This work;It was made to determine the positive and negative usage information, attitudes and behaviors of social networking networks for users. Today, it is well known how the wide social effects of social networking...This work;It was made to determine the positive and negative usage information, attitudes and behaviors of social networking networks for users. Today, it is well known how the wide social effects of social networking sites are widespread and effective. As far as it can be followed from written and visual media, it causes significant damages for attitudes and behaviors for individuals. Looking at the results of the study, it seems impossible to limit the time and necessity of these networks for people, but it is understood that people force their limits and capacity. It was determined that the general acceptance and rejection areas are mixed and the dominant distinctive effects were weakened. Unable to prevent social dissolution and deterioration was realized by these social networks of networks. However, we cannot only talk about negative effects because their positive effects should be mentioned. Data were obtained in this direction. For example, some segments encourage the users of these sites to have more freedom, to develop democracy and human rights awareness. However, the real problem is when and where to stand. This study;Social networking networks use information, attitudes and behaviors;It was carried out for the purpose of evaluating the use of nicknames and networks for the use of networks. The data of the study were obtained by the application of a questionnaire and the data obtained were analyzed with appropriate statistical analysis methods. In the first part of the study, field study/operational concept scanning is performed and theoretical information is included. In the second part, the purpose of the study, the problem status, the importance of the study, limitations, assumptions, problem question, research method, research universe and sample are specified and informed. In the third section, the data obtained using appropriate statistical methods are analyzed. In the last section, some important suggestions and comments are made in the light of the data obtained.展开更多
AIM: To determine whether Nigella sativa prevents hepatic ischemia-reperfusion injury to the liver. METHODS: Thirty rats were divided into three groups as sham (Group 1), control (Group 2), and Nigella sati-va (NS) tr...AIM: To determine whether Nigella sativa prevents hepatic ischemia-reperfusion injury to the liver. METHODS: Thirty rats were divided into three groups as sham (Group 1), control (Group 2), and Nigella sati-va (NS) treatment group (Group 3). All rats underwent hepatic ischemia for 45 min followed by 60 min period of reperfusion. Rats were intraperitoneally infused with only 0.9% saline solution in group 2. Rats in group 3 received NS (0.2 mL/kg) intraperitoneally, before isch-emia and before reperfusion. Blood samples and liver tissues were harvested from the rats, and then the rats were sacrifi ced. Serum aspartate aminotransfera-se (AST), alanine aminotransferase (ALT), and lactate dehydrogenase (LDH) levels were determined. Total antioxidant capacity (TAC), catalase (CAT), total oxida-tive status (TOS), oxidative stress index (OSI) and my-eloperoxidase (MPO) in hepatic tissue were measured. Also liver tissue histopathology was evaluated by light microscopy. RESULTS: The levels of liver enzymes in group 3 weresignifi cantly lower than those in the group 2. TAC in liver tissue was significantly higher in group 3 than in group 2. TOS, OSI and MPO in hepatic tissue were signifi cantly lower in group 3 than the group 2. Histo-logical tissue damage was milder in the NS treatment group than that in the control group. CONCLUSION: Our results suggest that Nigella sa-tiva treatment protects the rat liver against to hepatic ischemia-reperfusion injury.展开更多
The main purpose of this paper is to introduce some approximation properties of a Kantorovich kind q-Bernstein operators related to B′ezier basis functions with shape parameterλ∈[−1,1].Firstly,we compute some basic...The main purpose of this paper is to introduce some approximation properties of a Kantorovich kind q-Bernstein operators related to B′ezier basis functions with shape parameterλ∈[−1,1].Firstly,we compute some basic results such as moments and central moments,and derive the Korovkin type approximation theorem for these operators.Next,we estimate the order of convergence in terms of the usual modulus of continuity,for the functions belong to Lipschitz-type class and Peetre’s K-functional,respectively.Lastly,with the aid of Maple software,we present the comparison of the convergence of these newly defined operators to the certain function with some graphical illustrations and error estimation table.展开更多
