A New Talent Cultivation Model Under Open-source Environment:A Case Study at Zhejiang University

The open-source movement profoundly impacts the development of computer education.The current requirements for postgraduate cultivation in Chinese universities mainly include publishing papers,applying for patents,winning awards,and conducting research projects,which demonstrate the capabilities of students when they graduate from university.However,in today’s prevalent open-source culture,these types of assessments are still not comprehensive enough for postgraduate cultivation,especially for professional postgraduate degrees.For this reason,Zhejiang University takes the lead in proposing educational reforms for postgraduate cultivation based on the open-source ecosystem.It has implemented a new“trinity”mechanism(i.e.,open-source course,open-source training,and open-source capability evaluation)for graduate training centered on open source,serving as a novel supplement to the traditional methods of postgraduate cultivation.After a year of pilot operation,this new approach,deeply loved by teachers and students,has achieved good results and positive feedback.

Design and research of gymnasium structure in Zhejiang University

This paper deals with the issues involved during the design of a complex gymnasium located at the new campus of Zhejiang University. The complexity comes from the gymnasium’s being of three parts: long-span membrane structure, prestressed concrete structure and extraordinarily long tubular steel structure without seams. The paper first presents considera- tions of the prestress design, followed by analyses of the stress states due to temperature changes and concrete shrinkage. Buckling and postbuckling analyses were performed to determine the load-carrying capacity of the perfect and imperfect tubular steel structure of the inclined arch system, while dynamic relaxation method and general nonlinear finite element analysis were used to carry out shape-finding and stress analyses of the membrane structure respectively. Finally, collated monitoring date was applied to control the construction quality and verify the design parameters. Some useful conclusions are available at the end of the paper.

Research lab on 3D bioprinting of Zhejiang University

OverviewThe Research Lab on 3D Bioprinting of Zhejiang University focuses on developing innovative 3D bioprinting equipment and technology for healthcare and biomedical applications, since founded in 2017. To further enhance the international collaboration, a joint international research lab on 3D bioprinting of Zhejiang University and University of Oxford was set up. The lab is based on the State Key Laboratory of Fluid Power and Mechatronic Systems and the Oxford Centre for Tissue Engineering and Bioprocessing. The aim of the lab is to establish a world class research and development platform on 3D bioprinting. The lab has extensive and close collaborations with University of Oxford, University College London and multidisciplinary partners of Zhejiang University.

Preface to special issue on celebrating the 40th anniversary of Institute of Catalysis, Zhejiang University

In 1978, Professor Songshou Jin, a Chinese prestigious physical chemist, established Institute of Catalysis, Hangzhou University, the forerunner of Institute of Catalysis, Zhejiang University. In 1998, the current Institute of Catalysis was re-established through the merger of Zhejiang University and Hangzhou University et al. During the past forty years, researchers in Institute of Catalysis had always paid much attention to the combination of fundamental researches and industrial applications under the lead of Songshou Jin, Xiaoming Zheng, Weimin Lu, Hui Lou, and Yong Wang. The major research interest includes:(1) basic application research and exploitation of catalysts and catalytic process regarding conversion of biomass, methane, syngas and carbon dioxide;(2) development of catalysts and reaction apparatus for industrial hazardous gas, indoor gas, vehicle emissions and oil smoke from hotels and restaurants;(3) synthesis, characterization of functional materials and their applications in the green synthesis in fields of medicine, pesticide and fine chemical;(4) heterogeneous and homogeneous catalytic reaction kinetics and surface chemistry;(5) catalytic researches regarding military project.

Innovation of Practice Education in Applied Universities： A Study on the ＂Base＂-driven Practice Education System in Zhejiang University City College

Practice education is an important part of application-oriented higher education. Yet it poses many challenges when the design of practice education is questioned concerning whether it actually fulfills the education purpose for high quality future professionals. This paper thus introduces an innovated ＂base＂-driven model of practice education in Zhejiang University City College in China, with a purpose to provide empirical experiences that may be valuable for the decision-making of practice education design in higher education institutions. The paper progresses by examining the philosophy of its innovated model, discussing the framework, and further highlights a strategic consideration when designing practice education activities in higher education institutions.

