxita to Yaqueling first-class highway rebuilding engineering in Yichang City of Hubei Province and weathered sand which can be made full use locally,many experiments have been made. Compaction experiments and expansibility index indoor experiments of undisturbed expansive soil and expansive soil mixed with sand ranging from 10 % to 50 % have been made. Through the test mixing undisturbed expansive soil with different content of weathered sand,it can change the expansive soil water characteristics and compaction characteristics. It can influence the expansibility of the expansive soil index and significantly inhibit the expansibility of the expansive soil and reach the standard of roadbed filler. 展开更多
关键词 膨胀特性 膨胀土 风化砂 宜昌市 高速公路 公路改建工程 室内实验 可扩展性
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High serum lactate dehydrogenase and dyspnea:Positive predictors of adverse outcome in critical COVID-19 patients in Yichang 被引量:1
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作者 Xiao-Ting Lv Yong-Ping Zhu +7 位作者 Ai-Guo Cheng Yong-Xu Jin Hai-Bo Ding Cai-Yun Wang Shu-Yu Zhang Gong-Ping Chen Qing-Quan Chen Qi-Cai Liu 《World Journal of Clinical Cases》 SCIE 2020年第22期5535-5546,共12页
BACKGROUND Coronavirus disease 2019(COVID-19)caused by the severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)outbreak in China,constitutes a Public Health Emergency of International Concern.It is well known t... BACKGROUND Coronavirus disease 2019(COVID-19)caused by the severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)outbreak in China,constitutes a Public Health Emergency of International Concern.It is well known that COVID-19 patients may have increased serum lactate dehydrogenase(LDH)levels in the early stage.The clinical changes in LDH may have predictive value in disease evolution and prognosis in critically ill COVID-19 patients.AIM To examine serum LDH and clinical characteristics in patients with COVID-19 and their predictive value for prognosis.METHODS This retrospective study analyzed the clinical data of forty-seven critical COVID-19 patients in the intensive care unit of the Third People's Hospital of Yichang City from January 27 to March 25,2020 and divided them into survivors and nonsurvivors.The patients were diagnosed according to the World Health Organization interim guidance and critical cases met any one of the following criteria:Respiratory failure and required mechanical ventilation,the occurrence of shock,and the combined failure of other organs that required intensive care unit monitoring and treatments,according to the diagnostic criteria of critical COVID-19.Clinical data including symptoms,detection of SARS-CoV-2,chest computed tomography(CT)images,changes in serum LDH in different clinical phases,and prognosis were collected.Statistical analysis of the data was performed.Continuous