AIM:To evaluate the performance of the specific French Vittel "Pre-Hospital(PH) resuscitation" criteria in selecting polytrauma patients during the pre-hospital stage and its potential to increase the positi...AIM:To evaluate the performance of the specific French Vittel "Pre-Hospital(PH) resuscitation" criteria in selecting polytrauma patients during the pre-hospital stage and its potential to increase the positive predictive value(PPV) of pre-hospital trauma triage.METHODS: This was a monocentric prospective cohort study of injured adults transported by emergency medi-cal service to a trauma center. Patients who met any of the field trauma triage criteria were considered "triage positive". Hospital data was statistically linked to prehospital records. The primary outcome of defining a "major trauma patient" was Injury Severity Score(ISS) > 16. RESULTS: There were a total of 200 injured patients evaluated over a 2 years period who met at least 1 triage criterion. The number of false positives was 64 patients(ISS < 16). The PPV was 68%. The sensitivity and the negative predictive value could not be evaluated in this study since it only included patients with positive Vittel criteria. The criterion of "PH resuscitation" was present for 64 patients(32%),but 10 of them had an ISS < 16. This was statistically significant in correlation with the severity of the trauma in univariate analysis(OR = 7.2; P = 0.005; 95%CI: 1.6-31.6). However,despite this correlation the overall PPV was not significantly increased by the use of the criterion "PH resuscitation"(68% vs 67.8%).CONCLUSION: The criterion of "pre-hospital resuscitation" was statistically significant with the severity of the trauma,but did not increase the PPV. The use of "prehospital resuscitation" criterion could be re-considered if these results are confirmed by larger studies.展开更多
<strong>Background:</strong><span style="font-family:Verdana;"> Significant morbidity in children is associated with infectio</span><span style="font-family:Verdana;">...<strong>Background:</strong><span style="font-family:Verdana;"> Significant morbidity in children is associated with infectio</span><span style="font-family:Verdana;">us</span><span style="font-family:Verdana;"> diseases especially soil-transmitted helminth (STH) infections which are prevalent in sub</span><span style="font-family:Verdana;">-</span><span style="font-family:""><span style="font-family:Verdana;">Saharan African countries. The objective of this study is to estimate the prevalence of STH and intestinal protozoa among schoolchildren in Lomé, Togo. </span><b><span style="font-family:Verdana;">Patients and Methods:</span></b><span style="font-family:Verdana;"> In November 2013, in each of the five districts of the Lomé-commune region, thirty pupils per level of the third, fourth, fifth and sixth grades of five primary schools were included. Each child submitted a single stool sample that was analyzed by the Kato-Katz method for STH. In addition, stool</span></span><span style="font-family:""> </span><span style="font-family:""><span style="font-family:Verdana;">samples of school children selected in third and sixth grades were examined by direct visualization using saline and Lugo</span><span><span style="font-family:Verdana;">l’s stain for intestinal protozoa. </span><b><span style="font-family:Verdana;">Results:</span></b><span style="font-family:Verdana;"> A total of 2944 children wer</span></span><span style="font-family:Verdana;">e enrolled at 25 schools. The overall prevalence of STH at schools was 5.0% (range 1.5% to 8.6%), was higher in boys than girls, and increased with age and grade. Hookworm was the most prevalent species (3.4% of children surveyed). Intestinal protozoa were found in 52.2% (765/1465) of children tested and commensal amoebae represented 22.7% of these protozoa identified. </span><i><span style="font-family:Verdana;">Entamoeba histolytica</span></i><span style="font-family:Verdana;">/</span><i><span style="font-family:Verdana;">dispar</span></i><span style="font-family:Verdana;">/</span><i><span style="font-family:Verdana;">moshkovskii</span></i><span style="font-family:Verdana;"> and </span><i><span style="font-family:Verdana;">Giardia intestinalis</span></i><span style="font-family:Verdana;"> were identified i</span><span style="font-family:Verdana;">n 2.3% and 11.5% of children, respectively. Co-infestation was noted in</span><span style="font-family:Verdana;"> 1.35% of children with intestinal helminths and 12.2% of children with protozoa. </span><b><span style="font-family:Verdana;">Conclusion:</span></b><span style="font-family:Verdana;"> Although a high prevalence of intestinal protozoa was found in our study, the majority were non-pathogenic protozoa and the low prev</span><span style="font-family:Verdana;">alence of STH among school-age children in Lomé-commune reg</span><span style="font-family:Verdana;">ion confirms that mass drug administration (MDA) is not needed. Children should receive additional education on best hygiene practices.</span></span>展开更多