Disparities in the Levels of Whole-Blood Epstein-Barr Virus between the Cancer and Non-Cancer Populations in Zhejiang,China

Objective This study aimed to investigate the prevalence of Epstein-Barr virus(EBV)infection in patients with and without cancer.Methods A total of 26,648 participants who underwent whole-blood EBV DNA(WBEBV)assays between January 1,2020,and August 31,2023,were included.The chi-square test was used for categorical data analysis,and R software was used to analyze the differences in EBV DNA load levels and the diagnostic capabilities of WBEBV.Results Positive rates were 10.2%and 25.4%for healthy controls(HC)and patients,respectively.The positivity rate for EBV-associated neoplasms(EN)was the highest at 7.53%,followed by leukemia(Le)at 5.49%.The subgroup analysis showed that the positivity rate for abnormal proliferation or hyperplasia(APH)was 31.9%,followed by 30.5%for Le.The WBEBV of patients with transplants(TP),especially living-related transplants(LT),was the highest among all subgroups.WBEBV at diagnosis was used to differentiate between infectious mononucleosis(IM)and chronic active Epstein-Barr virus(CAEBV),with a sensitivity of 67.4%(95%confidence interval[CI]:57.6-75.8)and specificity of 72%(95%CI:63.3-79.3).We conclude that the prevalence of EBV infection is low in the healthy population in this region and that a high EBV load at baseline is more common in LT,IM,and Lymphocyte Leukemia(LL).Conclusion This study used a large-sample survey to characterize the prevalence of whole-blood EBV levels in various diseases,including the stages and subtypes.The EBV detection rate was higher in patients with malignant disease than in those with benign disease.Our study provides clinicians with baseline information regarding EBV-associated diseases.

Spatial distribution of shallow landslides caused by Typhoon Lekima in 2019 in Zhejiang Province, China

In recent years, the coastal region of Southeast China has witnessed a significant increase in the frequency and intensity of extreme rainfall events associated with landfalling typhoons. The hilly and mountainous terrain of this area, combined with rapid rainfall accumulation, has led to a surge in flash floods and severe geological hazards. On August 10, 2019, Typhoon Lekima made landfall in Zhejiang Province, China, and its torrential rainfall triggered extensive landslides, resulting in substantial damage and economic losses. Utilizing high-resolution satellite images, we compiled a landslide inventory of the affected area, which comprises a total of 2,774 rainfallinduced landslides over an area of 2965 km2. The majority of these landslides were small to mediumsized and exhibited elongated, clustered patterns. Some landslides displayed characteristics of high-level initiation, obstructing or partially blocking rivers, leading to the formation of debris dams. We used the inventory to analyze the distribution pattern of the landslides and their relationship with topographical, geological, and hydrological factors. The results showed that landslide abundance was closely related to elevation, slope angle, faults, and road density. The landslides were predominantly located in hilly and low mountainous areas, with elevations ranging from 150 to 300 m, slopes of 20 to 30 degrees, and a NE-SE aspect. Notably, we observed the highest Landslide Number Density(LND) and Landslide Area Percentage(LAP) in the rhyolite region. Landslides were concentrated within approximately 4 km on either side of fault zones, with their size and frequency negatively correlated with distances to faults, roads, and river systems. Furthermore, under the influence of typhoons, regions with denser vegetation cover exhibited higher landslide density, reaching maximum values in shrubland areas. In areas experiencing significantly increased concentrated rainfall, landslide density also showed a corresponding rise. In terms of spatial distribution, the rainfall-triggered landslides primarily occurred in the northeastern part of the study area, particularly in regions characterized by complex topography such as Shanzao Village in Yantan Town, Xixia Township, and Shangzhang Township. The research findings offer crucial data on the rainfallinduced landslides triggered by Typhoon Lekima, shedding light on their spatial distribution patterns. These findings provide valuable references for mitigating risks and planning reconstruction in typhoon-affected area.

China-Africa University Cooperation: Its Practical Relevance, Conceptual Trend and Innovative Mode

Since the Forum on China-Africa Cooperation(FOCAC)was held in 2000,China and Africa have both advocated the expansion of cooperation in the field of education and human resources development,and China-Africa exchanges and cooperation on education have thus ushered in a historical process of fast development.

SPECIALISED READING AT ZHEJIANG UNIVERSITY

This report is based on a questionnaire survey of teachers of specialised reading in Zhejiang University.Fifteen questionnaires out of twenty have been returned from teachers from thirteen departments.They have been involved in the teaching of specialised reading for between one and seven years(onaverage three years).Generally the specialised reading courses run for two hours per week over onesemester(4,5,6.or 7 and more often towards the end of the undergraduate programmes).Howeverthe Philosophy Department and Electrical Engineering spread the course over two semesters(one hourper week).Most teachers teach specialised reading for two hours per week for half the year.