variables were expressed as median(interquartile range)and compared with the Mann-Whitney U test.Categorical variables were compared with the Chi-square test.Survival data were analyzed using Kaplan-Meier survival curves and log-rank tests.RESULTS According to chest CT images,we observed the alveolitis and fibrosis stages in all critical patients in this study.Most non-survivors died in the fibrosis stage.Nonsurvivors had fewer days of hospitalization,shorter disease duration,shorter duration of alveolitis and fibrosis,and had dyspnea symptoms at disease onset(P=0.05).Both first and lowest LDH values in the alveolitis stage were more pronounced in non-survivors than in survivors(449.0 U/L vs 288.0 U/L,P=0.0243;445.0 U/L vs 288.0 U/L,P=0.0199,respectively),while the first,lowest and highest values of serum LDH in non-survivors were all significantly increased compared to survivors in the fibrosis phase(449.0 U/L vs 225.5 U/L,P=0.0028;432.0 U/L vs 191.0 U/L,P=0.0007;1303.0 U/L vs 263.5 U/L,P=0.0001,respectively).The cut-off points of first LDH values in the alveolitis and fibrosis phase for distinction of non-survivors from survivors were 397.0 U/L and 263.0 U/L,respectively.In the fibrosis stage,non-survivors had more days with high LDH than survivors(7.0 d vs 0.0 d,P=0.0002).Importantly,patients with high LDH had a significantly shorter median survival time than patients with low LDH in the alveolitis phase(22.0 d vs 36.5 d,P=0.0002),while patients with high LDH also had a significantly shorter median survival time than patients with low LDH in the fibrosis phase(27.5 d vs 40.0 d,P=0.0008).The proportion of non-survivors with detectable SARS-CoV-2 until death in the alveolitis stage was significantly increased compared with that in the fibrosis stage(100%vs 35.7%,P=0.0220).CONCLUSION High LDH and dyspnea symptoms were positive predictors of an adverse outcome in critical COVID-19.The rapid progressive fibrosis stage was more perilous than the alveolitis stage,even if SARS-CoV-2 is undetectable. 展开更多
关键词 COVID-19 SARS-CoV-2 Lactate dehydrogenase Pulmonary fibrosis DYSPNEA Overall survival
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Research and Practice of Agricultural Cultural Tourism and Vernacular Landscape Design under the Background of Rural Revitalization:A Case Study of Jinse Time Agricultural Park in Fu’an Village,Dianjun District,Yichang
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作者 MAO Mao ZHOU Wenyan 《Journal of Landscape Research》 2021年第6期37-42,47,共7页