In this study, some properties of probiotic yoghurt ice cream supplemented with carob extract and whey powder and viability of L. acidophilus and Bifidobacterium BB-12 on ice-cream were investigated. For this purpose ...In this study, some properties of probiotic yoghurt ice cream supplemented with carob extract and whey powder and viability of L. acidophilus and Bifidobacterium BB-12 on ice-cream were investigated. For this purpose 6 different ice cream was produced with different ratios whey powder and carob extract. The viable probiotic bacteria counts were determined on 1<sup>st</sup>, 7<sup>th</sup>, 30<sup>th</sup>, 60<sup>th</sup> and 90<sup>th</sup> days of storage. Addition of carob extract and whey powder significantly affected all properties of ice-creams. Results showed that the most positive effect on physical, sensory and microbiological properties was observed on sample D which produced with 1% carob extract and 1% whey powder addition.展开更多
<strong>Aim:</strong> This article aimed to investigate the analysis of various methods for eliminating the residual liver cavity after laparoscopic echinococcectomy in patients. <strong>Methods:<...<strong>Aim:</strong> This article aimed to investigate the analysis of various methods for eliminating the residual liver cavity after laparoscopic echinococcectomy in patients. <strong>Methods:</strong> The authors used the following methods of eliminating the residual cavity: omentoplasty (36.8%), abdominalization (30%), drainage of the residual cavity (26.2%), and a combination of omentoplasty with drainage of the residual cavity (7%). <strong>Results:</strong> In the postoperative period, complications occurred in 2 (3.5%) cases in the form of bile leakage from the residual liver cavity. <strong>Conclusions:</strong> It is recommended to use abdominalization and omentoplasty when choosing a method for eliminating the residual liver cavity.展开更多
Objective:To investigate the chest radiography findings,hematological values and the risk factors of the mortality of coronavirus disease 2019(COVID-19).Methods:Patients who were diagnosed with COVID-19 in a secondary...Objective:To investigate the chest radiography findings,hematological values and the risk factors of the mortality of coronavirus disease 2019(COVID-19).Methods:Patients who were diagnosed with COVID-19 in a secondary-level state hospital in Turkey from March to April 2020 were included in the study.COVID-19 diagnosis was confirmed by reverse transcriptase-polymerase chain reaction.Initial routine blood tests and chest radiography findings were examined.The relationship between chest radiography findings and hematological values and risk factors of the mortality of COVID-19 were assessed.Results:In total,94 patients with confirmed COVID-19 diagnosis were included in the study.Among them,33 patients did not have lung involvement(RALE score of 0),and 42 had moderate lung involvement(RALE score of 1 to 4),and 19 had severe lung involvement(RALE score of 5 to 8).Patients with higher RALE scores were significantly elder(P=0.000)and had significantly lower lymphocyte count(P=0.032).Patients in need of intensive care had a lower mean number of platelets compared to patients who did not require intensive care(P=0.007).The receiver operating characteristic analysis revealed that RALE score(P=0.005),age(P=0.002),duration of symptoms(P=0.006),neutrophil-lymphocyte ratio(P=0.007),and lymphocyte percentage(P=0.012)were significantly associated with the risk of mortality.Conclusions:Patients with severe lung involvement have lower lymphocyte values and ratios.Age,RALE score,duration of symptoms,neutrophils/lymphocytes ratio,lymphocytes percentage are risk factors of mortality of COVID-19.展开更多
Irrigated agriculture is the largest consumer of groundwater resources.The interaction between agricultural irrigation and groundwater resources,both in quantity and quality,is often understood later than when the adv...Irrigated agriculture is the largest consumer of groundwater resources.The interaction between agricultural irrigation and groundwater resources,both in quantity and quality,is often understood later than when the adverse effects starts.For more efficient and sustainable utilization of the limited water resources,improved understanding of how respond to irrigation is essential.The Southeastern Anatolia Project(Turkish:GAP)is a major and comprehensive initiative in Turkey.The GAP was a programme to develop water and land resources in the region and planned as a package that comprised 13 individual projects on irrigation and energy production on the Euphrates-Tigris basins.This project includes irrigation networks for an area of approximately 1.8 million hectares.One of the important project sites is Harran Plain having the biggest groundwater resources and the largest irrigation field in the GAP region.Harran Plain has 3,700 km^2 drainage area,1,500 km^2 plain area and 476,000 hectares of irrigation area.Before this project,the irrigations could potentially lead to about 2 m/year decline in groundwater table.After this project application,hydrodynamic system of groundwater has changed.The groundwater level has risen since 1995 in plain.In addition hydrodynamic system has been effected groundwater quality.Results show that a proper irrigation rotation system can implement an efficient water management over the irrigated areas and lead smaller groundwater change and its quality.展开更多