Center of Digital Agriculture and Rural Information,Zhejiang University

Center of Digital Agriculture and Rural Information in Zhejiang University focuses on digital agriculture,Internet of Things(IOT)applications in agriculture and rural information,and has directed over 60 related projects funded by 863 National High-Tech Research and Development Plan,National Support Projects Plan,National Natural Science Foundation Projects and Provincial Key Scientific Projects.It carried on early in China with research in digital agriculture and precision agricultural technologies and equipment,particularly taking the lead in fast acquisition of information of crop life,biological and abiotic stress perception and monitoring,soil nutrient information and physical and chemical index,IOT based plant-soil-environment information acquisition and intelligent fertilizer water irrigation.

A special issue to mark the 90th Anniversary ofCollege of Life Sciences, Zhejiang University

The College of Life Sciences (CLS) remains one of the most prestigious—and the oldest—colleges in Zhejiang University. This special issue, which includes 16 reviews contributed by our alumni and faculties, is dedicated to mark the 90th Anniversary of CLS.

Circulation of Development Factors Promoted by Innovation of Land Management Under Background of Rural Vitalization:A Case Study of Tengtou Village in Zhejiang Province,China

Land is the space carrier for the existence and flow of other development factors.Activating rural land and promoting the circulation of other development factors through land management innovation is necessary to realize rural vitalization.This paper identifies the connotation of factor flow in the rural vitalization context,the action mechanism of land management innovation to boost the flow of development factors,the issues and obstacles restricting factor circulation,and the realization mechanism of the flow of development factors in rural vitalization.Based on the analytic paradigm constructed in the paper,the successful practice of promoting the flow of development factors through innovative land management in a model village is examined.The results show that:1)the unreasonable systems characterized by the land use system in rural areas are the main obstacles causing circulation issues in development factors.It is essential to engage in comprehensive reform to break down these long-lasting obstacles to the smooth flow of development factors.2)The land should play a leading role in the circulation of development factors in the background of rural vitalization;the main purpose of land management innovation is to activate the land factor,thereby promoting the circulation of other factors.3)The activated land factor will act as a‘trigger’to promote capital and technology in rural settings and use capital and technology to attract the inflow of talents and the return of migrant workers,whereby the population factor will act as a‘catalyst’for the cultivation of rural culture,bringing about the integration of various development factors.4)The innovation of land use and management,increased funding,and new technologies have brought multiple talents to Tengtou Village.The high-frequency mutual feedback between the village’s own and the external development factors resulted in its successful integration of industrial development.

Construction of University Librarian Team in the Context of Double First-Class Initiative

Data services,knowledge services,and information services are the core service elements of university libraries in the context of the Double First-Class Initiative.Combined with the current situation of insufficient overall service capacity of libraries,this paper proposed strategies and implementation paths for optimizing the service system from three aspects:the construction of the professional qualification system for librarians,the establishment of post institutions,and the construction of library culture.Long-term path:putting library human resource management into the legal track,taking the lead in local legislation,and promoting the construction of library legislation and professional qualification certification system;optimizing the personnel system,implementing hierarchical management and classified assessment for professional librarians and auxiliary librarians.Short-term path:intensive post allocation,namely,assigning the core strength in the core post,and tackling the temporary major work combining multiple forces in the form of a"working group";building an open knowledge service ecosystem,accelerate the cross-border integration of libraries and other organizations,and striving to build the core competitiveness of libraries.

Comparative Study on Energy Consumption Structure of Ordinary Rural Households and Rural Tourism Households in Zhejiang Province, China

With the rapid development of rural tourism in China, more and more rural households operate a rural tourism business. The purpose of this study is to understand the energy consumption characteristic of ordinary rural households (ORHs) and rural tourism households (RTHs) in the mountainous area and islands area in Zhejiang province. 225 households were surveyed, including 185 ORHs and 40 RTHs, based on a field survey in Quzhou (mountainous area) and Zhoushan (islands area). Results reveal that energy consumption of ORHs is low, but energy comsumption of RTHs is high, about 3 to 5 times higher than that of ORHs. Given the results, the government and RTHs should pay more attention to take measures to reduce energy comsumption. Meanwhile, the factors affecting households’ energy consumption are also analyzed. Energy consumption of ORHs is affected by frequently used area, family income level and permanent population. Then energy consumption of RTHs is mainly related to the total building area, number of air conditioner (AC), number of guestrooms and family income level.