Under the background of urban-rural integration and rural revitalization,based on the theory of rural landscape design in the field of landscape architecture,the specific design ideas and implementation plans of rural... Under the background of urban-rural integration and rural revitalization,based on the theory of rural landscape design in the field of landscape architecture,the specific design ideas and implementation plans of rural revitalization and leisure agricultural tourism in Fu’an Village,Dianjun District with rich ecological resources and agricultural culture,and the practice of promoting rural economic revitalization and leisure agricultural tourism with cultural tourism industry are discussed to provide reference for the beautiful rural construction and regional architectural design in Yichang and surrounding areas. 展开更多
关键词 Rural revitalization Rural culture Leisure agriculture Economic revitalization
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Rural Revitalization Construction and Local Landscape Design:A Case Study of Qili Village,Aijia Town,Dianjun District,Yichang
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作者 MAO Mao SU Lingjun 《Journal of Landscape Research》 2022年第2期33-38,共6页
In the context of the 2021 No.1 central document released and the year when the rural revitalization was first launched, Qili Village of Aijia Town with rich natural landscape resources, convenient location and transp... In the context of the 2021 No.1 central document released and the year when the rural revitalization was first launched, Qili Village of Aijia Town with rich natural landscape resources, convenient location and transportation is taken as an example. Combining ecological design concept and local landscape design idea of landscape architecture specialty, and taking “one core, two main lines, five nodes,and comprehensive experience” as master plan, it tries to build regional local landscape of “one village, one product” and condense the “nostalgia” artistic conception of Qili Village as the core, protect and repair the livable ecological environment, improve infrastructure construction, create high-quality leisure agricultural tourism projects, and attract talents to return home and start businesses. It will fully realize the “five revitalization” of Qili Village, thereby providing theoretical and practical reference for rural revitalization in Yichang and its surrounding areas. 展开更多
关键词 Rural vitalization Leisure agricultural tourism Ecological environment Nostalgic artistic conception
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Flame Burn Injury in Yichang of China:the Trends,Complications,and Risk Factor Analysis
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作者 Lixia WEN Weimin WU +4 位作者 Yunbo JIN Bo ZHOU Lei WU Yapeng LIU Ying HU 《Chinese Journal Of Plastic and Reconstructive Surgery》 2021年第1期17-26,共10页