Type 2 diabetes is the most common type of diabetes. Conventionally many drugs are used for the treatment of diabetes such as biguanides, sulfonylureas, meglitinides, etc. But the desired effective treatment is still ...Type 2 diabetes is the most common type of diabetes. Conventionally many drugs are used for the treatment of diabetes such as biguanides, sulfonylureas, meglitinides, etc. But the desired effective treatment is still not to be achieved. So researches are going on for the development of effective alternative therapy against diabetes. Olive leaves are traditionally used in the treatment of the disease. However, studies on its mechanism of action are not yet enough. The aim of this study was to investigate whether olive leaf extract (OLE) improves insulin receptor substrate-1 (IRS-1), tyrosine kinase (TK), GLUT-2, and GLUT-4. Oleuropein levels were analyzed from OLE obtained by using four different solvents, and the highest content of methanol extract was selected for the study. Different concentrations of OLE (2.5 to 320 μg/mL) were incubated with hepatocellular carcinoma (HepG2) cells for 24 hours. After incubation, cell viability was assessed based on luminometric ATP cell viability assay kit. Intracellular reactive oxygen species (ROS) generating level was detected using 2,7dichlorodihydrofluorescein-diacetate (H2DCF-DA) fluorescent probes. Apoptosis was evaluated by acridine orange/ethidium bromide double staining method. Genotoxicity was evaluated by alkaline single cell gel electrophoresis assay (Comet Assay). Protein expression levels of IRS-1, TK, GLUT-2, and GLUT-4 were analyzed by western blotting technique from the obtained cell lysates. Although an optimum doses of OLE (10 μg/mL) maximally increased cell proliferation, decreased ROS generation improved IRS-1, TK, GLUT-2, and GLUT-4 protein expression levels (about fivefold), higher doses (10 to 320 μg/mL) markedly decreased the cell viability, increased DNA damage, apoptosis and ROS generation in a concentration-dependent manner. OLE can be used in the treatment of type 2 diabetes. However, in order to find the most effective and non-toxic concentration, dose optimization is required.展开更多
文摘This work;It was made to determine the positive and negative usage information, attitudes and behaviors of social networking networks for users. Today, it is well known how the wide social effects of social networking sites are widespread and effective. As far as it can be followed from written and visual media, it causes significant damages for attitudes and behaviors for individuals. Looking at the results of the study, it seems impossible to limit the time and necessity of these networks for people, but it is understood that people force their limits and capacity. It was determined that the general acceptance and rejection areas are mixed and the dominant distinctive effects were weakened. Unable to prevent social dissolution and deterioration was realized by these social networks of networks. However, we cannot only talk about negative effects because their positive effects should be mentioned. Data were obtained in this direction. For example, some segments encourage the users of these sites to have more freedom, to develop democracy and human rights awareness. However, the real problem is when and where to stand. This study;Social networking networks use information, attitudes and behaviors;It was carried out for the purpose of evaluating the use of nicknames and networks for the use of networks. The data of the study were obtained by the application of a questionnaire and the data obtained were analyzed with appropriate statistical analysis methods. In the first part of the study, field study/operational concept scanning is performed and theoretical information is included. In the second part, the purpose of the study, the problem status, the importance of the study, limitations, assumptions, problem question, research method, research universe and sample are specified and informed. In the third section, the data obtained using appropriate statistical methods are analyzed. In the last section, some important suggestions and comments are made in the light of the data obtained.