This study examined neglected hip fracture-dislocations in developing countries, focusing on five cases in Dakar. The research adopted a prospective method, assessing epidemiological, clinical, radiological, and thera...This study examined neglected hip fracture-dislocations in developing countries, focusing on five cases in Dakar. The research adopted a prospective method, assessing epidemiological, clinical, radiological, and therapeutic aspects, utilizing the Postel Merle d’Aubigné scoring system for functional assessment. Results demonstrated that total joint replacement surgery, predominantly following traffic accidents, significantly improved mobility and reduced limb length disparity, with most patients achieving independent walking post-operation. The study concludes that early diagnosis and total hip arthroplasty are critical for optimal outcomes.展开更多
<b><span style="font-family:Verdana;">Background:</span></b><span style="font-family:""><span style="font-family:Verdana;"> The increasing phenome...<b><span style="font-family:Verdana;">Background:</span></b><span style="font-family:""><span style="font-family:Verdana;"> The increasing phenomenon of bacterial resistance to antibiotics is a real public health problem. The main causes are poor management of hygiene and water quality, but also the use of antibiotics without precaution. The objective of this study was to isolate and determine the antibiotic resistance profile of the different bacteria found in the main hospitals and bacteriology laboratories in Gabon. </span><b><span style="font-family:Verdana;">Methods:</span></b><span style="font-family:Verdana;"> 6034 samples were taken from hospitals in seven main cities of Gabon, and analyzed according to the usual techniques. The pathogenic strains were identified by Matrix-Assisted Laser Desorption Ionization-Time Of Flight Mass Spectrometry. Antimicrobial susceptibility testing was performed by the agar disc diffusion method, according to the Antibiogram Committee of the French Society for Microbiology guidelines. </span><b><span style="font-family:Verdana;">Results: </span></b><span style="font-family:Verdana;">974 pathogenic bacterial strains were found, including 890/974 (91</span><span style="font-family:Verdana;">.4%) Gram-negative bacilli. The systematic antimicrobial suscepti</span><span style="font-family:Verdana;">bility testings identified 160/974 (16.4%) multi-resistant strains. </span><i><span style="font-family:Verdana;">Escherichia coli</span></i><span style="font-family:Verdana;"> was t</span><span style="font-family:Verdana;">he most represented species. 12.5%</span></span><span style="font-family:""> </span><span style="font-family:Verdana;">-</span><span style="font-family:""> </span><span style="font-family:""><span style="font-family:Verdana;">25% of </span><i><span style="font-family:Verdana;">Escherichia coli</span></i><span style="font-family:Verdana;">, </span><i><span style="font-family:Verdana;">Klebsiel</span></i></span><i><span style="font-family:Verdana;">la pneumoniae</span></i><span style="font-family:""><span style="font-family:Verdana;">, </span><i><span style="font-family:Verdana;">Enterobacter cloacae</span></i><span style="font-family:Verdana;">, and </span><i><span style="font-family:Verdana;">Citrobacter sedlakii</span></i><span style="font-family:Verdana;"> strains were resistant to amoxicillin + clavulanic acid, third and fourth generation cephalosporins. Aminoglycoside resistance rates of 8.5%</span></span><span style="font-family:""> </span><span style="font-family:Verdana;">-</span><span style="font-family:""> </span><span style="font-family:""><span style="font-family:Verdana;">19% were also noted. 4.5% to 25% of the bacteria found were resistant to quinolones and cotrimoxazole. Resistance rates to carbapenems ranged from 1% to 10.5%. 16% of </span><i><span style="font-family:Verdana;">Staphylococcus aureus</span></i><span style="font-family:Verdana;"> were methicillin-resistant (MRSA). Rates of extended spectr</span><span style="font-family:Verdana;">um beta-lactamase-producing enterobacteriaceae (ESBL-PE) ran</span><span style="font-family:Verdana;">ged from 2.5% to 25%. </span><b><span style="font-family:Verdana;">Conclusion:</span></b><span style="font-family:Verdana;"> This study showed an increasing evolution of bacteri</span><span style="font-family:Verdana;">al resistance to antibiotics that </span></span><span style="font-family:Verdana;">are</span><span style="font-family:Verdana;"> spreading throughout Gabon. Th</span><span style="font-family:Verdana;">is constitutes a threat to the health of Gabonese population.展开更多