Background A flame burn is an injury of body tissues,including respiratory tract damage,due to exposure to a flame or its dense smoke.Flame burns cause some of the most physically and psychologically devastating forms... Background A flame burn is an injury of body tissues,including respiratory tract damage,due to exposure to a flame or its dense smoke.Flame burns cause some of the most physically and psychologically devastating forms of trauma.Compared to scald burns,flame burn patients have a higher mortality rate and a higher frequency of multiorgan failure.The purpose of this research was to investigate the trends,complications,and mortality risk factors of flame burns at the Department of Plastic and Burn Surgery(DPBS)of the People’s Hospital of China Three Gorges University(PHCTGU).Methods A retrospective analysis of 48 flame burn patients—accounting for 8.3%of the 576 burn victims admitted for burns at the PHCTGU from February 1,2010,to September 30,2019—was performed after collecting information from the Burns Registry of the said hospital.Results The proportion of patients with flame burns was 8.3%(n=48).The mean total body surface area(TBSA)affected was 27.6%.The mean duration of hospitalization was 32.5 days.The etiologies of the flame burns were as follows:gas explosions(21,43.8%),ethanol(8,16.7%),charcoal fire(7,14.6%),petrol explosions(4,8.3%),wooden houses(4,8.3%),and others,including dust,cigarette lighter,and burning incense,accounting for 8.3%of cases(4).Finally,42(87.5%)patients were treated and discharged,and 6(12.5%)patients died.Complications included scarring in 38(90.5%)patients,severe scar contractures on different parts of the body in 25(60.0%)patients,scar ulcer in 6(14.3%)patients,keloids in 3(7.1%)patients,and scar cancer in 1(2.4%)patient.Multiple complications occurred in the same patient.The only risk factor for mortality that was identified was TBSA(P=0.043).Conclusions Our study revealed that a small population(8.3%)was injured by flame burns,but 6 deaths were recorded.Society must continually enhance safeguard procedures to flames and strengthen education to protect life and avoid severe complications. 展开更多
关键词 Flame burn TREND COMPLICATIONS Mortality risk factors
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改进贝叶斯网络模型在起重作业人机交互差错风险分析中的应用 被引量:1
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作者 晋良海 闫月蓉 +3 位作者 陈颖 邵波 陈述 陈云 《安全与环境学报》 CAS CSCD 北大核心 2024年第1期213-220,共8页
为量化分析起重作业人机交互差错风险,根据安全工效学原理及安全技术规范将起重作业人、机、环相关影响因素作为根节点,按照事故致因层次关联关系确定子节点,构建起重作业人机交互差错的3层级贝叶斯网络模型(Bayesian Network, BN);基... 为量化分析起重作业人机交互差错风险,根据安全工效学原理及安全技术规范将起重作业人、机、环相关影响因素作为根节点,按照事故致因层次关联关系确定子节点,构建起重作业人机交互差错的3层级贝叶斯网络模型(Bayesian Network, BN);基于模糊集理论,采用认知可靠性与失误分析方法(Cognitive Reliability and Error Analysis Method, CREAM),厘定贝叶斯网络父节点失效概率以及中间节点条件概率;利用逆向推理仿真技术分析起重作业人机交互差错发生的因果链,探究起重伤害事故发生的人机交互差错风险。结果表明:起重作业人机交互差错最可能致因链为起重设备安全检查不到位→管理人员失误→人员操作失误→起重伤害事故发生;单因素失效条件下,起重作业人机交互差错风险概率呈线性增长趋势;在多因素失效条件下,一级节点因素失效概率愈大则人机交互差错效应愈显著,且呈现非线性增长态势。 展开更多
关键词 安全工程 起重作业 人机交互差错 贝叶斯网络(BN) 认知可靠性与失误分析方法(CREAM)
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The Spectrum and Age-Sex Patterns Among Outpatients with Allergic Diseases—Yichang City,Hubei Province,China,2018–2021