文摘AIM: To determine whether Nigella sativa prevents hepatic ischemia-reperfusion injury to the liver. METHODS: Thirty rats were divided into three groups as sham (Group 1), control (Group 2), and Nigella sati-va (NS) treatment group (Group 3). All rats underwent hepatic ischemia for 45 min followed by 60 min period of reperfusion. Rats were intraperitoneally infused with only 0.9% saline solution in group 2. Rats in group 3 received NS (0.2 mL/kg) intraperitoneally, before isch-emia and before reperfusion. Blood samples and liver tissues were harvested from the rats, and then the rats were sacrifi ced. Serum aspartate aminotransfera-se (AST), alanine aminotransferase (ALT), and lactate dehydrogenase (LDH) levels were determined. Total antioxidant capacity (TAC), catalase (CAT), total oxida-tive status (TOS), oxidative stress index (OSI) and my-eloperoxidase (MPO) in hepatic tissue were measured. Also liver tissue histopathology was evaluated by light microscopy. RESULTS: The levels of liver enzymes in group 3 weresignifi cantly lower than those in the group 2. TAC in liver tissue was significantly higher in group 3 than in group 2. TOS, OSI and MPO in hepatic tissue were signifi cantly lower in group 3 than the group 2. Histo-logical tissue damage was milder in the NS treatment group than that in the control group. CONCLUSION: Our results suggest that Nigella sa-tiva treatment protects the rat liver against to hepatic ischemia-reperfusion injury.
基金This work is supported by the Natural Science Foundation of Fujian Province of China(Grant No.2020J01783)the Project for High-Level Talent Innovation and Entrepreneurship of Quanzhou(Grant No.2018C087R)the Program for New Century Excellent Talents in Fujian Province University.
文摘The main purpose of this paper is to introduce some approximation properties of a Kantorovich kind q-Bernstein operators related to B′ezier basis functions with shape parameterλ∈[−1,1].Firstly,we compute some basic results such as moments and central moments,and derive the Korovkin type approximation theorem for these operators.Next,we estimate the order of convergence in terms of the usual modulus of continuity,for the functions belong to Lipschitz-type class and Peetre’s K-functional,respectively.Lastly,with the aid of Maple software,we present the comparison of the convergence of these newly defined operators to the certain function with some graphical illustrations and error estimation table.
文摘In this study, some properties of probiotic yoghurt ice cream supplemented with carob extract and whey powder and viability of L. acidophilus and Bifidobacterium BB-12 on ice-cream were investigated. For this purpose 6 different ice cream was produced with different ratios whey powder and carob extract. The viable probiotic bacteria counts were determined on 1<sup>st</sup>, 7<sup>th</sup>, 30<sup>th</sup>, 60<sup>th</sup> and 90<sup>th</sup> days of storage. Addition of carob extract and whey powder significantly affected all properties of ice-creams. Results showed that the most positive effect on physical, sensory and microbiological properties was observed on sample D which produced with 1% carob extract and 1% whey powder addition.
文摘<strong>Aim:</strong> This article aimed to investigate the analysis of various methods for eliminating the residual liver cavity after laparoscopic echinococcectomy in patients. <strong>Methods:</strong> The authors used the following methods of eliminating the residual cavity: omentoplasty (36.8%), abdominalization (30%), drainage of the residual cavity (26.2%), and a combination of omentoplasty with drainage of the residual cavity (7%). <strong>Results:</strong> In the postoperative period, complications occurred in 2 (3.5%) cases in the form of bile leakage from the residual liver cavity. <strong>Conclusions:</strong> It is recommended to use abdominalization and omentoplasty when choosing a method for eliminating the residual liver cavity.