Practice and Features of Neo-Chinese Style in Rural Landscape in Zhejiang Province

Neo-Chinese style is popular nowadays and it is wildly used in rural landscape,with only few theories.Under the background of rural revitalization,this paper discussed practice types and design features of neo-Chinese style in rural landscape.Some typical and famous villages of Ningbo,Quzhou and Lishui cities in Zhejiang Province were chosen as cases in this paper.It is committed to providing some theories,inheriting rural culture and promoting rural revitalization.

A Study on Extreme Temperature and Climate Events in Zhejiang Region of East China

The extreme high temperature anomaly (EHTA) events in a region are one of the most important climatic parameters to make climate assessment of the trend of regional climate change. The diagnosis and analysis of the EHTA event in Zhejiang Province in East China in 2022 show that the event has set the rarest record in this region in the past 71 years from both time and space perspectives. The results of Mann-Kendall trend analysis showed that the mean annual high temperature days in Zhejiang Province had a sudden change. The sudden change occurred around 2004, and the trend was rising after the sudden change.

The early life immune dynamics and cellular drivers at single-cell resolution in lamb forestomachs and abomasum

Background Four-chambered stomach including the forestomachs(rumen,reticulum,and omasum)and abomasum allows ruminants convert plant fiber into high-quality animal products.The early development of this four-chambered stomach is crucial for the health and well-being of young ruminants,especially the immune development.However,the dynamics of immune development are poorly understood.Results We investigated the early gene expression patterns across the four-chambered stomach in Hu sheep,at 5,10,15,and 25 days of age.We found that forestomachs share similar gene expression patterns,all four stomachs underwent widespread activation of both innate and adaptive immune responses from d 5 to 25,whereas the metabolic function were significantly downregulated with age.We constructed a cell landscape of the four-chambered stomach using single-cell sequencing.Integrating transcriptomic and single-cell transcriptomic analyses revealed that the immune-associated module hub genes were highly expressed in T cells,monocytes and macrophages,as well as the defense-associated module hub genes were highly expressed in endothelial cells in the four-stomach tissues.Moreover,the non-immune cells such as epithelial cells play key roles in immune maturation.Cell communication analysis predicted that in addition to immune cells,non-immune cells recruit immune cells through macrophage migration inhibitory factor signaling in the forestomachs.Conclusions Our results demonstrate that the immune and defense responses of four stomachs are quickly developing with age in lamb's early life.We also identified the gene expression patterns and functional cells associated with immune development.Additionally,we identified some key receptors and signaling involved in immune regulation.These results help to understand the early life immune development at single-cell resolution,which has implications to develop nutritional manipulation and health management strategies based on specific targets including key receptors and signaling pathways.

Mechanical Performance of Bio-inspired Bidirectional Corrugated Sandwich Pressure Shell Under External Hydrostatic Pressure

This paper aims to enhance the compression capacity of underwater cylindrical shells by adopting the corrugated sandwich structure of cuttlebone.The cuttlebone suffers uniaxial external compression,while underwater cylindrical shells are in a biaxial compressive stress state.To suit the biaxial compressive stress state,a novel bidirectional corrugated sandwich structure is proposed to improve the bearing capacity of cylindrical shells.The static and buckling analysis for the sandwich shell and the unstiffened cylindrical shell with the same volume-weight ratio are studied by numerical simulation.It is indicated that the proposed sandwich shell can effectively reduce the ratio between circumferential and axial stress from 2 to 1.25 and improve the critical buckling load by about 1.63 times.Numerical simulation shows that optimizing and adjusting the structural parameters could significantly improve the advantage of the sandwich shell.Then,the hydrostatic pressure tests for shell models fabricated by 3D printing are carried out.According to the experimental results,the overall failure position of the sandwich shell is at the center part of the sandwich shell.It has been found the average critical load of the proposed sandwich shell models exceeds two times that of the unstiffened shell models.Hence,the proposed bio-inspired bidirectional corrugated sandwich structure can significantly enhance the pressure resistance capability of cylindrical shells.