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作者 Jinyi Wang Mingwei Sun +3 位作者 Guoxing Li Dapeng Yin Chi Hu Jinfang Sun 《China CDC weekly》 SCIE CSCD 2023年第31期681-686,I0001,共7页
What is already known about this topic?Allergic diseases have affected an estimated 40%of the population in China.However,our understanding of the full spectrum of these diseases remains insufficient.What is added by ... What is already known about this topic?Allergic diseases have affected an estimated 40%of the population in China.However,our understanding of the full spectrum of these diseases remains insufficient.What is added by this report?Between 2018 and 2021,Yichang City documented 625,929 outpatient visits mainly related to skin and mucous membrane allergies(77.90%)and allergic respiratory conditions(19.64%).In 2021,the occurrence of outpatient visits for conditions such as allergic rhinitis,acute atopic conjunctivitis,and atopic dermatitis increased.The demographic analysis revealed that male patients comprised the majority of the under 18 age bracket(56.05%),while female patients were predominantly represented in the 18 to 65 age bracket(61.79%).What are the implications for public health practice?This constitutes the first analysis of the spectrum of allergic diseases,utilizing regional outpatient data,which has substantial implications for understanding the disease burden. 展开更多
关键词 utilizing analysis HUBEI
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动态场景的三维重建研究综述 被引量:1
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作者 孙水发 汤永恒 +4 位作者 王奔 董方敏 李小龙 蔡嘉诚 吴义熔 《计算机科学与探索》 CSCD 北大核心 2024年第4期831-860,共30页
随着静态场景三维重建算法的不断成熟,动态场景三维重建算法成为近年来的研究热点和研究难点。现有的静态场景三维重建算法对静止的对象有较好的重建效果,一旦场景中对象出现变形或者是相对运动,其重建效果不太理想,因此发展对动态场景... 随着静态场景三维重建算法的不断成熟,动态场景三维重建算法成为近年来的研究热点和研究难点。现有的静态场景三维重建算法对静止的对象有较好的重建效果,一旦场景中对象出现变形或者是相对运动,其重建效果不太理想,因此发展对动态场景的三维重建研究工作是相当重要的。简要介绍三维重建的相关概念及基本知识、静态场景三维重建和动态场景三维重建的研究分类及研究现状;全面总结了动态场景三维重建研究最新进展,将动态场景三维重建按照基于RGB数据源的动态三维重建和基于RGB-D数据源的动态三维重建进行分类,其中RGB数据源下又可划分为基于模板的动态三维重建、基于非刚性运动恢复结构的动态三维重建和RGB数据源下基于学习的动态三维重建,RGB-D数据源下主要总结归纳基于学习的动态三维重建,对各类典型重建算法进行了介绍和对比分析;介绍了动态场景三维重建在医学、智能制造、虚拟现实与增强现实、交通等领域的应用;提出了动态场景三维重建的未来研究方向,并对这个快速发展领域中的各个方向研究进行了展望。 展开更多
关键词 动态场景三维重建 模板先验 运动恢复结构 深度学习
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基于麻雀搜索算法的微电网分层优化调度 被引量:1
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作者 吴成明 邢博洋 李世春 《南方电网技术》 CSCD 北大核心 2024年第2期115-123,共9页
为综合考虑微电网供给侧和需求侧的利益,建立了微电网分层优化模型;上层以净负荷成本和用电满意度为目标优化负荷曲线,下层以运行成本和环境成本为目标优化各单元出力,并选择麻雀搜索算法(SSA)求解这类复杂优化问题。针对SSA易陷入局部... 为综合考虑微电网供给侧和需求侧的利益,建立了微电网分层优化模型;上层以净负荷成本和用电满意度为目标优化负荷曲线,下层以运行成本和环境成本为目标优化各单元出力,并选择麻雀搜索算法(SSA)求解这类复杂优化问题。针对SSA易陷入局部最优的问题,提出一种改进麻雀搜索算法(ISSA),改进了发现者搜索方式,引入了变异、贪婪策略;并且加入非支配排序和轮盘赌法将ISSA改进为多目标算法。算例结果表明可转移负荷占比为10%时能够协调微电网供需两侧的利益;对比ISSA与SSA、粒子群算法(PSO)、鸡群算法(CSO)和灰狼算法(GWO)的迭代结果,证明ISSA具有良好的寻优效果和稳定性。 展开更多