文摘AIM:To evaluate the performance of the specific French Vittel "Pre-Hospital(PH) resuscitation" criteria in selecting polytrauma patients during the pre-hospital stage and its potential to increase the positive predictive value(PPV) of pre-hospital trauma triage.METHODS: This was a monocentric prospective cohort study of injured adults transported by emergency medi-cal service to a trauma center. Patients who met any of the field trauma triage criteria were considered "triage positive". Hospital data was statistically linked to prehospital records. The primary outcome of defining a "major trauma patient" was Injury Severity Score(ISS) > 16. RESULTS: There were a total of 200 injured patients evaluated over a 2 years period who met at least 1 triage criterion. The number of false positives was 64 patients(ISS < 16). The PPV was 68%. The sensitivity and the negative predictive value could not be evaluated in this study since it only included patients with positive Vittel criteria. The criterion of "PH resuscitation" was present for 64 patients(32%),but 10 of them had an ISS < 16. This was statistically significant in correlation with the severity of the trauma in univariate analysis(OR = 7.2; P = 0.005; 95%CI: 1.6-31.6). However,despite this correlation the overall PPV was not significantly increased by the use of the criterion "PH resuscitation"(68% vs 67.8%).CONCLUSION: The criterion of "pre-hospital resuscitation" was statistically significant with the severity of the trauma,but did not increase the PPV. The use of "prehospital resuscitation" criterion could be re-considered if these results are confirmed by larger studies.
文摘<strong>Background:</strong><span style="font-family:Verdana;"> Significant morbidity in children is associated with infectio</span><span style="font-family:Verdana;">us</span><span style="font-family:Verdana;"> diseases especially soil-transmitted helminth (STH) infections which are prevalent in sub</span><span style="font-family:Verdana;">-</span><span style="font-family:""><span style="font-family:Verdana;">Saharan African countries. The objective of this study is to estimate the prevalence of STH and intestinal protozoa among schoolchildren in Lomé, Togo. </span><b><span style="font-family:Verdana;">Patients and Methods:</span></b><span style="font-family:Verdana;"> In November 2013, in each of the five districts of the Lomé-commune region, thirty pupils per level of the third, fourth, fifth and sixth grades of five primary schools were included. Each child submitted a single stool sample that was analyzed by the Kato-Katz method for STH. In addition, stool</span></span><span style="font-family:""> </span><span style="font-family:""><span style="font-family:Verdana;">samples of school children selected in third and sixth grades were examined by direct visualization using saline and Lugo</span><span><span style="font-family:Verdana;">l’s stain for intestinal protozoa. </span><b><span style="font-family:Verdana;">Results:</span></b><span style="font-family:Verdana;"> A total of 2944 children wer</span></span><span style="font-family:Verdana;">e enrolled at 25 schools. The overall prevalence of STH at schools was 5.0% (range 1.5% to 8.6%), was higher in boys than girls, and increased with age and grade. Hookworm was the most prevalent species (3.4% of children surveyed). Intestinal protozoa were found in 52.2% (765/1465) of children tested and commensal amoebae represented 22.7% of these protozoa identified. </span><i><span style="font-family:Verdana;">Entamoeba histolytica</span></i><span style="font-family:Verdana;">/</span><i><span style="font-family:Verdana;">dispar</span></i><span style="font-family:Verdana;">/</span><i><span style="font-family:Verdana;">moshkovskii</span></i><span style="font-family:Verdana;"> and </span><i><span style="font-family:Verdana;">Giardia intestinalis</span></i><span style="font-family:Verdana;"> were identified i</span><span style="font-family:Verdana;">n 2.3% and 11.5% of children, respectively. Co-infestation was noted in</span><span style="font-family:Verdana;"> 1.35% of children with intestinal helminths and 12.2% of children with protozoa. </span><b><span style="font-family:Verdana;">Conclusion:</span></b><span style="font-family:Verdana;"> Although a high prevalence of intestinal protozoa was found in our study, the majority were non-pathogenic protozoa and the low prev</span><span style="font-family:Verdana;">alence of STH among school-age children in Lomé-commune reg</span><span style="font-family:Verdana;">ion confirms that mass drug administration (MDA) is not needed. Children should receive additional education on best hygiene practices.</span></span>
文摘This study examined neglected hip fracture-dislocations in developing countries, focusing on five cases in Dakar. The research adopted a prospective method, assessing epidemiological, clinical, radiological, and therapeutic aspects, utilizing the Postel Merle d’Aubigné scoring system for functional assessment. Results demonstrated that total joint replacement surgery, predominantly following traffic accidents, significantly improved mobility and reduced limb length disparity, with most patients achieving independent walking post-operation. The study concludes that early diagnosis and total hip arthroplasty are critical for optimal outcomes.