文摘Objective:To investigate the chest radiography findings,hematological values and the risk factors of the mortality of coronavirus disease 2019(COVID-19).Methods:Patients who were diagnosed with COVID-19 in a secondary-level state hospital in Turkey from March to April 2020 were included in the study.COVID-19 diagnosis was confirmed by reverse transcriptase-polymerase chain reaction.Initial routine blood tests and chest radiography findings were examined.The relationship between chest radiography findings and hematological values and risk factors of the mortality of COVID-19 were assessed.Results:In total,94 patients with confirmed COVID-19 diagnosis were included in the study.Among them,33 patients did not have lung involvement(RALE score of 0),and 42 had moderate lung involvement(RALE score of 1 to 4),and 19 had severe lung involvement(RALE score of 5 to 8).Patients with higher RALE scores were significantly elder(P=0.000)and had significantly lower lymphocyte count(P=0.032).Patients in need of intensive care had a lower mean number of platelets compared to patients who did not require intensive care(P=0.007).The receiver operating characteristic analysis revealed that RALE score(P=0.005),age(P=0.002),duration of symptoms(P=0.006),neutrophil-lymphocyte ratio(P=0.007),and lymphocyte percentage(P=0.012)were significantly associated with the risk of mortality.Conclusions:Patients with severe lung involvement have lower lymphocyte values and ratios.Age,RALE score,duration of symptoms,neutrophils/lymphocytes ratio,lymphocytes percentage are risk factors of mortality of COVID-19.
文摘Irrigated agriculture is the largest consumer of groundwater resources.The interaction between agricultural irrigation and groundwater resources,both in quantity and quality,is often understood later than when the adverse effects starts.For more efficient and sustainable utilization of the limited water resources,improved understanding of how respond to irrigation is essential.The Southeastern Anatolia Project(Turkish:GAP)is a major and comprehensive initiative in Turkey.The GAP was a programme to develop water and land resources in the region and planned as a package that comprised 13 individual projects on irrigation and energy production on the Euphrates-Tigris basins.This project includes irrigation networks for an area of approximately 1.8 million hectares.One of the important project sites is Harran Plain having the biggest groundwater resources and the largest irrigation field in the GAP region.Harran Plain has 3,700 km^2 drainage area,1,500 km^2 plain area and 476,000 hectares of irrigation area.Before this project,the irrigations could potentially lead to about 2 m/year decline in groundwater table.After this project application,hydrodynamic system of groundwater has changed.The groundwater level has risen since 1995 in plain.In addition hydrodynamic system has been effected groundwater quality.Results show that a proper irrigation rotation system can implement an efficient water management over the irrigated areas and lead smaller groundwater change and its quality.
基金funded by the Bezmialem Vakif University Scientific Research Projects Unit(No:6.2016/57).
文摘Type 2 diabetes is the most common type of diabetes. Conventionally many drugs are used for the treatment of diabetes such as biguanides, sulfonylureas, meglitinides, etc. But the desired effective treatment is still not to be achieved. So researches are going on for the development of effective alternative therapy against diabetes. Olive leaves are traditionally used in the treatment of the disease. However, studies on its mechanism of action are not yet enough. The aim of this study was to investigate whether olive leaf extract (OLE) improves insulin receptor substrate-1 (IRS-1), tyrosine kinase (TK), GLUT-2, and GLUT-4. Oleuropein levels were analyzed from OLE obtained by using four different solvents, and the highest content of methanol extract was selected for the study. Different concentrations of OLE (2.5 to 320 μg/mL) were incubated with hepatocellular carcinoma (HepG2) cells for 24 hours. After incubation, cell viability was assessed based on luminometric ATP cell viability assay kit. Intracellular reactive oxygen species (ROS) generating level was detected using 2,7dichlorodihydrofluorescein-diacetate (H2DCF-DA) fluorescent probes. Apoptosis was evaluated by acridine orange/ethidium bromide double staining method. Genotoxicity was evaluated by alkaline single cell gel electrophoresis assay (Comet Assay). Protein expression levels of IRS-1, TK, GLUT-2, and GLUT-4 were analyzed by western blotting technique from the obtained cell lysates. Although an optimum doses of OLE (10 μg/mL) maximally increased cell proliferation, decreased ROS generation improved IRS-1, TK, GLUT-2, and GLUT-4 protein expression levels (about fivefold), higher doses (10 to 320 μg/mL) markedly decreased the cell viability, increased DNA damage, apoptosis and ROS generation in a concentration-dependent manner. OLE can be used in the treatment of type 2 diabetes. However, in order to find the most effective and non-toxic concentration, dose optimization is required.