关键词 微电网 需求响应 分层优化 麻雀搜索算法(SSA)
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泥岩卸荷损伤-水次序作用下的劣化规律研究 被引量:1
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作者 王宇 夏厚磊 +1 位作者 茆苏徽 闫亮 《岩土工程学报》 EI CAS CSCD 北大核心 2024年第2期385-395,共11页
工程开挖建设导致软岩形成卸荷损伤,其在水-岩作用下的劣化特征与卸荷损伤程度密切相关。以巴东地区红层泥岩为研究对象,设计进行了泥岩卸荷损伤模拟试验,随后对卸荷损伤泥岩试样进行水-岩作用试验,结果显示:卸荷损伤导致泥岩局部矿物... 工程开挖建设导致软岩形成卸荷损伤,其在水-岩作用下的劣化特征与卸荷损伤程度密切相关。以巴东地区红层泥岩为研究对象,设计进行了泥岩卸荷损伤模拟试验,随后对卸荷损伤泥岩试样进行水-岩作用试验,结果显示:卸荷损伤导致泥岩局部矿物颗粒形态破坏、微裂缝发育,在后续水-岩作用下颗粒间胶结程度持续弱化,孔隙、裂缝进一步扩展。宏细观参数随水-岩作用时间的增长,其中质量m呈现先上升后骤然下降再趋于稳定的趋势,纵波波速P呈现先减少后上升的趋势,体积应变εv呈现逐渐增大的趋势,分形维数K呈逐渐增长的趋势;且各参数的增长速率均随卸荷损伤程度D的增大呈幂函数增加,当D≥0.49时,各参数的增长速率急剧增大;确定以质量、纵波波速、体积应变和分形维数作为与水反应系统的变量,并运用非线性动力学理论建立了水-岩作用下的泥岩劣化模型,并验证了模型的合理性。研究结果表明所建模型能表征卸荷损伤泥岩在水-岩作用下的宏细观特征参数变化趋势提供一定理论参考。 展开更多
关键词 卸荷损伤 水-岩作用 宏细观参数 劣化规律 非线性动力学模型
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魔芋甘露低聚糖增强肠道屏障功能改善酒精性中枢神经损伤的实验研究 被引量:1
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作者 陈晶晶 钟文艳 +2 位作者 沈文卓 肖莉 袁成福 《中国药理学通报》 CAS CSCD 北大核心 2024年第3期447-454,共8页
目的慢性酒精摄入导致的大脑过度神经炎症是中枢神经损伤的重要危险因素。本实验主要研究魔芋甘露低聚糖(Konjac mannan oligosaccharides,KMOS)保护酒精喂养小鼠中枢神经炎症的作用及其机制。方法C57BL/6J小鼠采用Gao-binge法制备慢性... 目的慢性酒精摄入导致的大脑过度神经炎症是中枢神经损伤的重要危险因素。本实验主要研究魔芋甘露低聚糖(Konjac mannan oligosaccharides,KMOS)保护酒精喂养小鼠中枢神经炎症的作用及其机制。方法C57BL/6J小鼠采用Gao-binge法制备慢性酒精喂养小鼠模型,同时使用不同剂量的KMOS灌胃干预,喂养6周。评估脑组织皮层和海马区域神经元损伤和小胶质细胞活化情况,观察结肠组织损伤情况和炎症反应,检测血清LPS浓度。体外使用LPS直接刺激Caco-2细胞制备肠黏膜损伤模型。结果慢性酒精的摄入可导致小鼠大脑神经元损伤,而不同剂量的KMOS均能有效降低酒精喂养小鼠脑组织中小胶质细胞的活化状态,降低NLRP3炎性小体活化导致的炎性因子表达,减轻神经元受损。对结肠组织的分析结果表明,KMOS的使用有效地降低了酒精喂养小鼠外周血中内毒素LPS的浓度,减轻酒精喂养小鼠结肠组织的病理损伤和炎性反应,增强肠道组织Occludin表达。体外实验也显示,KMOS能显著抑制酒精暴露下Caco-2细胞的炎性反应,显著提高Occludin表达水平。结论KMOS的使用可有效的抑制酒精摄入导致的肠道炎症,修复肠道屏障,减少肠道LPS进入脑组织,降低小胶质细胞活化导致的过度神经炎症反应,进而改善脑神经元损伤。KMOS具有预防酒精性神经损伤的潜力。 展开更多
关键词 魔芋甘露低聚糖 酒精 LPS 小胶质细胞 OCCLUDIN NLRP3炎症小体
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基于凸型线圈双向电磁力加载的管件电磁翻边成形 被引量:1
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作者 邱立 罗宝妮 +2 位作者 何琴 刘洪池 李智 《热加工工艺》 北大核心 2024年第9期152-158,共7页
传统线圈电磁力单一导致管件翻边角度不佳。本文提出采用凸型线圈管件翻边的方法,通过设计新型线圈,同时为管件翻边提供双向电磁力。建立了两组模型,分别采用传统线圈和凸型线圈驱动管件发生电磁翻边成形,探讨分析了两组管件模型翻边成... 传统线圈电磁力单一导致管件翻边角度不佳。本文提出采用凸型线圈管件翻边的方法,通过设计新型线圈,同时为管件翻边提供双向电磁力。建立了两组模型,分别采用传统线圈和凸型线圈驱动管件发生电磁翻边成形,探讨分析了两组管件模型翻边成形过程中的电磁力矢量以及变形速率的变化。结果表明,凸型线圈加载管件翻边时提供的双向电磁力极大地提高了管件变形的流动性,从而提高了翻边角度。此外,相同放电参数下基于凸型线圈的管件翻边角度较传统线圈提高了1.25倍。显然,新型线圈能够在一定程度上改善管件电磁翻边的质量问题,为电磁翻边成形的工业化应用提供更多可能。 展开更多
关键词 管件 电磁翻边 凸型线圈 双向电磁力 翻边角度
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库水作用下滑坡土体渗流与蠕变耦合试验研究 被引量:1
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作者 王力 孙文铎 +3 位作者 王世梅 胡秋芬 陈玙珊 南芳芸 《长江科学院院报》 CSCD 北大核心 2024年第2期128-134,共7页