文摘<b><span style="font-family:Verdana;">Background:</span></b><span style="font-family:""><span style="font-family:Verdana;"> The increasing phenomenon of bacterial resistance to antibiotics is a real public health problem. The main causes are poor management of hygiene and water quality, but also the use of antibiotics without precaution. The objective of this study was to isolate and determine the antibiotic resistance profile of the different bacteria found in the main hospitals and bacteriology laboratories in Gabon. </span><b><span style="font-family:Verdana;">Methods:</span></b><span style="font-family:Verdana;"> 6034 samples were taken from hospitals in seven main cities of Gabon, and analyzed according to the usual techniques. The pathogenic strains were identified by Matrix-Assisted Laser Desorption Ionization-Time Of Flight Mass Spectrometry. Antimicrobial susceptibility testing was performed by the agar disc diffusion method, according to the Antibiogram Committee of the French Society for Microbiology guidelines. </span><b><span style="font-family:Verdana;">Results: </span></b><span style="font-family:Verdana;">974 pathogenic bacterial strains were found, including 890/974 (91</span><span style="font-family:Verdana;">.4%) Gram-negative bacilli. The systematic antimicrobial suscepti</span><span style="font-family:Verdana;">bility testings identified 160/974 (16.4%) multi-resistant strains. </span><i><span style="font-family:Verdana;">Escherichia coli</span></i><span style="font-family:Verdana;"> was t</span><span style="font-family:Verdana;">he most represented species. 12.5%</span></span><span style="font-family:""> </span><span style="font-family:Verdana;">-</span><span style="font-family:""> </span><span style="font-family:""><span style="font-family:Verdana;">25% of </span><i><span style="font-family:Verdana;">Escherichia coli</span></i><span style="font-family:Verdana;">, </span><i><span style="font-family:Verdana;">Klebsiel</span></i></span><i><span style="font-family:Verdana;">la pneumoniae</span></i><span style="font-family:""><span style="font-family:Verdana;">, </span><i><span style="font-family:Verdana;">Enterobacter cloacae</span></i><span style="font-family:Verdana;">, and </span><i><span style="font-family:Verdana;">Citrobacter sedlakii</span></i><span style="font-family:Verdana;"> strains were resistant to amoxicillin + clavulanic acid, third and fourth generation cephalosporins. Aminoglycoside resistance rates of 8.5%</span></span><span style="font-family:""> </span><span style="font-family:Verdana;">-</span><span style="font-family:""> </span><span style="font-family:""><span style="font-family:Verdana;">19% were also noted. 4.5% to 25% of the bacteria found were resistant to quinolones and cotrimoxazole. Resistance rates to carbapenems ranged from 1% to 10.5%. 16% of </span><i><span style="font-family:Verdana;">Staphylococcus aureus</span></i><span style="font-family:Verdana;"> were methicillin-resistant (MRSA). Rates of extended spectr</span><span style="font-family:Verdana;">um beta-lactamase-producing enterobacteriaceae (ESBL-PE) ran</span><span style="font-family:Verdana;">ged from 2.5% to 25%. </span><b><span style="font-family:Verdana;">Conclusion:</span></b><span style="font-family:Verdana;"> This study showed an increasing evolution of bacteri</span><span style="font-family:Verdana;">al resistance to antibiotics that </span></span><span style="font-family:Verdana;">are</span><span style="font-family:Verdana;"> spreading throughout Gabon. Th</span><span style="font-family:Verdana;">is constitutes a threat to the health of Gabonese population.