水库滑坡变形具有显著的渗流与蠕变耦合效应。为此,采用自主研发的渗流与蠕变耦合三轴试验仪,分别开展了渗流对蠕变的影响以及变形对渗流的影响试验研究,并改进GDS三轴仪完成了高精度控制和量测的渗流与蠕变耦合试验。结果表明:渗流作用... 水库滑坡变形具有显著的渗流与蠕变耦合效应。为此,采用自主研发的渗流与蠕变耦合三轴试验仪,分别开展了渗流对蠕变的影响以及变形对渗流的影响试验研究,并改进GDS三轴仪完成了高精度控制和量测的渗流与蠕变耦合试验。结果表明:渗流作用下,土样体积变形随时间先逐渐增大后缓慢减小,主要原因是超孔隙水压力导致围压卸荷,使得土样产生回弹变形,但渗透压力持续作用于土体,使得土样体积持续缓慢减小;获取了渗流过程中土样体积的变化结果,分别建立了渗流开始前试样e-k(孔隙比-渗透系数)关系曲线及渗流稳定后试样e-k关系曲线,结果表明考虑变形影响的e-k关系曲线更能反映土体的流固耦合效应。研究成果可望为水库滑坡变形演化预测提供更加科学严密的理论和方法。 展开更多
关键词 水库滑坡 蠕变 渗流 流固耦合 体积应变
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“双固一通”针法治疗肥胖型多囊卵巢综合征的临床疗效观察 被引量:1
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作者 李玉娥 彭家龙 +4 位作者 屈勇 田寅桂 向剑英 张继红 邓晓燕 《江汉大学学报(自然科学版)》 2024年第2期20-27,共8页
目的探讨“双固一通”针法对肥胖型多囊卵巢综合征(PCOS)患者体重、糖脂代谢、月经情况的影响。方法选取肥胖型PCOS患者65例随机分为“双固一通”组和对照组,分别予以“双固一通”针法及二甲双胍口服治疗,连续治疗3个月经周期。治疗期... 目的探讨“双固一通”针法对肥胖型多囊卵巢综合征(PCOS)患者体重、糖脂代谢、月经情况的影响。方法选取肥胖型PCOS患者65例随机分为“双固一通”组和对照组,分别予以“双固一通”针法及二甲双胍口服治疗,连续治疗3个月经周期。治疗期间两组均采取生活方式管理。观察两组患者治疗前后糖脂代谢(空腹血糖、胰岛素、HOMA-IR指数、甘油三酯)、体质量指数(BMI)与腰臀比(WHR)和血清激素水平(LH、T、E2、FSH)的变化。结果“双固一通”组能降低患者血糖、空腹胰岛素水平,HOMA-IR指数、甘油三酯水平、BMI、WHR水平(P<0.05)、及血清LH、T、E2含量显著降低(P<0.01)。改善空腹血糖、胰岛素、甘油三酯、BMI、WHR、LH、E2方面疗效均优于对照组。结论“双固一通”针法治疗肥胖型PCOS疗效肯定,较二甲双胍更具优势,值得推广应用. 展开更多
关键词 双固一通 多囊卵巢综合征 肥胖 针刺
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海温异常对长江流域夏季典型旱涝的影响研究 被引量:1
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作者 张灵 熊开国 +1 位作者 郭广芬 张俊 《人民长江》 北大核心 2024年第4期118-124,共7页
为研究长江流域夏季旱涝特征及其与海温异常之间的关联性,基于中国326个气象站降水量、NCEP/NCAR再分析资料等,采用合成分析、EOF分解等方法,分析了长江流域夏季典型旱涝年的降水分布、同期大气环流及前期海温特征,并以2018年为例,初步... 为研究长江流域夏季旱涝特征及其与海温异常之间的关联性,基于中国326个气象站降水量、NCEP/NCAR再分析资料等,采用合成分析、EOF分解等方法,分析了长江流域夏季典型旱涝年的降水分布、同期大气环流及前期海温特征,并以2018年为例,初步揭示了2018年前期海温异常对大气环流的可能影响。结果表明:①长江流域夏季典型旱年,仅嘉陵江和岷沱江会表现出局部偏涝,全国为典型的Ⅰ类雨型,多雨区位于黄河流域及以北地区。前期冬季赤道太平洋表现出类拉尼娜的东冷西暖分布,同时黑潮区海温偏低,西风漂流区海温偏暖。受多海域协同作用,同期欧亚环流场上自西北向东南呈现出“+-+”三极型分布,东亚地区为自北向南“-+-”的EAP负位相。长江流域典型涝年,全国多为典型的Ⅱ类和Ⅲ类雨型,环流及海温呈现出相反特征。②2018年为典型的长江中下游偏旱年,仅在岷沱江降水偏多近3成,为历史第4多,与长江流域夏季降水的主模态正位相类似,解释方差达24%。③2018年前冬出现弱拉尼娜、春末夏初西风漂流区异常偏暖、NAT异常正位相,三者共同作用,使得东亚副热带西风急流偏北,东亚沿岸出现EAP负位相,大陆热低压明显偏强,东亚夏季风为1961年以来最强,同时副高脊线最北,造成夏季降水主雨带北推至华北、西北地区,岷沱江、嘉陵江异常多,而长江中下游异常少,为典型的Ⅰ类雨型。研究成果可为长江流域旱涝预测、水资源调度提供参考。 展开更多
关键词 夏季典型旱涝 海温异常 Ⅰ类雨型 拉尼娜 西风漂流区 长江流域
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湖北宜昌磷矿伴生稀土元素分布规律、赋存状态及其开发利用前景分析 被引量:1
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作者 刘林 王大钊 +1 位作者 陈爱章 蔡雄威 《中国地质》 CAS CSCD 北大核心 2024年第2期525-546,共22页
【研究目的】湖北省宜昌磷矿中伴生有稀土元素,研究其分布规律及赋存状态,对稀土元素的回收利用具有重要意义,其作为伴生矿产的综合利用将成为未来稀土矿的重要来源。【研究方法】本文以含稀土磷块岩为主要研究对象,在系统取样的基础上... 【研究目的】湖北省宜昌磷矿中伴生有稀土元素,研究其分布规律及赋存状态,对稀土元素的回收利用具有重要意义,其作为伴生矿产的综合利用将成为未来稀土矿的重要来源。【研究方法】本文以含稀土磷块岩为主要研究对象,在系统取样的基础上,开展岩矿鉴定、全岩地球化学分析、XRD衍射分析、SEM观察、LA-ICP-MS测试等工作。【研究结果】磷块岩中稀土元素总量ΣREE+Y为63.5×10^(-6)~271.8×10^(-6),不同层位或不同岩性的磷块岩中稀土元素含量有所差异。【结论】稀土元素含量受岩性控制明显,由白云岩→白云质磷块岩→致密块状磷矿石→泥质条带磷块岩→泥岩,含量逐渐升高。微量元素反映出宜昌磷矿的古气候以干热为主,西北部略表现出温暖湿润特点;Ce异常、V/Ni和Y/Ho比值反映海水中EH条件从底部到顶部,即从Ph22成磷期到Ph13成磷期,形成水体环境逐渐氧化。宜昌磷矿中稀土元素总量整体较低,且泥岩较磷块岩中含量高,表明吸附态稀土较类质同象稀土含量高。宜昌伴生稀土磷矿资源丰富,利用合理的技术对稀土元素进行综合回收,对宜昌磷矿资源的合理利用和经济发展有重要意义。 展开更多
关键词 磷矿 伴生稀土 分布规律 赋存状态 开发利用前景 矿产勘查工程 宜昌 湖北
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